KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
NASP
Full Name:
Nuclear autoantigenic sperm protein
Alias:
DKFZp547F162; FLB7527; FLJ31599; FLJ35510; MGC19722; MGC20372; MGC2297; Nuclear autoantigenic sperm protein (histone-binding); Nuclear autoantigenic sperm protein isoform 2 variant; PRO1999
Type:
Cell cycle regulation
Mass (Da):
85238
Number AA:
788
UniProt ID:
P49321
International Prot ID:
IPI00179953
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005634
GO:0043226
Uniprot
OncoNet
Molecular Function:
GO:0051879
GO:0005515
GO:0031072
PhosphoSite+
KinaseNET
Biological Process:
GO:0006260
GO:0001824
GO:0007049
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S28
I
E
D
V
P
A
P
S
T
S
A
D
K
V
E
Site 2
S30
D
V
P
A
P
S
T
S
A
D
K
V
E
S
L
Site 3
S36
T
S
A
D
K
V
E
S
L
D
V
D
S
E
A
Site 4
S41
V
E
S
L
D
V
D
S
E
A
K
K
L
L
G
Site 5
S71
N
A
F
Q
E
A
A
S
L
L
G
K
K
Y
G
Site 6
Y77
A
S
L
L
G
K
K
Y
G
E
T
A
N
E
C
Site 7
T123
E
E
E
E
G
E
K
T
E
D
E
S
L
V
E
Site 8
S127
G
E
K
T
E
D
E
S
L
V
E
N
N
D
N
Site 9
Y148
E
E
L
R
E
Q
V
Y
D
A
M
G
E
K
E
Site 10
T160
E
K
E
E
A
K
K
T
E
D
K
S
L
A
K
Site 11
S164
A
K
K
T
E
D
K
S
L
A
K
P
E
T
D
Site 12
T170
K
S
L
A
K
P
E
T
D
K
E
Q
D
S
E
Site 13
S176
E
T
D
K
E
Q
D
S
E
M
E
K
G
G
R
Site 14
S189
G
R
E
D
M
D
I
S
K
S
A
E
E
P
Q
Site 15
S191
E
D
M
D
I
S
K
S
A
E
E
P
Q
E
K
Site 16
T202
P
Q
E
K
V
D
L
T
L
D
W
L
T
E
T
Site 17
T207
D
L
T
L
D
W
L
T
E
T
S
E
E
A
K
Site 18
S210
L
D
W
L
T
E
T
S
E
E
A
K
G
G
A
Site 19
T228
G
P
N
E
A
E
V
T
S
G
K
P
E
Q
E
Site 20
S244
P
D
A
E
E
E
K
S
V
S
G
T
D
V
Q
Site 21
S246
A
E
E
E
K
S
V
S
G
T
D
V
Q
E
E
Site 22
T248
E
E
K
S
V
S
G
T
D
V
Q
E
E
C
R
Site 23
S269
K
Q
G
E
V
I
V
S
I
E
E
K
P
K
E
Site 24
T291
V
T
L
E
K
Q
G
T
A
V
E
V
E
A
E
Site 25
S299
A
V
E
V
E
A
E
S
L
D
P
T
V
K
P
Site 26
T303
E
A
E
S
L
D
P
T
V
K
P
V
D
V
G
Site 27
T320
E
P
E
E
K
V
V
T
S
E
N
E
A
G
K
Site 28
S321
P
E
E
K
V
V
T
S
E
N
E
A
G
K
A
Site 29
S344
E
V
P
P
A
E
E
S
P
E
V
T
T
E
A
Site 30
S361
A
S
A
V
E
A
G
S
E
V
S
E
K
P
G
Site 31
S384
D
G
A
V
N
G
P
S
V
V
G
D
Q
T
P
Site 32
T390
P
S
V
V
G
D
Q
T
P
I
E
P
Q
T
S
Site 33
T396
Q
T
P
I
E
P
Q
T
S
I
E
R
L
T
E
Site 34
S397
T
P
I
E
P
Q
T
S
I
E
R
L
T
E
T
Site 35
T402
Q
T
S
I
E
R
L
T
E
T
K
D
G
S
G
Site 36
T404
S
I
E
R
L
T
E
T
K
D
G
S
G
L
E
Site 37
S408
L
T
E
T
K
D
G
S
G
L
E
E
K
V
R
Site 38
S421
V
R
A
K
L
V
P
S
Q
E
E
T
K
L
S
Site 39
T425
L
V
P
S
Q
E
E
T
K
L
S
V
E
E
S
Site 40
S428
S
Q
E
E
T
K
L
S
V
E
E
S
E
A
A
Site 41
S432
T
K
L
S
V
E
E
S
E
A
A
G
D
G
V
Site 42
T441
A
A
G
D
G
V
D
T
K
V
A
Q
G
A
T
Site 43
T448
T
K
V
A
Q
G
A
T
E
K
S
P
E
D
K
Site 44
S451
A
Q
G
A
T
E
K
S
P
E
D
K
V
Q
I
Site 45
T464
Q
I
A
A
N
E
E
T
Q
E
R
E
E
Q
M
Site 46
T477
Q
M
K
E
G
E
E
T
E
G
S
E
E
D
D
Site 47
S480
E
G
E
E
T
E
G
S
E
E
D
D
K
E
N
Site 48
T490
D
D
K
E
N
D
K
T
E
E
M
P
N
D
S
Site 49
S497
T
E
E
M
P
N
D
S
V
L
E
N
K
S
L
Site 50
S503
D
S
V
L
E
N
K
S
L
Q
E
N
E
E
E
Site 51
T534
I
I
F
K
R
Q
E
T
K
E
A
Q
L
Y
A
Site 52
Y540
E
T
K
E
A
Q
L
Y
A
A
Q
A
H
L
K
Site 53
Y558
V
S
V
E
S
E
N
Y
V
Q
A
V
E
E
F
Site 54
S567
Q
A
V
E
E
F
Q
S
C
L
N
L
Q
E
Q
Site 55
Y575
C
L
N
L
Q
E
Q
Y
L
E
A
H
D
R
L
Site 56
T586
H
D
R
L
L
A
E
T
H
Y
Q
L
G
L
A
Site 57
Y588
R
L
L
A
E
T
H
Y
Q
L
G
L
A
Y
G
Site 58
Y594
H
Y
Q
L
G
L
A
Y
G
Y
N
S
Q
Y
D
Site 59
S598
G
L
A
Y
G
Y
N
S
Q
Y
D
E
A
V
A
Site 60
Y600
A
Y
G
Y
N
S
Q
Y
D
E
A
V
A
Q
F
Site 61
S610
A
V
A
Q
F
S
K
S
I
E
V
I
E
N
R
Site 62
S631
Q
V
K
E
A
E
G
S
S
A
E
Y
K
K
E
Site 63
S659
K
I
E
D
A
K
E
S
Q
R
S
G
N
V
A
Site 64
T679
A
T
L
V
E
S
S
T
S
G
F
T
P
G
G
Site 65
S680
T
L
V
E
S
S
T
S
G
F
T
P
G
G
G
Site 66
T683
E
S
S
T
S
G
F
T
P
G
G
G
G
S
S
Site 67
S689
F
T
P
G
G
G
G
S
S
V
S
M
I
A
S
Site 68
S690
T
P
G
G
G
G
S
S
V
S
M
I
A
S
R
Site 69
S692
G
G
G
G
S
S
V
S
M
I
A
S
R
K
P
Site 70
S696
S
S
V
S
M
I
A
S
R
K
P
T
D
G
A
Site 71
T700
M
I
A
S
R
K
P
T
D
G
A
S
S
S
N
Site 72
S706
P
T
D
G
A
S
S
S
N
C
V
T
D
I
S
Site 73
T710
A
S
S
S
N
C
V
T
D
I
S
H
L
V
R
Site 74
S713
S
N
C
V
T
D
I
S
H
L
V
R
K
K
R
Site 75
S726
K
R
K
P
E
E
E
S
P
R
K
D
D
A
K
Site 76
S745
E
P
E
V
N
G
G
S
G
D
A
V
P
S
G
Site 77
S751
G
S
G
D
A
V
P
S
G
N
E
V
S
E
N
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation