PhosphoNET

           
Protein Info 
   
Short Name:  GABRA2
Full Name:  Gamma-aminobutyric acid receptor subunit alpha-2
Alias:  GABA(A) receptor subunit alpha-2; GBRA2
Type:  Plasma membrane, Synapse, Postsynaptic membrane, Integral to synaptic vesicle membrane, Cell junction, Integral to membrane protein
Mass (Da):  51326
Number AA:  451
UniProt ID:  P47869
International Prot ID:  IPI00026631
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0030054  GO:0034707  GO:0030285 Uniprot OncoNet
Molecular Function:  GO:0004890  GO:0008503  GO:0005254 PhosphoSite+ KinaseNET
Biological Process:  GO:0006821  GO:0007214  GO:0006836 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1Y53LDRLLDGYDNRLRPG
Site 2Y237IKSSTGEYTVMTAHF
Site 3S278SFWLNRESVPARTVF
Site 4S299TMTTLSISARNSLPK
Site 5Y336IEFATVNYFTKRGWA
Site 6S359DKKKEKASVMIQNNA
Site 7Y367VMIQNNAYAVAVANY
Site 8S379ANYAPNLSKDPVLST
Site 9S385LSKDPVLSTISKSAT
Site 10T386SKDPVLSTISKSATT
Site 11S388DPVLSTISKSATTPE
Site 12T392STISKSATTPEPNKK
Site 13T393TISKSATTPEPNKKP
Site 14T410KPAEAKKTFNSVSKI
Site 15S413EAKKTFNSVSKIDRM
Site 16S415KKTFNSVSKIDRMSR
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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