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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PTDSS1
Full Name:
Phosphatidylserine synthase 1
Alias:
KIAA0024; Phosphatidylserine synthase I; PSS1; PSS-1; PSSA; PtdSer synthase-1; PTSS1; Serine-exchange enzyme I
Type:
Transferase; Mitochondrial; Lipid Metabolism - glycerophospholipid; EC 2.7.8.-
Mass (Da):
55528
Number AA:
473
UniProt ID:
P48651
International Prot ID:
IPI00010746
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
GO:0016021
GO:0031224
Uniprot
OncoNet
Molecular Function:
GO:0016740
GO:0016740
PhosphoSite+
KinaseNET
Biological Process:
GO:0006659
GO:0006643
GO:0006644
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S3
_
_
_
_
_
M
A
S
C
V
G
S
R
T
L
Site 2
S7
_
M
A
S
C
V
G
S
R
T
L
S
K
D
D
Site 3
T9
A
S
C
V
G
S
R
T
L
S
K
D
D
V
N
Site 4
S11
C
V
G
S
R
T
L
S
K
D
D
V
N
Y
K
Site 5
Y17
L
S
K
D
D
V
N
Y
K
M
H
F
R
M
I
Site 6
T33
E
Q
Q
V
E
D
I
T
I
D
F
F
Y
R
P
Site 7
S63
F
A
F
T
R
D
D
S
V
P
E
D
N
I
W
Site 8
T94
A
F
P
N
G
P
F
T
R
P
H
P
A
L
W
Site 9
T141
D
P
N
L
R
Y
A
T
R
E
A
D
V
M
E
Site 10
Y245
R
F
L
E
M
R
T
Y
H
W
A
S
F
K
D
Site 11
T255
A
S
F
K
D
I
H
T
T
T
G
K
I
K
R
Site 12
T268
K
R
A
V
L
Q
F
T
P
A
S
W
T
Y
V
Site 13
S282
V
R
W
F
D
P
K
S
S
F
Q
R
V
A
G
Site 14
S283
R
W
F
D
P
K
S
S
F
Q
R
V
A
G
V
Site 15
Y338
T
A
P
T
V
R
Q
Y
Y
A
Y
L
T
D
T
Site 16
Y339
A
P
T
V
R
Q
Y
Y
A
Y
L
T
D
T
Q
Site 17
Y341
T
V
R
Q
Y
Y
A
Y
L
T
D
T
Q
C
K
Site 18
T345
Y
Y
A
Y
L
T
D
T
Q
C
K
R
V
G
T
Site 19
S377
K
F
G
Q
D
L
F
S
K
T
Q
I
L
Y
V
Site 20
T415
H
Y
G
H
R
E
K
T
Y
S
E
C
E
D
G
Site 21
Y416
Y
G
H
R
E
K
T
Y
S
E
C
E
D
G
T
Site 22
S417
G
H
R
E
K
T
Y
S
E
C
E
D
G
T
Y
Site 23
T423
Y
S
E
C
E
D
G
T
Y
S
P
E
I
S
W
Site 24
Y424
S
E
C
E
D
G
T
Y
S
P
E
I
S
W
H
Site 25
S425
E
C
E
D
G
T
Y
S
P
E
I
S
W
H
H
Site 26
T436
S
W
H
H
R
K
G
T
K
G
S
E
D
S
P
Site 27
S442
G
T
K
G
S
E
D
S
P
P
K
H
A
G
N
Site 28
S452
K
H
A
G
N
N
E
S
H
S
S
R
R
R
N
Site 29
S454
A
G
N
N
E
S
H
S
S
R
R
R
N
R
H
Site 30
S455
G
N
N
E
S
H
S
S
R
R
R
N
R
H
S
Site 31
S462
S
R
R
R
N
R
H
S
K
S
K
V
T
N
G
Site 32
S464
R
R
N
R
H
S
K
S
K
V
T
N
G
V
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation