PhosphoNET

           
Protein Info 
   
Short Name:  INPP1
Full Name:  Inositol polyphosphate 1-phosphatase
Alias:  EC 3.1.3.57; Inositol polyphosphate-1-phosphatase; INPP; IPP; IPPase
Type:  EC 3.1.3.57; Phosphatase (non-protein); Carbohydrate Metabolism - inositol phosphate
Mass (Da):  43998
Number AA:  399
UniProt ID:  P49441
International Prot ID:  IPI00027139
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:      Uniprot OncoNet
Molecular Function:  GO:0004441  GO:0031403  GO:0000287 PhosphoSite+ KinaseNET
Biological Process:  GO:0006796  GO:0007165   Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S81KNIFGEESNEFTNDW
Site 2T85GEESNEFTNDWGEKI
Site 3T93NDWGEKITLRLCSTE
Site 4S98KITLRLCSTEEETAE
Site 5T135DVAFTDPTLDSTEIN
Site 6S138FTDPTLDSTEINVPQ
Site 7T139TDPTLDSTEINVPQD
Site 8Y159VDPIDSTYQYIKGSA
Site 9Y161PIDSTYQYIKGSADI
Site 10S170KGSADIKSNQGIFPC
Site 11T212FVSRDPNTLRWKGQC
Site 12Y225QCYWGLSYMGTNMHS
Site 13S232YMGTNMHSLQLTISR
Site 14T236NMHSLQLTISRRNGS
Site 15S238HSLQLTISRRNGSET
Site 16S243TISRRNGSETHTGNT
Site 17T245SRRNGSETHTGNTGS
Site 18T247RNGSETHTGNTGSEA
Site 19S252THTGNTGSEAAFSPS
Site 20S265PSFSAVISTSEKETI
Site 21T271ISTSEKETIKAALSR
Site 22S277ETIKAALSRVCGDRI
Site 23S317DTTFKWDSCAAHAIL
Site 24Y353LDLPQLVYHVENEGA
Site 25Y375NKGGLIAYRSRKRLE
Site 26S377GGLIAYRSRKRLETF
Site 27T383RSRKRLETFLSLLVQ
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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