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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ALDH9A1
Full Name:
4-trimethylaminobutyraldehyde dehydrogenase
Alias:
AL9A1; Aldehyde dehydrogenase 9A1; Aldehyde dehydrogenase E3 isozyme; Aldehyde dehydrogenase family 9 member A1; ALDH4; ALDH7; ALDH9; E3; EC 1.2.1.19; EC 1.2.1.3; EC 1.2.1.47; Gamma-aminobutyraldehyde dehydrogenase; R-aminobutyraldehyde dehydrogenase; TMABADH
Type:
Enzyme - Oxidoreductase; Lipid Metabolism group, Bile acid biosynthesis family, Fatty acid metabolism family, Glycerolipid metabolism family, Carbohydrate Metabolism group, Ascorbate and aldarate metabolism family, glycolysis:gluconeogenesis family, Propa
Mass (Da):
53802
Number AA:
494
UniProt ID:
P49189
International Prot ID:
IPI00873817
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
GO:0005737
GO:0005829
Uniprot
OncoNet
Molecular Function:
GO:0003824
GO:0004029
GO:0016491
PhosphoSite+
KinaseNET
Biological Process:
GO:0006081
GO:0006082
GO:0006091
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S2
_
_
_
_
_
_
M
S
T
G
T
F
V
V
S
Site 2
S9
S
T
G
T
F
V
V
S
Q
P
L
N
Y
R
G
Site 3
S66
K
A
A
F
K
I
W
S
Q
K
S
G
M
E
R
Site 4
S102
E
C
I
N
N
G
K
S
I
F
E
A
R
L
D
Site 5
S138
H
I
Q
L
P
G
G
S
F
G
Y
T
R
R
E
Site 6
Y141
L
P
G
G
S
F
G
Y
T
R
R
E
P
L
G
Site 7
T142
P
G
G
S
F
G
Y
T
R
R
E
P
L
G
V
Site 8
S229
H
P
D
V
A
K
V
S
F
T
G
S
V
P
T
Site 9
T252
A
K
G
I
K
P
V
T
L
E
L
G
G
K
S
Site 10
T325
G
D
P
L
L
E
D
T
R
M
G
P
L
I
N
Site 11
Y360
V
L
C
G
G
D
I
Y
V
P
E
D
P
K
L
Site 12
Y371
D
P
K
L
K
D
G
Y
Y
M
R
P
C
V
L
Site 13
Y372
P
K
L
K
D
G
Y
Y
M
R
P
C
V
L
T
Site 14
Y460
V
E
L
P
F
G
G
Y
K
K
S
G
F
G
R
Site 15
S463
P
F
G
G
Y
K
K
S
G
F
G
R
E
N
G
Site 16
T473
G
R
E
N
G
R
V
T
I
E
Y
Y
S
Q
L
Site 17
Y476
N
G
R
V
T
I
E
Y
Y
S
Q
L
K
T
V
Site 18
T482
E
Y
Y
S
Q
L
K
T
V
C
V
E
M
G
D
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation