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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
RPIA
Full Name:
Ribose-5-phosphate isomerase
Alias:
EC=5.3.1.6; Phosphoriboisomerase; RPI
Type:
Enzyme, isomerase
Mass (Da):
33269
Number AA:
311
UniProt ID:
P49247
International Prot ID:
IPI00026513
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005622
GO:0005829
GO:0044424
Uniprot
OncoNet
Molecular Function:
GO:0003824
GO:0004751
GO:0016853
PhosphoSite+
KinaseNET
Biological Process:
GO:0005975
GO:0005996
GO:0006066
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S8
M
Q
R
P
G
P
F
S
T
L
Y
G
R
V
L
Site 2
T9
Q
R
P
G
P
F
S
T
L
Y
G
R
V
L
A
Site 3
S27
G
R
A
G
G
A
A
S
G
G
G
G
N
S
W
Site 4
S33
A
S
G
G
G
G
N
S
W
D
L
P
G
S
H
Site 5
S39
N
S
W
D
L
P
G
S
H
V
R
L
P
G
R
Site 6
S49
R
L
P
G
R
A
Q
S
G
T
R
G
G
A
G
Site 7
T51
P
G
R
A
Q
S
G
T
R
G
G
A
G
N
T
Site 8
S59
R
G
G
A
G
N
T
S
T
S
C
G
D
S
N
Site 9
T60
G
G
A
G
N
T
S
T
S
C
G
D
S
N
S
Site 10
S61
G
A
G
N
T
S
T
S
C
G
D
S
N
S
I
Site 11
S65
T
S
T
S
C
G
D
S
N
S
I
C
P
A
P
Site 12
S67
T
S
C
G
D
S
N
S
I
C
P
A
P
S
T
Site 13
S73
N
S
I
C
P
A
P
S
T
M
S
K
A
E
E
Site 14
T74
S
I
C
P
A
P
S
T
M
S
K
A
E
E
A
Site 15
S104
N
Q
V
L
G
I
G
S
G
S
T
I
V
H
A
Site 16
S106
V
L
G
I
G
S
G
S
T
I
V
H
A
V
Q
Site 17
S147
L
Q
Y
G
L
T
L
S
D
L
D
R
H
P
E
Site 18
T180
K
G
G
G
G
C
L
T
Q
E
K
I
V
A
G
Site 19
S202
I
A
D
F
R
K
D
S
K
N
L
G
D
Q
W
Site 20
T273
H
K
W
S
E
V
N
T
A
I
K
M
I
P
G
Site 21
Y295
I
N
M
A
E
R
V
Y
F
G
M
Q
D
G
S
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation