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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
DHPS
Full Name:
Deoxyhypusine synthase
Alias:
DHS; DHYS; DS; MIG13; Migration-inducing gene 13
Type:
Transferase; Cell cycle regulation; EC 2.5.1.46
Mass (Da):
40971
Number AA:
369
UniProt ID:
P49366
International Prot ID:
IPI00026829
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005829
GO:0044424
GO:0044444
Uniprot
OncoNet
Molecular Function:
GO:0034038
GO:0005515
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0008612
GO:0008284
GO:0050983
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S22
A
A
V
L
K
H
S
S
T
L
P
P
E
S
T
Site 2
T23
A
V
L
K
H
S
S
T
L
P
P
E
S
T
Q
Site 3
S28
S
S
T
L
P
P
E
S
T
Q
V
R
G
Y
D
Site 4
T29
S
T
L
P
P
E
S
T
Q
V
R
G
Y
D
F
Site 5
Y34
E
S
T
Q
V
R
G
Y
D
F
N
R
G
V
N
Site 6
S78
E
K
K
L
E
P
L
S
Q
D
E
D
Q
H
A
Site 7
T88
E
D
Q
H
A
D
L
T
Q
S
R
R
P
L
T
Site 8
S90
Q
H
A
D
L
T
Q
S
R
R
P
L
T
S
C
Site 9
T95
T
Q
S
R
R
P
L
T
S
C
T
I
F
L
G
Site 10
S96
Q
S
R
R
P
L
T
S
C
T
I
F
L
G
Y
Site 11
S109
G
Y
T
S
N
L
I
S
S
G
I
R
E
T
I
Site 12
S110
Y
T
S
N
L
I
S
S
G
I
R
E
T
I
R
Site 13
T115
I
S
S
G
I
R
E
T
I
R
Y
L
V
Q
H
Site 14
Y118
G
I
R
E
T
I
R
Y
L
V
Q
H
N
M
V
Site 15
S152
P
T
Y
L
G
E
F
S
L
R
G
K
E
L
R
Site 16
T202
N
T
E
G
V
K
W
T
P
S
K
M
I
A
R
Site 17
S204
E
G
V
K
W
T
P
S
K
M
I
A
R
L
G
Site 18
Y222
N
N
P
E
S
V
Y
Y
W
A
Q
K
N
H
I
Site 19
S233
K
N
H
I
P
V
F
S
P
A
L
T
D
G
S
Site 20
Y305
N
G
A
D
Y
A
V
Y
I
N
T
A
Q
E
F
Site 21
S315
T
A
Q
E
F
D
G
S
D
S
G
A
R
P
D
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation