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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ZFP36L2
Full Name:
Zinc finger protein 36, C3H1 type-like 2
Alias:
BRF2; EGF-response factor 2; ERF2; ERF-2; RNF162C; TIS11D; TISD; Zinc finger protein 36, C3H type-like 1
Type:
Cytoplasm, Nucleus protein
Mass (Da):
51063
Number AA:
494
UniProt ID:
P47974
International Prot ID:
IPI00026947
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003723
GO:0003700
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0008283
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T18
D
V
D
F
L
C
K
T
E
K
S
L
A
N
L
Site 2
S21
F
L
C
K
T
E
K
S
L
A
N
L
N
L
N
Site 3
S57
P
G
F
L
R
R
H
S
A
S
N
L
H
A
L
Site 4
S59
F
L
R
R
H
S
A
S
N
L
H
A
L
A
H
Site 5
S70
A
L
A
H
P
A
P
S
P
G
S
C
S
P
K
Site 6
S73
H
P
A
P
S
P
G
S
C
S
P
K
F
P
G
Site 7
S75
A
P
S
P
G
S
C
S
P
K
F
P
G
A
A
Site 8
S86
P
G
A
A
N
G
S
S
C
G
S
A
A
A
G
Site 9
S89
A
N
G
S
S
C
G
S
A
A
A
G
G
P
T
Site 10
S97
A
A
A
G
G
P
T
S
Y
G
T
L
K
E
P
Site 11
T100
G
G
P
T
S
Y
G
T
L
K
E
P
S
G
G
Site 12
S105
Y
G
T
L
K
E
P
S
G
G
G
G
T
A
L
Site 13
S123
E
N
K
F
R
D
R
S
F
S
E
N
G
D
R
Site 14
S125
K
F
R
D
R
S
F
S
E
N
G
D
R
S
Q
Site 15
S131
F
S
E
N
G
D
R
S
Q
H
L
L
H
L
Q
Site 16
S147
Q
Q
K
G
G
G
G
S
Q
I
N
S
T
R
Y
Site 17
S151
G
G
G
S
Q
I
N
S
T
R
Y
K
T
E
L
Site 18
T156
I
N
S
T
R
Y
K
T
E
L
C
R
P
F
E
Site 19
S165
L
C
R
P
F
E
E
S
G
T
C
K
Y
G
E
Site 20
T167
R
P
F
E
E
S
G
T
C
K
Y
G
E
K
C
Site 21
Y170
E
E
S
G
T
C
K
Y
G
E
K
C
Q
F
A
Site 22
S185
H
G
F
H
E
L
R
S
L
T
R
H
P
K
Y
Site 23
T187
F
H
E
L
R
S
L
T
R
H
P
K
Y
K
T
Site 24
Y192
S
L
T
R
H
P
K
Y
K
T
E
L
C
R
T
Site 25
T194
T
R
H
P
K
Y
K
T
E
L
C
R
T
F
H
Site 26
Y208
H
T
I
G
F
C
P
Y
G
P
R
C
H
F
I
Site 27
S226
D
E
R
R
P
A
P
S
G
G
A
S
G
D
L
Site 28
S230
P
A
P
S
G
G
A
S
G
D
L
R
A
F
G
Site 29
T238
G
D
L
R
A
F
G
T
R
D
A
L
H
L
G
Site 30
S257
P
R
P
K
L
H
H
S
L
S
F
S
G
F
P
Site 31
S259
P
K
L
H
H
S
L
S
F
S
G
F
P
S
G
Site 32
S261
L
H
H
S
L
S
F
S
G
F
P
S
G
H
H
Site 33
S265
L
S
F
S
G
F
P
S
G
H
H
Q
P
P
G
Site 34
S276
Q
P
P
G
G
L
E
S
P
L
L
L
D
S
P
Site 35
S282
E
S
P
L
L
L
D
S
P
T
S
R
T
P
P
Site 36
T284
P
L
L
L
D
S
P
T
S
R
T
P
P
P
P
Site 37
S285
L
L
L
D
S
P
T
S
R
T
P
P
P
P
S
Site 38
T287
L
D
S
P
T
S
R
T
P
P
P
P
S
C
S
Site 39
S292
S
R
T
P
P
P
P
S
C
S
S
A
S
S
C
Site 40
S294
T
P
P
P
P
S
C
S
S
A
S
S
C
S
S
Site 41
S295
P
P
P
P
S
C
S
S
A
S
S
C
S
S
S
Site 42
S297
P
P
S
C
S
S
A
S
S
C
S
S
S
A
S
Site 43
S298
P
S
C
S
S
A
S
S
C
S
S
S
A
S
S
Site 44
S300
C
S
S
A
S
S
C
S
S
S
A
S
S
C
S
Site 45
S301
S
S
A
S
S
C
S
S
S
A
S
S
C
S
S
Site 46
S302
S
A
S
S
C
S
S
S
A
S
S
C
S
S
A
Site 47
S304
S
S
C
S
S
S
A
S
S
C
S
S
A
S
A
Site 48
S305
S
C
S
S
S
A
S
S
C
S
S
A
S
A
A
Site 49
S307
S
S
S
A
S
S
C
S
S
A
S
A
A
S
T
Site 50
S308
S
S
A
S
S
C
S
S
A
S
A
A
S
T
P
Site 51
S310
A
S
S
C
S
S
A
S
A
A
S
T
P
S
G
Site 52
T314
S
S
A
S
A
A
S
T
P
S
G
A
P
T
C
Site 53
Y391
A
A
V
A
A
A
A
Y
Y
R
S
Q
Q
Q
Q
Site 54
S414
A
Q
P
P
A
P
P
S
A
T
L
P
A
G
A
Site 55
S430
A
P
P
S
P
P
F
S
F
Q
L
P
R
R
L
Site 56
S438
F
Q
L
P
R
R
L
S
D
S
P
V
F
D
A
Site 57
S440
L
P
R
R
L
S
D
S
P
V
F
D
A
P
P
Site 58
S448
P
V
F
D
A
P
P
S
P
P
D
S
L
S
D
Site 59
S452
A
P
P
S
P
P
D
S
L
S
D
R
D
S
Y
Site 60
S454
P
S
P
P
D
S
L
S
D
R
D
S
Y
L
S
Site 61
S458
D
S
L
S
D
R
D
S
Y
L
S
G
S
L
S
Site 62
Y459
S
L
S
D
R
D
S
Y
L
S
G
S
L
S
S
Site 63
S461
S
D
R
D
S
Y
L
S
G
S
L
S
S
G
S
Site 64
S463
R
D
S
Y
L
S
G
S
L
S
S
G
S
L
S
Site 65
S465
S
Y
L
S
G
S
L
S
S
G
S
L
S
G
S
Site 66
S466
Y
L
S
G
S
L
S
S
G
S
L
S
G
S
E
Site 67
S468
S
G
S
L
S
S
G
S
L
S
G
S
E
S
P
Site 68
S470
S
L
S
S
G
S
L
S
G
S
E
S
P
S
L
Site 69
S472
S
S
G
S
L
S
G
S
E
S
P
S
L
D
P
Site 70
S474
G
S
L
S
G
S
E
S
P
S
L
D
P
G
R
Site 71
S476
L
S
G
S
E
S
P
S
L
D
P
G
R
R
L
Site 72
S487
G
R
R
L
P
I
F
S
R
L
S
I
S
D
D
Site 73
S490
L
P
I
F
S
R
L
S
I
S
D
D
_
_
_
Site 74
S492
I
F
S
R
L
S
I
S
D
D
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation