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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
YAP1
Full Name:
Yorkie homolog
Alias:
YAP2; YAP65; Yes-associated protein 1, 65kDa
Type:
Transcription, coactivator/corepressor
Mass (Da):
48755
Number AA:
454
UniProt ID:
P46937
International Prot ID:
IPI00009326
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005667
GO:0032991
GO:0043234
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0005515
GO:0005488
PhosphoSite+
KinaseNET
Biological Process:
GO:0006355
GO:0006357
GO:0009893
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S21
Q
G
Q
G
Q
P
P
S
Q
P
P
Q
G
Q
G
Site 2
S31
P
Q
G
Q
G
P
P
S
G
P
G
Q
P
A
P
Site 3
S61
I
V
H
V
R
G
D
S
E
T
D
L
E
A
L
Site 4
T63
H
V
R
G
D
S
E
T
D
L
E
A
L
F
N
Site 5
T77
N
A
V
M
N
P
K
T
A
N
V
P
Q
T
V
Site 6
T83
K
T
A
N
V
P
Q
T
V
P
M
R
L
R
K
Site 7
S94
R
L
R
K
L
P
D
S
F
F
K
P
P
E
P
Site 8
S103
F
K
P
P
E
P
K
S
H
S
R
Q
A
S
T
Site 9
S105
P
P
E
P
K
S
H
S
R
Q
A
S
T
D
A
Site 10
S109
K
S
H
S
R
Q
A
S
T
D
A
G
T
A
G
Site 11
T110
S
H
S
R
Q
A
S
T
D
A
G
T
A
G
A
Site 12
T114
Q
A
S
T
D
A
G
T
A
G
A
L
T
P
Q
Site 13
T119
A
G
T
A
G
A
L
T
P
Q
H
V
R
A
H
Site 14
S127
P
Q
H
V
R
A
H
S
S
P
A
S
L
Q
L
Site 15
S128
Q
H
V
R
A
H
S
S
P
A
S
L
Q
L
G
Site 16
S131
R
A
H
S
S
P
A
S
L
Q
L
G
A
V
S
Site 17
S138
S
L
Q
L
G
A
V
S
P
G
T
L
T
P
T
Site 18
T141
L
G
A
V
S
P
G
T
L
T
P
T
G
V
V
Site 19
T143
A
V
S
P
G
T
L
T
P
T
G
V
V
S
G
Site 20
T145
S
P
G
T
L
T
P
T
G
V
V
S
G
P
A
Site 21
S149
L
T
P
T
G
V
V
S
G
P
A
A
T
P
T
Site 22
T154
V
V
S
G
P
A
A
T
P
T
A
Q
H
L
R
Site 23
T156
S
G
P
A
A
T
P
T
A
Q
H
L
R
Q
S
Site 24
S163
T
A
Q
H
L
R
Q
S
S
F
E
I
P
D
D
Site 25
S164
A
Q
H
L
R
Q
S
S
F
E
I
P
D
D
V
Site 26
T182
A
G
W
E
M
A
K
T
S
S
G
Q
R
Y
F
Site 27
Y188
K
T
S
S
G
Q
R
Y
F
L
N
H
I
D
Q
Site 28
T197
L
N
H
I
D
Q
T
T
T
W
Q
D
P
R
K
Site 29
S208
D
P
R
K
A
M
L
S
Q
M
N
V
T
A
P
Site 30
S217
M
N
V
T
A
P
T
S
P
P
V
Q
Q
N
M
Site 31
S236
S
A
M
N
Q
R
I
S
Q
S
A
P
V
K
Q
Site 32
T378
D
E
M
D
T
G
D
T
I
N
Q
S
T
L
P
Site 33
S382
T
G
D
T
I
N
Q
S
T
L
P
S
Q
Q
N
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation