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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
QARS
Full Name:
Glutaminyl-tRNA synthetase
Alias:
EC 6.1.1.18; Glutamine tRNA ligase; Glutamine-tRNA ligase; Glutamine--tRNA ligase; SYQ
Type:
EC 6.1.1.18; Ligase
Mass (Da):
87799
Number AA:
775
UniProt ID:
P47897
International Prot ID:
IPI00026665
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005829
GO:0005759
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0004819
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0006425
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S6
_
_
M
A
A
L
D
S
L
S
L
F
T
S
L
Site 2
S12
D
S
L
S
L
F
T
S
L
G
L
S
E
Q
K
Site 3
S16
L
F
T
S
L
G
L
S
E
Q
K
A
R
E
T
Site 4
T23
S
E
Q
K
A
R
E
T
L
K
N
S
A
L
S
Site 5
Y57
K
A
T
G
I
L
L
Y
G
L
A
S
R
L
R
Site 6
S61
I
L
L
Y
G
L
A
S
R
L
R
D
T
R
R
Site 7
T66
L
A
S
R
L
R
D
T
R
R
L
S
F
L
V
Site 8
S70
L
R
D
T
R
R
L
S
F
L
V
S
Y
I
A
Site 9
S74
R
R
L
S
F
L
V
S
Y
I
A
S
K
K
I
Site 10
S78
F
L
V
S
Y
I
A
S
K
K
I
H
T
E
P
Site 11
S88
I
H
T
E
P
Q
L
S
A
A
L
E
Y
V
R
Site 12
Y93
Q
L
S
A
A
L
E
Y
V
R
S
H
P
L
D
Site 13
S96
A
A
L
E
Y
V
R
S
H
P
L
D
P
I
D
Site 14
T104
H
P
L
D
P
I
D
T
V
D
F
E
R
E
C
Site 15
Y142
P
Q
L
L
V
E
R
Y
H
F
N
M
G
L
L
Site 16
T199
A
K
A
R
L
E
E
T
D
R
R
T
A
K
D
Site 17
T203
L
E
E
T
D
R
R
T
A
K
D
V
V
E
N
Site 18
T213
D
V
V
E
N
G
E
T
A
D
Q
T
L
S
L
Site 19
T217
N
G
E
T
A
D
Q
T
L
S
L
M
E
Q
L
Site 20
S219
E
T
A
D
Q
T
L
S
L
M
E
Q
L
R
G
Site 21
Y238
F
H
K
P
G
E
N
Y
K
T
P
G
Y
V
V
Site 22
T240
K
P
G
E
N
Y
K
T
P
G
Y
V
V
T
P
Site 23
Y243
E
N
Y
K
T
P
G
Y
V
V
T
P
H
T
M
Site 24
T246
K
T
P
G
Y
V
V
T
P
H
T
M
N
L
L
Site 25
T305
C
F
L
R
F
D
D
T
N
P
E
K
E
E
A
Site 26
Y330
A
W
L
G
Y
T
P
Y
K
V
T
Y
A
S
D
Site 27
Y338
K
V
T
Y
A
S
D
Y
F
D
Q
L
Y
A
W
Site 28
Y356
L
I
R
R
G
L
A
Y
V
C
H
Q
R
G
E
Site 29
T370
E
E
L
K
G
H
N
T
L
P
S
P
W
R
D
Site 30
S373
K
G
H
N
T
L
P
S
P
W
R
D
R
P
M
Site 31
S383
R
D
R
P
M
E
E
S
L
L
L
F
E
A
M
Site 32
S396
A
M
R
K
G
K
F
S
E
G
E
A
T
L
R
Site 33
T401
K
F
S
E
G
E
A
T
L
R
M
K
L
V
M
Site 34
Y422
P
V
A
Y
R
V
K
Y
T
P
H
H
R
T
G
Site 35
T423
V
A
Y
R
V
K
Y
T
P
H
H
R
T
G
D
Site 36
Y467
F
Q
A
R
R
S
S
Y
F
W
L
C
N
A
L
Site 37
Y477
L
C
N
A
L
D
V
Y
C
P
V
Q
W
E
Y
Site 38
Y484
Y
C
P
V
Q
W
E
Y
G
R
L
N
L
H
Y
Site 39
Y491
Y
G
R
L
N
L
H
Y
A
V
V
S
K
R
K
Site 40
T505
K
I
L
Q
L
V
A
T
G
A
V
R
D
W
D
Site 41
T518
W
D
D
P
R
L
F
T
L
T
A
L
R
R
R
Site 42
T520
D
P
R
L
F
T
L
T
A
L
R
R
R
G
F
Site 43
S587
T
N
F
P
A
A
K
S
L
D
I
Q
V
P
N
Site 44
T641
Q
P
V
G
L
R
H
T
G
Y
V
I
E
L
Q
Site 45
S655
Q
H
V
V
K
G
P
S
G
C
V
E
S
L
E
Site 46
S660
G
P
S
G
C
V
E
S
L
E
V
T
C
R
R
Site 47
T664
C
V
E
S
L
E
V
T
C
R
R
A
D
A
G
Site 48
Y692
L
M
C
E
V
R
L
Y
E
R
L
F
Q
H
K
Site 49
T705
H
K
N
P
E
D
P
T
E
V
P
G
G
F
L
Site 50
Y748
F
Q
F
E
R
L
G
Y
F
S
V
D
P
D
S
Site 51
S750
F
E
R
L
G
Y
F
S
V
D
P
D
S
H
Q
Site 52
S755
Y
F
S
V
D
P
D
S
H
Q
G
K
L
V
F
Site 53
T765
G
K
L
V
F
N
R
T
V
T
L
K
E
D
P
Site 54
T767
L
V
F
N
R
T
V
T
L
K
E
D
P
G
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation