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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
DGK-G
Full Name:
Diacylglycerol kinase gamma
Alias:
DAG kinase gamma; DAGK3; DGKG; DGK-gamma; Diacylglycerol kinase, gamma 90kDa; Diglyceride kinase gamma; Diglyceride kinase gamma;DGK-gamma;DAG kinase gamma
Type:
Kinase, lipid; EC 2.7.1.107; Lipid Metabolism - glycerophospholipid; Lipid Metabolism - glycerolipid
Mass (Da):
88997
Number AA:
791
UniProt ID:
P49619
International Prot ID:
IPI00027658
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0016020
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0005509
GO:0004143
PhosphoSite+
KinaseNET
Biological Process:
GO:0007205
GO:0007242
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S8
M
G
E
E
R
W
V
S
L
T
P
E
E
F
D
Site 2
T10
E
E
R
W
V
S
L
T
P
E
E
F
D
Q
L
Site 3
Y20
E
F
D
Q
L
Q
K
Y
S
E
Y
S
S
K
K
Site 4
S21
F
D
Q
L
Q
K
Y
S
E
Y
S
S
K
K
I
Site 5
S25
Q
K
Y
S
E
Y
S
S
K
K
I
K
D
A
L
Site 6
T33
K
K
I
K
D
A
L
T
E
F
N
E
G
G
S
Site 7
Y44
E
G
G
S
L
K
Q
Y
D
P
H
E
P
I
S
Site 8
Y52
D
P
H
E
P
I
S
Y
D
V
F
K
L
F
M
Site 9
S80
T
H
L
F
L
A
F
S
Q
K
P
R
H
E
T
Site 10
T87
S
Q
K
P
R
H
E
T
S
D
H
P
T
E
G
Site 11
S88
Q
K
P
R
H
E
T
S
D
H
P
T
E
G
A
Site 12
T92
H
E
T
S
D
H
P
T
E
G
A
S
N
S
E
Site 13
S96
D
H
P
T
E
G
A
S
N
S
E
A
N
S
A
Site 14
S98
P
T
E
G
A
S
N
S
E
A
N
S
A
D
T
Site 15
S102
A
S
N
S
E
A
N
S
A
D
T
N
I
Q
N
Site 16
T124
D
E
A
C
A
P
D
T
E
S
N
M
A
E
K
Site 17
S126
A
C
A
P
D
T
E
S
N
M
A
E
K
Q
A
Site 18
T142
A
E
D
Q
V
A
A
T
P
L
E
P
P
V
P
Site 19
S151
L
E
P
P
V
P
R
S
S
S
S
E
S
P
V
Site 20
S152
E
P
P
V
P
R
S
S
S
S
E
S
P
V
V
Site 21
S153
P
P
V
P
R
S
S
S
S
E
S
P
V
V
Y
Site 22
S154
P
V
P
R
S
S
S
S
E
S
P
V
V
Y
L
Site 23
S156
P
R
S
S
S
S
E
S
P
V
V
Y
L
K
D
Site 24
T173
C
Y
L
S
L
L
E
T
G
R
P
Q
D
K
L
Site 25
Y187
L
E
F
M
F
R
L
Y
D
S
D
E
N
G
L
Site 26
S189
F
M
F
R
L
Y
D
S
D
E
N
G
L
L
D
Site 27
Y213
Q
M
L
H
I
A
Q
Y
L
E
W
D
P
T
E
Site 28
T219
Q
Y
L
E
W
D
P
T
E
L
R
P
I
L
K
Site 29
Y234
E
M
L
Q
G
M
D
Y
D
R
D
G
F
V
S
Site 30
S264
V
L
L
G
M
D
D
S
G
S
K
G
D
G
R
Site 31
S266
L
G
M
D
D
S
G
S
K
G
D
G
R
H
A
Site 32
T324
N
I
P
G
C
V
K
T
Y
S
K
A
K
R
S
Site 33
S326
P
G
C
V
K
T
Y
S
K
A
K
R
S
G
E
Site 34
Y358
C
H
K
S
I
K
C
Y
Q
S
V
T
A
R
H
Site 35
S380
F
H
R
K
C
E
L
S
T
L
C
D
G
G
E
Site 36
T381
H
R
K
C
E
L
S
T
L
C
D
G
G
E
L
Site 37
T402
P
T
S
I
C
P
I
T
R
D
R
P
G
E
K
Site 38
S410
R
D
R
P
G
E
K
S
D
G
C
V
S
A
K
Site 39
S415
E
K
S
D
G
C
V
S
A
K
G
E
L
V
M
Site 40
Y424
K
G
E
L
V
M
Q
Y
K
I
I
P
T
P
G
Site 41
T429
M
Q
Y
K
I
I
P
T
P
G
T
H
P
L
L
Site 42
S443
L
V
L
V
N
P
K
S
G
G
R
Q
G
E
R
Site 43
Y457
R
I
L
R
K
F
H
Y
L
L
N
P
K
Q
V
Site 44
T473
N
L
D
N
G
G
P
T
P
G
L
N
F
F
R
Site 45
T482
G
L
N
F
F
R
D
T
P
D
F
R
V
L
A
Site 46
Y535
C
L
R
W
G
G
G
Y
E
G
G
S
L
T
K
Site 47
S539
G
G
G
Y
E
G
G
S
L
T
K
I
L
K
D
Site 48
Y582
P
Y
S
I
M
N
N
Y
F
S
I
G
V
D
A
Site 49
Y616
R
M
K
N
K
L
W
Y
F
E
F
G
T
S
E
Site 50
T624
F
E
F
G
T
S
E
T
F
A
A
T
C
K
K
Site 51
S683
N
R
A
V
I
R
E
S
R
K
G
V
T
D
P
Site 52
Y720
A
M
E
M
G
Q
I
Y
T
G
L
K
S
A
G
Site 53
S725
Q
I
Y
T
G
L
K
S
A
G
R
R
L
A
Q
Site 54
S735
R
R
L
A
Q
C
A
S
V
T
I
R
T
N
K
Site 55
T737
L
A
Q
C
A
S
V
T
I
R
T
N
K
L
L
Site 56
S778
M
M
G
P
P
Q
K
S
S
F
F
S
L
R
R
Site 57
S779
M
G
P
P
Q
K
S
S
F
F
S
L
R
R
K
Site 58
S782
P
Q
K
S
S
F
F
S
L
R
R
K
S
R
S
Site 59
S787
F
F
S
L
R
R
K
S
R
S
K
D
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation