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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
LMAN1
Full Name:
Protein ERGIC-53
Alias:
ER-Golgi intermediate compartment 53 kDa protein;Gp58;Intracellular mannose-specific lectin MR60;Lectin mannose-binding 1
Type:
Mass (Da):
57549
Number AA:
510
UniProt ID:
P49257
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y48
L
P
H
R
R
F
E
Y
K
Y
S
F
K
G
P
Site 2
Y50
H
R
R
F
E
Y
K
Y
S
F
K
G
P
H
L
Site 3
S51
R
R
F
E
Y
K
Y
S
F
K
G
P
H
L
V
Site 4
S60
K
G
P
H
L
V
Q
S
D
G
T
V
P
F
W
Site 5
T63
H
L
V
Q
S
D
G
T
V
P
F
W
A
H
A
Site 6
S77
A
G
N
A
I
P
S
S
D
Q
I
R
V
A
P
Site 7
S85
D
Q
I
R
V
A
P
S
L
K
S
Q
R
G
S
Site 8
S88
R
V
A
P
S
L
K
S
Q
R
G
S
V
W
T
Site 9
S92
S
L
K
S
Q
R
G
S
V
W
T
K
T
K
A
Site 10
T109
E
N
W
E
V
E
V
T
F
R
V
T
G
R
G
Site 11
Y127
A
D
G
L
A
I
W
Y
A
E
N
Q
G
L
E
Site 12
S153
G
V
G
I
F
F
D
S
F
D
N
D
G
K
K
Site 13
Y176
G
N
N
G
Q
I
H
Y
D
H
Q
N
D
G
A
Site 14
S184
D
H
Q
N
D
G
A
S
Q
A
L
A
S
C
Q
Site 15
Y199
R
D
F
R
N
K
P
Y
P
V
R
A
K
I
T
Site 16
Y207
P
V
R
A
K
I
T
Y
Y
Q
N
T
L
T
V
Site 17
Y208
V
R
A
K
I
T
Y
Y
Q
N
T
L
T
V
M
Site 18
T221
V
M
I
N
N
G
F
T
P
D
K
N
D
Y
E
Site 19
Y227
F
T
P
D
K
N
D
Y
E
F
C
A
K
V
E
Site 20
T268
S
F
L
T
F
Q
L
T
E
P
G
K
E
P
P
Site 21
T276
E
P
G
K
E
P
P
T
P
D
K
E
I
S
E
Site 22
S282
P
T
P
D
K
E
I
S
E
K
E
K
E
K
Y
Site 23
Y289
S
E
K
E
K
E
K
Y
Q
E
E
F
E
H
F
Site 24
S325
P
A
E
E
I
F
E
S
V
G
D
R
E
L
R
Site 25
Y362
I
L
D
E
Q
R
R
Y
V
S
S
L
T
E
E
Site 26
S364
D
E
Q
R
R
Y
V
S
S
L
T
E
E
I
S
Site 27
S365
E
Q
R
R
Y
V
S
S
L
T
E
E
I
S
K
Site 28
T367
R
R
Y
V
S
S
L
T
E
E
I
S
K
R
G
Site 29
S371
S
S
L
T
E
E
I
S
K
R
G
A
G
M
P
Site 30
T391
I
T
Q
Q
E
L
D
T
V
V
K
T
Q
H
E
Site 31
T395
E
L
D
T
V
V
K
T
Q
H
E
I
L
R
Q
Site 32
S409
Q
V
N
E
M
K
N
S
M
S
E
T
V
R
L
Site 33
S411
N
E
M
K
N
S
M
S
E
T
V
R
L
V
S
Site 34
T413
M
K
N
S
M
S
E
T
V
R
L
V
S
G
M
Site 35
S418
S
E
T
V
R
L
V
S
G
M
Q
H
P
G
S
Site 36
S425
S
G
M
Q
H
P
G
S
A
G
G
V
Y
E
T
Site 37
Y430
P
G
S
A
G
G
V
Y
E
T
T
Q
H
F
I
Site 38
T433
A
G
G
V
Y
E
T
T
Q
H
F
I
D
I
K
Site 39
S500
I
G
Y
I
M
Y
R
S
Q
Q
E
A
A
A
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation