PhosphoNET

           
Protein Info 
   
Short Name:  LIMS1
Full Name:  LIM and senescent cell antigen-like-containing domain protein 1
Alias:  LIM and senescent cell antigen-like domains 1; Particularly interesting new Cys-His protein; PINCH; PINCH1; PINCH-1
Type:  Adaptor/scaffold
Mass (Da):  37251
Number AA:  324
UniProt ID:  P48059
International Prot ID:  IPI00007634
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005925     Uniprot OncoNet
Molecular Function:  GO:0005515  GO:0008270   PhosphoSite+ KinaseNET
Biological Process:  GO:0007569     Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S26PAEKIVNSNGELYHE
Site 2Y31VNSNGELYHEQCFVC
Site 3Y51QFPEGLFYEFEGRKY
Site 4Y58YEFEGRKYCEHDFQM
Site 5Y133KARGLGKYICQKCHA
Site 6Y180RELKGELYCLPCHDK
Site 7Y232PFLGHRHYERKGLAY
Site 8Y239YERKGLAYCETHYNQ
Site 9Y244LAYCETHYNQLFGDV
Site 10T286STCNTKLTLKNKFVE
Site 11Y304KPVCKKCYEKFPLEL
Site 12T321RLKKLAETLGRK___
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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