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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
FMO5
Full Name:
Dimethylaniline monooxygenase [N-oxide-forming] 5
Alias:
Dimethylaniline oxidase 5;Hepatic flavin-containing monooxygenase 5
Type:
Mass (Da):
60221
Number AA:
533
UniProt ID:
P49326
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S54
N
P
E
E
G
R
A
S
I
Y
K
S
V
I
I
Site 2
Y56
E
E
G
R
A
S
I
Y
K
S
V
I
I
N
T
Site 3
S58
G
R
A
S
I
Y
K
S
V
I
I
N
T
S
K
Site 4
Y91
H
N
A
Q
V
L
E
Y
F
R
M
Y
A
K
E
Site 5
Y104
K
E
F
D
L
L
K
Y
I
R
F
K
T
T
V
Site 6
T109
L
K
Y
I
R
F
K
T
T
V
C
S
V
K
K
Site 7
T110
K
Y
I
R
F
K
T
T
V
C
S
V
K
K
Q
Site 8
S113
R
F
K
T
T
V
C
S
V
K
K
Q
P
D
F
Site 9
S160
N
A
H
L
P
L
E
S
F
P
G
I
E
K
F
Site 10
Y171
I
E
K
F
K
G
Q
Y
F
H
S
R
D
Y
K
Site 11
Y177
Q
Y
F
H
S
R
D
Y
K
N
P
E
G
F
T
Site 12
S214
T
A
K
Q
V
F
L
S
T
R
R
G
A
W
I
Site 13
Y230
N
R
V
G
D
Y
G
Y
P
A
D
V
L
F
S
Site 14
Y256
G
Q
S
L
A
N
K
Y
L
E
K
K
I
N
Q
Site 15
S280
K
P
K
H
R
A
L
S
Q
H
P
T
L
N
D
Site 16
T284
R
A
L
S
Q
H
P
T
L
N
D
D
L
P
N
Site 17
T310
N
V
K
E
F
T
E
T
A
A
I
F
E
D
G
Site 18
S342
D
F
P
F
L
E
D
S
V
K
V
V
K
N
K
Site 19
S351
K
V
V
K
N
K
I
S
L
Y
K
K
V
F
P
Site 20
Y353
V
K
N
K
I
S
L
Y
K
K
V
F
P
P
N
Site 21
T390
E
L
Q
G
R
W
A
T
Q
V
F
K
G
L
K
Site 22
T398
Q
V
F
K
G
L
K
T
L
P
S
Q
S
E
M
Site 23
S401
K
G
L
K
T
L
P
S
Q
S
E
M
M
A
E
Site 24
S403
L
K
T
L
P
S
Q
S
E
M
M
A
E
I
S
Site 25
S410
S
E
M
M
A
E
I
S
K
A
Q
E
E
I
D
Site 26
Y420
Q
E
E
I
D
K
R
Y
V
E
S
Q
R
H
T
Site 27
S423
I
D
K
R
Y
V
E
S
Q
R
H
T
I
Q
G
Site 28
T427
Y
V
E
S
Q
R
H
T
I
Q
G
D
Y
I
D
Site 29
Y432
R
H
T
I
Q
G
D
Y
I
D
T
M
E
E
L
Site 30
S451
G
V
R
P
N
L
L
S
L
A
F
T
D
P
K
Site 31
Y473
G
P
C
T
P
I
H
Y
R
V
Q
G
P
G
K
Site 32
T490
G
A
R
K
A
I
L
T
T
D
D
R
I
R
K
Site 33
T501
R
I
R
K
P
L
M
T
R
V
V
E
R
S
S
Site 34
S507
M
T
R
V
V
E
R
S
S
S
M
T
S
T
M
Site 35
S508
T
R
V
V
E
R
S
S
S
M
T
S
T
M
T
Site 36
S509
R
V
V
E
R
S
S
S
M
T
S
T
M
T
I
Site 37
T511
V
E
R
S
S
S
M
T
S
T
M
T
I
G
K
Site 38
S512
E
R
S
S
S
M
T
S
T
M
T
I
G
K
F
Site 39
T513
R
S
S
S
M
T
S
T
M
T
I
G
K
F
M
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation