PhosphoNET

           
Protein Info 
   
Short Name:  Kv3.1
Full Name:  Potassium voltage-gated channel subfamily C member 1
Alias:  KCNC1; Kv4; NGK2; Potassium voltage-gated channel, Shaw-related subfamily, member 1; Voltage-gated potassium channel subunit Kv3.1; Voltage-gated potassium channel subunit Kv4
Type:  Channel, potassium
Mass (Da):  57942
Number AA:  511
UniProt ID:  P48547
International Prot ID:  IPI00010174
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0008076     Uniprot OncoNet
Molecular Function:  GO:0030955  GO:0005515  GO:0005249 PhosphoSite+ KinaseNET
Biological Process:  GO:0006813  GO:0055085   Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1T21VGGTRHQTYRSTLRT
Site 2Y22GGTRHQTYRSTLRTL
Site 3S24TRHQTYRSTLRTLPG
Site 4T25RHQTYRSTLRTLPGT
Site 5T28TYRSTLRTLPGTRLA
Site 6Y48DAHSHFDYDPRADEF
Site 7Y70VFAHILNYYRTGKLH
Site 8Y71FAHILNYYRTGKLHC
Site 9S121DAEEALDSFGGAPLD
Site 10S142DADGPGDSGDGEDEL
Site 11T152GEDELEMTKRLALSD
Site 12S158MTKRLALSDSPDGRP
Site 13S160KRLALSDSPDGRPGG
Site 14Y184WALFEDPYSSRYARY
Site 15S185ALFEDPYSSRYARYV
Site 16Y188EDPYSSRYARYVAFA
Site 17T231IENVRNGTQVRYYRE
Site 18Y235RNGTQVRYYREAETE
Site 19Y236NGTQVRYYREAETEA
Site 20T337GLRVLGHTLRASTNE
Site 21T342GHTLRASTNEFLLLI
Site 22S377GAQPNDPSASEHTHF
Site 23Y407TLGYGDMYPQTWSGM
Site 24S468PRPPQLGSPNYCKSV
Site 25Y471PQLGSPNYCKSVVNS
Site 26S474GSPNYCKSVVNSPHH
Site 27S478YCKSVVNSPHHSTQS
Site 28S482VVNSPHHSTQSDTCP
Site 29S485SPHHSTQSDTCPLAQ
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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