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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SLC6A11
Full Name:
Sodium- and chloride-dependent GABA transporter 3
Alias:
GABT3; GAT3; GAT-3; S6A11
Type:
Membrane, Integral plasma membrane protein
Mass (Da):
70606
Number AA:
632
UniProt ID:
P48066
International Prot ID:
IPI00007648
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005887
Uniprot
OncoNet
Molecular Function:
GO:0005332
GO:0005328
PhosphoSite+
KinaseNET
Biological Process:
GO:0006836
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S21
A
A
E
E
A
R
E
S
E
A
P
G
G
G
C
Site 2
S30
A
P
G
G
G
C
S
S
G
G
A
A
P
A
R
Site 3
Y78
G
N
V
W
R
F
P
Y
L
C
Y
K
N
G
G
Site 4
Y81
W
R
F
P
Y
L
C
Y
K
N
G
G
G
A
F
Site 5
S189
E
F
Q
K
L
N
V
S
N
Y
S
H
V
S
L
Site 6
Y240
L
A
A
W
T
I
C
Y
F
C
I
W
K
G
T
Site 7
Y285
A
S
E
G
I
K
F
Y
L
Y
P
D
L
S
R
Site 8
Y287
E
G
I
K
F
Y
L
Y
P
D
L
S
R
L
S
Site 9
S291
F
Y
L
Y
P
D
L
S
R
L
S
D
P
Q
V
Site 10
S294
Y
P
D
L
S
R
L
S
D
P
Q
V
W
V
D
Site 11
Y326
A
L
G
S
Y
N
N
Y
N
N
N
C
Y
R
D
Site 12
Y434
P
K
V
F
R
R
G
Y
R
R
E
L
L
I
L
Site 13
Y497
V
Y
G
S
N
R
F
Y
D
N
I
E
D
M
I
Site 14
Y506
N
I
E
D
M
I
G
Y
R
P
P
S
L
I
K
Site 15
Y540
I
K
Y
K
P
L
K
Y
N
N
I
Y
T
Y
P
Site 16
Y544
P
L
K
Y
N
N
I
Y
T
Y
P
A
W
G
Y
Site 17
T588
P
E
K
L
Q
K
L
T
T
P
S
T
D
L
K
Site 18
T589
E
K
L
Q
K
L
T
T
P
S
T
D
L
K
M
Site 19
S591
L
Q
K
L
T
T
P
S
T
D
L
K
M
R
G
Site 20
T592
Q
K
L
T
T
P
S
T
D
L
K
M
R
G
K
Site 21
S603
M
R
G
K
L
G
V
S
P
R
M
V
T
V
N
Site 22
T608
G
V
S
P
R
M
V
T
V
N
D
C
D
A
K
Site 23
S618
D
C
D
A
K
L
K
S
D
G
T
I
A
A
I
Site 24
T621
A
K
L
K
S
D
G
T
I
A
A
I
T
E
K
Site 25
T630
A
A
I
T
E
K
E
T
H
F
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation