KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
DNASE1L1
Full Name:
Deoxyribonuclease-1-like 1
Alias:
DNase X;Deoxyribonuclease I-like 1;Muscle-specific DNase I-like;XIB
Type:
Mass (Da):
33893
Number AA:
302
UniProt ID:
P49184
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T30
A
F
N
A
Q
R
L
T
L
A
K
V
A
R
E
Site 2
S79
E
L
N
R
F
D
G
S
G
P
Y
S
T
L
S
Site 3
Y82
R
F
D
G
S
G
P
Y
S
T
L
S
S
P
Q
Site 4
S83
F
D
G
S
G
P
Y
S
T
L
S
S
P
Q
L
Site 5
T84
D
G
S
G
P
Y
S
T
L
S
S
P
Q
L
G
Site 6
S86
S
G
P
Y
S
T
L
S
S
P
Q
L
G
R
S
Site 7
S87
G
P
Y
S
T
L
S
S
P
Q
L
G
R
S
T
Site 8
S93
S
S
P
Q
L
G
R
S
T
Y
M
E
T
Y
V
Site 9
T94
S
P
Q
L
G
R
S
T
Y
M
E
T
Y
V
Y
Site 10
Y95
P
Q
L
G
R
S
T
Y
M
E
T
Y
V
Y
F
Site 11
Y99
R
S
T
Y
M
E
T
Y
V
Y
F
Y
R
S
H
Site 12
Y101
T
Y
M
E
T
Y
V
Y
F
Y
R
S
H
K
T
Site 13
Y103
M
E
T
Y
V
Y
F
Y
R
S
H
K
T
Q
V
Site 14
T108
Y
F
Y
R
S
H
K
T
Q
V
L
S
S
Y
V
Site 15
Y114
K
T
Q
V
L
S
S
Y
V
Y
N
D
E
D
D
Site 16
T150
V
L
V
P
L
H
T
T
P
K
A
V
E
K
E
Site 17
Y162
E
K
E
L
N
A
L
Y
D
V
F
L
E
V
S
Site 18
S189
D
F
N
A
D
C
A
S
L
T
K
K
R
L
D
Site 19
T216
V
I
A
D
G
E
D
T
T
V
R
A
S
T
H
Site 20
T217
I
A
D
G
E
D
T
T
V
R
A
S
T
H
C
Site 21
S221
E
D
T
T
V
R
A
S
T
H
C
T
Y
D
R
Site 22
T222
D
T
T
V
R
A
S
T
H
C
T
Y
D
R
V
Site 23
T225
V
R
A
S
T
H
C
T
Y
D
R
V
V
L
H
Site 24
Y226
R
A
S
T
H
C
T
Y
D
R
V
V
L
H
G
Site 25
S238
L
H
G
E
R
C
R
S
L
L
H
T
A
A
A
Site 26
S251
A
A
F
D
F
P
T
S
F
Q
L
T
E
E
E
Site 27
T255
F
P
T
S
F
Q
L
T
E
E
E
A
L
N
I
Site 28
Y266
A
L
N
I
S
D
H
Y
P
V
E
V
E
L
K
Site 29
S275
V
E
V
E
L
K
L
S
Q
A
H
S
V
Q
P
Site 30
S279
L
K
L
S
Q
A
H
S
V
Q
P
L
S
L
T
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation