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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
INPP1
Full Name:
Inositol polyphosphate 1-phosphatase
Alias:
EC 3.1.3.57; Inositol polyphosphate-1-phosphatase; INPP; IPP; IPPase
Type:
EC 3.1.3.57; Phosphatase (non-protein); Carbohydrate Metabolism - inositol phosphate
Mass (Da):
43998
Number AA:
399
UniProt ID:
P49441
International Prot ID:
IPI00027139
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0004441
GO:0031403
GO:0000287
PhosphoSite+
KinaseNET
Biological Process:
GO:0006796
GO:0007165
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S81
K
N
I
F
G
E
E
S
N
E
F
T
N
D
W
Site 2
T85
G
E
E
S
N
E
F
T
N
D
W
G
E
K
I
Site 3
T93
N
D
W
G
E
K
I
T
L
R
L
C
S
T
E
Site 4
S98
K
I
T
L
R
L
C
S
T
E
E
E
T
A
E
Site 5
T135
D
V
A
F
T
D
P
T
L
D
S
T
E
I
N
Site 6
S138
F
T
D
P
T
L
D
S
T
E
I
N
V
P
Q
Site 7
T139
T
D
P
T
L
D
S
T
E
I
N
V
P
Q
D
Site 8
Y159
V
D
P
I
D
S
T
Y
Q
Y
I
K
G
S
A
Site 9
Y161
P
I
D
S
T
Y
Q
Y
I
K
G
S
A
D
I
Site 10
S170
K
G
S
A
D
I
K
S
N
Q
G
I
F
P
C
Site 11
T212
F
V
S
R
D
P
N
T
L
R
W
K
G
Q
C
Site 12
Y225
Q
C
Y
W
G
L
S
Y
M
G
T
N
M
H
S
Site 13
S232
Y
M
G
T
N
M
H
S
L
Q
L
T
I
S
R
Site 14
T236
N
M
H
S
L
Q
L
T
I
S
R
R
N
G
S
Site 15
S238
H
S
L
Q
L
T
I
S
R
R
N
G
S
E
T
Site 16
S243
T
I
S
R
R
N
G
S
E
T
H
T
G
N
T
Site 17
T245
S
R
R
N
G
S
E
T
H
T
G
N
T
G
S
Site 18
T247
R
N
G
S
E
T
H
T
G
N
T
G
S
E
A
Site 19
S252
T
H
T
G
N
T
G
S
E
A
A
F
S
P
S
Site 20
S265
P
S
F
S
A
V
I
S
T
S
E
K
E
T
I
Site 21
T271
I
S
T
S
E
K
E
T
I
K
A
A
L
S
R
Site 22
S277
E
T
I
K
A
A
L
S
R
V
C
G
D
R
I
Site 23
S317
D
T
T
F
K
W
D
S
C
A
A
H
A
I
L
Site 24
Y353
L
D
L
P
Q
L
V
Y
H
V
E
N
E
G
A
Site 25
Y375
N
K
G
G
L
I
A
Y
R
S
R
K
R
L
E
Site 26
S377
G
G
L
I
A
Y
R
S
R
K
R
L
E
T
F
Site 27
T383
R
S
R
K
R
L
E
T
F
L
S
L
L
V
Q
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation