KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
GABRA4
Full Name:
Gamma-aminobutyric acid receptor subunit alpha-4
Alias:
GABA(A) receptor subunit alpha-4; Gamma-aminobutyric acid (GABA) A receptor, alpha 4; GBRA4
Type:
Plasma membrane, Integral plasma membrane, Postsynaptic membrane, Synapse, Cell junction protein
Mass (Da):
61623
Number AA:
554
UniProt ID:
P48169
International Prot ID:
IPI00008225
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0030054
GO:0034707
GO:0005887
Uniprot
OncoNet
Molecular Function:
GO:0004890
GO:0008503
GO:0005254
PhosphoSite+
KinaseNET
Biological Process:
GO:0006821
GO:0007214
Phosida
TranscriptoNet
STRING
Kinexus Products
Gamma-aminobutyric acid receptor subunit alpha-4 pan-specific antibody AB-NN251-1#http://www.kinexusproducts.ca/ProductInfo_Antibody.aspx?Product_Number=AB-NN251-1
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S33
L
A
V
C
L
N
E
S
P
G
Q
N
Q
K
E
Site 2
S140
F
F
R
N
G
K
K
S
V
S
H
N
M
T
A
Site 3
S142
R
N
G
K
K
S
V
S
H
N
M
T
A
P
N
Site 4
T146
K
S
V
S
H
N
M
T
A
P
N
K
L
F
R
Site 5
S284
S
F
W
I
N
K
E
S
V
P
A
R
T
V
F
Site 6
S305
T
M
T
T
L
S
I
S
A
R
H
S
L
P
K
Site 7
S309
L
S
I
S
A
R
H
S
L
P
K
V
S
Y
A
Site 8
T355
M
E
K
A
K
R
K
T
S
K
P
P
Q
E
V
Site 9
S356
E
K
A
K
R
K
T
S
K
P
P
Q
E
V
P
Site 10
T390
N
L
N
M
R
K
R
T
N
A
L
V
H
S
E
Site 11
S396
R
T
N
A
L
V
H
S
E
S
D
V
G
N
R
Site 12
S398
N
A
L
V
H
S
E
S
D
V
G
N
R
T
E
Site 13
T404
E
S
D
V
G
N
R
T
E
V
G
N
H
S
S
Site 14
S410
R
T
E
V
G
N
H
S
S
K
S
S
T
V
V
Site 15
S411
T
E
V
G
N
H
S
S
K
S
S
T
V
V
Q
Site 16
S413
V
G
N
H
S
S
K
S
S
T
V
V
Q
E
S
Site 17
S414
G
N
H
S
S
K
S
S
T
V
V
Q
E
S
S
Site 18
T415
N
H
S
S
K
S
S
T
V
V
Q
E
S
S
K
Site 19
S420
S
S
T
V
V
Q
E
S
S
K
G
T
P
R
S
Site 20
T424
V
Q
E
S
S
K
G
T
P
R
S
Y
L
A
S
Site 21
S427
S
S
K
G
T
P
R
S
Y
L
A
S
S
P
N
Site 22
Y428
S
K
G
T
P
R
S
Y
L
A
S
S
P
N
P
Site 23
S431
T
P
R
S
Y
L
A
S
S
P
N
P
F
S
R
Site 24
S432
P
R
S
Y
L
A
S
S
P
N
P
F
S
R
A
Site 25
S437
A
S
S
P
N
P
F
S
R
A
N
A
A
E
T
Site 26
S453
S
A
A
R
A
L
P
S
A
S
P
T
S
I
R
Site 27
S455
A
R
A
L
P
S
A
S
P
T
S
I
R
T
G
Site 28
T457
A
L
P
S
A
S
P
T
S
I
R
T
G
Y
M
Site 29
S458
L
P
S
A
S
P
T
S
I
R
T
G
Y
M
P
Site 30
Y463
P
T
S
I
R
T
G
Y
M
P
R
K
A
S
V
Site 31
S469
G
Y
M
P
R
K
A
S
V
G
S
A
S
T
R
Site 32
S474
K
A
S
V
G
S
A
S
T
R
H
V
F
G
S
Site 33
S481
S
T
R
H
V
F
G
S
R
L
Q
R
I
K
T
Site 34
T488
S
R
L
Q
R
I
K
T
T
V
N
T
I
G
A
Site 35
S500
I
G
A
T
G
K
L
S
A
T
P
P
P
S
A
Site 36
T502
A
T
G
K
L
S
A
T
P
P
P
S
A
P
P
Site 37
S506
L
S
A
T
P
P
P
S
A
P
P
P
S
G
S
Site 38
S511
P
P
S
A
P
P
P
S
G
S
G
T
S
K
I
Site 39
S513
S
A
P
P
P
S
G
S
G
T
S
K
I
D
K
Site 40
T515
P
P
P
S
G
S
G
T
S
K
I
D
K
Y
A
Site 41
Y521
G
T
S
K
I
D
K
Y
A
R
I
L
F
P
V
Site 42
Y541
N
M
V
Y
W
V
V
Y
L
S
K
D
T
M
E
Site 43
T546
V
V
Y
L
S
K
D
T
M
E
K
S
E
S
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation