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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
LHX1
Full Name:
LIM/homeobox protein Lhx1
Alias:
Homeobox protein Lim-1
Type:
Mass (Da):
44808
Number AA:
406
UniProt ID:
P48742
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y50
F
S
R
E
G
K
L
Y
C
K
N
D
F
F
R
Site 2
S71
A
G
C
A
Q
G
I
S
P
S
D
L
V
R
R
Site 3
S73
C
A
Q
G
I
S
P
S
D
L
V
R
R
A
R
Site 4
S81
D
L
V
R
R
A
R
S
K
V
F
H
L
N
C
Site 5
Y105
L
S
T
G
E
E
L
Y
I
I
D
E
N
K
F
Site 6
Y118
K
F
V
C
K
E
D
Y
L
S
N
S
S
V
A
Site 7
S120
V
C
K
E
D
Y
L
S
N
S
S
V
A
K
E
Site 8
S122
K
E
D
Y
L
S
N
S
S
V
A
K
E
N
S
Site 9
S123
E
D
Y
L
S
N
S
S
V
A
K
E
N
S
L
Site 10
S129
S
S
V
A
K
E
N
S
L
H
S
A
T
T
G
Site 11
S132
A
K
E
N
S
L
H
S
A
T
T
G
S
D
P
Site 12
T135
N
S
L
H
S
A
T
T
G
S
D
P
S
L
S
Site 13
S137
L
H
S
A
T
T
G
S
D
P
S
L
S
P
D
Site 14
S140
A
T
T
G
S
D
P
S
L
S
P
D
S
Q
D
Site 15
S142
T
G
S
D
P
S
L
S
P
D
S
Q
D
P
S
Site 16
S145
D
P
S
L
S
P
D
S
Q
D
P
S
Q
D
D
Site 17
S149
S
P
D
S
Q
D
P
S
Q
D
D
A
K
D
S
Site 18
S156
S
Q
D
D
A
K
D
S
E
S
A
N
V
S
D
Site 19
S158
D
D
A
K
D
S
E
S
A
N
V
S
D
K
E
Site 20
S162
D
S
E
S
A
N
V
S
D
K
E
A
G
S
N
Site 21
T185
A
K
R
R
G
P
R
T
T
I
K
A
K
Q
L
Site 22
T186
K
R
R
G
P
R
T
T
I
K
A
K
Q
L
E
Site 23
T202
L
K
A
A
F
A
A
T
P
K
P
T
R
H
I
Site 24
S242
E
R
R
M
K
Q
L
S
A
L
G
A
R
R
H
Site 25
S254
R
R
H
A
F
F
R
S
P
R
R
M
R
P
L
Site 26
S277
L
I
P
N
G
P
F
S
F
Y
G
D
Y
Q
S
Site 27
Y279
P
N
G
P
F
S
F
Y
G
D
Y
Q
S
E
Y
Site 28
Y282
P
F
S
F
Y
G
D
Y
Q
S
E
Y
Y
G
P
Site 29
S284
S
F
Y
G
D
Y
Q
S
E
Y
Y
G
P
G
G
Site 30
Y286
Y
G
D
Y
Q
S
E
Y
Y
G
P
G
G
N
Y
Site 31
Y287
G
D
Y
Q
S
E
Y
Y
G
P
G
G
N
Y
D
Site 32
Y293
Y
Y
G
P
G
G
N
Y
D
F
F
P
Q
G
P
Site 33
S302
F
F
P
Q
G
P
P
S
S
Q
A
Q
T
P
V
Site 34
S303
F
P
Q
G
P
P
S
S
Q
A
Q
T
P
V
D
Site 35
T307
P
P
S
S
Q
A
Q
T
P
V
D
L
P
F
V
Site 36
S316
V
D
L
P
F
V
P
S
S
G
P
S
G
T
P
Site 37
S317
D
L
P
F
V
P
S
S
G
P
S
G
T
P
L
Site 38
T322
P
S
S
G
P
S
G
T
P
L
G
G
L
E
H
Site 39
S337
P
L
P
G
H
H
P
S
S
E
A
Q
R
F
T
Site 40
S338
L
P
G
H
H
P
S
S
E
A
Q
R
F
T
D
Site 41
T344
S
S
E
A
Q
R
F
T
D
I
L
A
H
P
P
Site 42
S354
L
A
H
P
P
G
D
S
P
S
P
E
P
S
L
Site 43
S356
H
P
P
G
D
S
P
S
P
E
P
S
L
P
G
Site 44
S360
D
S
P
S
P
E
P
S
L
P
G
P
L
H
S
Site 45
S369
P
G
P
L
H
S
M
S
A
E
V
F
G
P
S
Site 46
S376
S
A
E
V
F
G
P
S
P
P
F
S
S
L
S
Site 47
S380
F
G
P
S
P
P
F
S
S
L
S
V
N
G
G
Site 48
S381
G
P
S
P
P
F
S
S
L
S
V
N
G
G
A
Site 49
S383
S
P
P
F
S
S
L
S
V
N
G
G
A
S
Y
Site 50
S389
L
S
V
N
G
G
A
S
Y
G
N
H
L
S
H
Site 51
Y390
S
V
N
G
G
A
S
Y
G
N
H
L
S
H
P
Site 52
S395
A
S
Y
G
N
H
L
S
H
P
P
E
M
N
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation