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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
MARCKSL1
Full Name:
MARCKS-related protein
Alias:
MacMARCKS; Mac-MARCKS; MLP; MRP
Type:
Unknown, protein kinase C/calmodulin signaling
Mass (Da):
19529
Number AA:
195
UniProt ID:
P49006
International Prot ID:
IPI00641181
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005886
GO:0016020
GO:0044464
Uniprot
OncoNet
Molecular Function:
GO:0005516
GO:0005515
GO:0005516
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S3
_
_
_
_
_
M
G
S
Q
S
S
K
A
P
R
Site 2
S6
_
_
M
G
S
Q
S
S
K
A
P
R
G
D
V
Site 3
T14
K
A
P
R
G
D
V
T
A
E
E
A
A
G
A
Site 4
S22
A
E
E
A
A
G
A
S
P
A
K
A
N
G
Q
Site 5
S36
Q
E
N
G
H
V
K
S
N
G
D
L
S
P
K
Site 6
S41
V
K
S
N
G
D
L
S
P
K
G
E
G
E
S
Site 7
S48
S
P
K
G
E
G
E
S
P
P
V
N
G
T
D
Site 8
T54
E
S
P
P
V
N
G
T
D
E
A
A
G
A
T
Site 9
S71
A
I
E
P
A
P
P
S
Q
G
A
E
A
K
G
Site 10
T85
G
E
V
P
P
K
E
T
P
K
K
K
K
K
F
Site 11
S93
P
K
K
K
K
K
F
S
F
K
K
P
F
K
L
Site 12
S101
F
K
K
P
F
K
L
S
G
L
S
F
K
R
N
Site 13
S104
P
F
K
L
S
G
L
S
F
K
R
N
R
K
E
Site 14
S116
R
K
E
G
G
G
D
S
S
A
S
S
P
T
E
Site 15
S117
K
E
G
G
G
D
S
S
A
S
S
P
T
E
E
Site 16
S119
G
G
G
D
S
S
A
S
S
P
T
E
E
E
Q
Site 17
S120
G
G
D
S
S
A
S
S
P
T
E
E
E
Q
E
Site 18
T122
D
S
S
A
S
S
P
T
E
E
E
Q
E
Q
G
Site 19
S135
Q
G
E
I
G
A
C
S
D
E
G
T
A
Q
E
Site 20
T139
G
A
C
S
D
E
G
T
A
Q
E
G
K
A
A
Site 21
T148
Q
E
G
K
A
A
A
T
P
E
S
Q
E
P
Q
Site 22
S151
K
A
A
A
T
P
E
S
Q
E
P
Q
A
K
G
Site 23
S162
Q
A
K
G
A
E
A
S
A
A
S
E
E
E
A
Site 24
S165
G
A
E
A
S
A
A
S
E
E
E
A
G
P
Q
Site 25
T174
E
E
A
G
P
Q
A
T
E
P
S
T
P
S
G
Site 26
S177
G
P
Q
A
T
E
P
S
T
P
S
G
P
E
S
Site 27
T178
P
Q
A
T
E
P
S
T
P
S
G
P
E
S
G
Site 28
S180
A
T
E
P
S
T
P
S
G
P
E
S
G
P
T
Site 29
S184
S
T
P
S
G
P
E
S
G
P
T
P
A
S
A
Site 30
T187
S
G
P
E
S
G
P
T
P
A
S
A
E
Q
N
Site 31
S190
E
S
G
P
T
P
A
S
A
E
Q
N
E
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation