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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SOX9
Full Name:
Transcription factor SOX-9
Alias:
CMD1; CMPD1; SRA1; SRY (sex determining region Y)-box 9
Type:
Transcription protein
Mass (Da):
56137
Number AA:
509
UniProt ID:
P48436
International Prot ID:
IPI00009713
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003704
PhosphoSite+
KinaseNET
Biological Process:
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T11
L
D
P
F
M
K
M
T
D
E
Q
E
K
G
L
Site 2
S19
D
E
Q
E
K
G
L
S
G
A
P
S
P
T
M
Site 3
S23
K
G
L
S
G
A
P
S
P
T
M
S
E
D
S
Site 4
S27
G
A
P
S
P
T
M
S
E
D
S
A
G
S
P
Site 5
S30
S
P
T
M
S
E
D
S
A
G
S
P
C
P
S
Site 6
S33
M
S
E
D
S
A
G
S
P
C
P
S
G
S
G
Site 7
S37
S
A
G
S
P
C
P
S
G
S
G
S
D
T
E
Site 8
S39
G
S
P
C
P
S
G
S
G
S
D
T
E
N
T
Site 9
S41
P
C
P
S
G
S
G
S
D
T
E
N
T
R
P
Site 10
T43
P
S
G
S
G
S
D
T
E
N
T
R
P
Q
E
Site 11
T46
S
G
S
D
T
E
N
T
R
P
Q
E
N
T
F
Site 12
T52
N
T
R
P
Q
E
N
T
F
P
K
G
E
P
D
Site 13
S64
E
P
D
L
K
K
E
S
E
E
D
K
F
P
V
Site 14
S99
P
V
R
V
N
G
S
S
K
N
K
P
H
V
K
Site 15
Y127
R
R
K
L
A
D
Q
Y
P
H
L
H
N
A
E
Site 16
T138
H
N
A
E
L
S
K
T
L
G
K
L
W
R
L
Site 17
S149
L
W
R
L
L
N
E
S
E
K
R
P
F
V
E
Site 18
Y172
H
K
K
D
H
P
D
Y
K
Y
Q
P
R
R
R
Site 19
Y174
K
D
H
P
D
Y
K
Y
Q
P
R
R
R
K
S
Site 20
S181
Y
Q
P
R
R
R
K
S
V
K
N
G
Q
A
E
Site 21
S199
A
T
E
Q
T
H
I
S
P
N
A
I
F
K
A
Site 22
S211
F
K
A
L
Q
A
D
S
P
H
S
S
S
G
M
Site 23
S214
L
Q
A
D
S
P
H
S
S
S
G
M
S
E
V
Site 24
S215
Q
A
D
S
P
H
S
S
S
G
M
S
E
V
H
Site 25
S216
A
D
S
P
H
S
S
S
G
M
S
E
V
H
S
Site 26
S219
P
H
S
S
S
G
M
S
E
V
H
S
P
G
E
Site 27
S223
S
G
M
S
E
V
H
S
P
G
E
H
S
G
Q
Site 28
S231
P
G
E
H
S
G
Q
S
Q
G
P
P
T
P
P
Site 29
T236
G
Q
S
Q
G
P
P
T
P
P
T
T
P
K
T
Site 30
T239
Q
G
P
P
T
P
P
T
T
P
K
T
D
V
Q
Site 31
T240
G
P
P
T
P
P
T
T
P
K
T
D
V
Q
P
Site 32
T243
T
P
P
T
T
P
K
T
D
V
Q
P
G
K
A
Site 33
T288
D
V
I
S
N
I
E
T
F
D
V
N
E
F
D
Site 34
Y297
D
V
N
E
F
D
Q
Y
L
P
P
N
G
H
P
Site 35
T309
G
H
P
G
V
P
A
T
H
G
Q
V
T
Y
T
Site 36
T314
P
A
T
H
G
Q
V
T
Y
T
G
S
Y
G
I
Site 37
Y315
A
T
H
G
Q
V
T
Y
T
G
S
Y
G
I
S
Site 38
T316
T
H
G
Q
V
T
Y
T
G
S
Y
G
I
S
S
Site 39
S318
G
Q
V
T
Y
T
G
S
Y
G
I
S
S
T
A
Site 40
S322
Y
T
G
S
Y
G
I
S
S
T
A
A
T
P
A
Site 41
S323
T
G
S
Y
G
I
S
S
T
A
A
T
P
A
S
Site 42
T381
P
Q
Q
P
Q
A
H
T
L
T
T
L
S
S
E
Site 43
T383
Q
P
Q
A
H
T
L
T
T
L
S
S
E
P
G
Site 44
T384
P
Q
A
H
T
L
T
T
L
S
S
E
P
G
Q
Site 45
S386
A
H
T
L
T
T
L
S
S
E
P
G
Q
S
Q
Site 46
S387
H
T
L
T
T
L
S
S
E
P
G
Q
S
Q
R
Site 47
S392
L
S
S
E
P
G
Q
S
Q
R
T
H
I
K
T
Site 48
T399
S
Q
R
T
H
I
K
T
E
Q
L
S
P
S
H
Site 49
S403
H
I
K
T
E
Q
L
S
P
S
H
Y
S
E
Q
Site 50
S405
K
T
E
Q
L
S
P
S
H
Y
S
E
Q
Q
Q
Site 51
Y407
E
Q
L
S
P
S
H
Y
S
E
Q
Q
Q
H
S
Site 52
S414
Y
S
E
Q
Q
Q
H
S
P
Q
Q
I
A
Y
S
Site 53
S421
S
P
Q
Q
I
A
Y
S
P
F
N
L
P
H
Y
Site 54
Y428
S
P
F
N
L
P
H
Y
S
P
S
Y
P
P
I
Site 55
S429
P
F
N
L
P
H
Y
S
P
S
Y
P
P
I
T
Site 56
S431
N
L
P
H
Y
S
P
S
Y
P
P
I
T
R
S
Site 57
Y432
L
P
H
Y
S
P
S
Y
P
P
I
T
R
S
Q
Site 58
T436
S
P
S
Y
P
P
I
T
R
S
Q
Y
D
Y
T
Site 59
S438
S
Y
P
P
I
T
R
S
Q
Y
D
Y
T
D
H
Site 60
Y440
P
P
I
T
R
S
Q
Y
D
Y
T
D
H
Q
N
Site 61
Y442
I
T
R
S
Q
Y
D
Y
T
D
H
Q
N
S
S
Site 62
T443
T
R
S
Q
Y
D
Y
T
D
H
Q
N
S
S
S
Site 63
S448
D
Y
T
D
H
Q
N
S
S
S
Y
Y
S
H
A
Site 64
S449
Y
T
D
H
Q
N
S
S
S
Y
Y
S
H
A
A
Site 65
S450
T
D
H
Q
N
S
S
S
Y
Y
S
H
A
A
G
Site 66
Y452
H
Q
N
S
S
S
Y
Y
S
H
A
A
G
Q
G
Site 67
S453
Q
N
S
S
S
Y
Y
S
H
A
A
G
Q
G
T
Site 68
Y463
A
G
Q
G
T
G
L
Y
S
T
F
T
Y
M
N
Site 69
T465
Q
G
T
G
L
Y
S
T
F
T
Y
M
N
P
A
Site 70
T467
T
G
L
Y
S
T
F
T
Y
M
N
P
A
Q
R
Site 71
Y468
G
L
Y
S
T
F
T
Y
M
N
P
A
Q
R
P
Site 72
Y477
N
P
A
Q
R
P
M
Y
T
P
I
A
D
T
S
Site 73
T478
P
A
Q
R
P
M
Y
T
P
I
A
D
T
S
G
Site 74
S484
Y
T
P
I
A
D
T
S
G
V
P
S
I
P
Q
Site 75
S488
A
D
T
S
G
V
P
S
I
P
Q
T
H
S
P
Site 76
T492
G
V
P
S
I
P
Q
T
H
S
P
Q
H
W
E
Site 77
S494
P
S
I
P
Q
T
H
S
P
Q
H
W
E
Q
P
Site 78
Y503
Q
H
W
E
Q
P
V
Y
T
Q
L
T
R
P
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation