KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
HOXA1
Full Name:
Homeobox protein Hox-A1
Alias:
Homeobox protein Hox-1F
Type:
Mass (Da):
36641
Number AA:
335
UniProt ID:
P49639
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S8
M
D
N
A
R
M
N
S
F
L
E
Y
P
I
L
Site 2
Y12
R
M
N
S
F
L
E
Y
P
I
L
S
S
G
D
Site 3
S17
L
E
Y
P
I
L
S
S
G
D
S
G
T
C
S
Site 4
S20
P
I
L
S
S
G
D
S
G
T
C
S
A
R
A
Site 5
T22
L
S
S
G
D
S
G
T
C
S
A
R
A
Y
P
Site 6
S24
S
G
D
S
G
T
C
S
A
R
A
Y
P
S
D
Site 7
Y28
G
T
C
S
A
R
A
Y
P
S
D
H
R
I
T
Site 8
S30
C
S
A
R
A
Y
P
S
D
H
R
I
T
T
F
Site 9
T36
P
S
D
H
R
I
T
T
F
Q
S
C
A
V
S
Site 10
S39
H
R
I
T
T
F
Q
S
C
A
V
S
A
N
S
Site 11
S43
T
F
Q
S
C
A
V
S
A
N
S
C
G
G
D
Site 12
T79
H
H
H
P
Q
P
A
T
Y
Q
T
S
G
N
L
Site 13
Y80
H
H
P
Q
P
A
T
Y
Q
T
S
G
N
L
G
Site 14
S89
T
S
G
N
L
G
V
S
Y
S
H
S
S
C
G
Site 15
Y90
S
G
N
L
G
V
S
Y
S
H
S
S
C
G
P
Site 16
S91
G
N
L
G
V
S
Y
S
H
S
S
C
G
P
S
Site 17
S93
L
G
V
S
Y
S
H
S
S
C
G
P
S
Y
G
Site 18
S94
G
V
S
Y
S
H
S
S
C
G
P
S
Y
G
S
Site 19
S98
S
H
S
S
C
G
P
S
Y
G
S
Q
N
F
S
Site 20
Y99
H
S
S
C
G
P
S
Y
G
S
Q
N
F
S
A
Site 21
S101
S
C
G
P
S
Y
G
S
Q
N
F
S
A
P
Y
Site 22
S105
S
Y
G
S
Q
N
F
S
A
P
Y
S
P
Y
A
Site 23
S109
Q
N
F
S
A
P
Y
S
P
Y
A
L
N
Q
E
Site 24
S120
L
N
Q
E
A
D
V
S
G
G
Y
P
Q
C
A
Site 25
Y123
E
A
D
V
S
G
G
Y
P
Q
C
A
P
A
V
Site 26
S132
Q
C
A
P
A
V
Y
S
G
N
L
S
S
P
M
Site 27
S136
A
V
Y
S
G
N
L
S
S
P
M
V
Q
H
H
Site 28
S137
V
Y
S
G
N
L
S
S
P
M
V
Q
H
H
H
Site 29
S156
Y
A
G
G
A
V
G
S
P
Q
Y
I
H
H
S
Site 30
Y159
G
A
V
G
S
P
Q
Y
I
H
H
S
Y
G
Q
Site 31
S170
S
Y
G
Q
E
H
Q
S
L
A
L
A
T
Y
N
Site 32
T175
H
Q
S
L
A
L
A
T
Y
N
N
S
L
S
P
Site 33
Y176
Q
S
L
A
L
A
T
Y
N
N
S
L
S
P
L
Site 34
S179
A
L
A
T
Y
N
N
S
L
S
P
L
H
A
S
Site 35
S181
A
T
Y
N
N
S
L
S
P
L
H
A
S
H
Q
Site 36
S186
S
L
S
P
L
H
A
S
H
Q
E
A
C
R
S
Site 37
S193
S
H
Q
E
A
C
R
S
P
A
S
E
T
S
S
Site 38
S196
E
A
C
R
S
P
A
S
E
T
S
S
P
A
Q
Site 39
S200
S
P
A
S
E
T
S
S
P
A
Q
T
F
D
W
Site 40
T204
E
T
S
S
P
A
Q
T
F
D
W
M
K
V
K
Site 41
T217
V
K
R
N
P
P
K
T
G
K
V
G
E
Y
G
Site 42
Y223
K
T
G
K
V
G
E
Y
G
Y
L
G
Q
P
N
Site 43
Y253
K
E
F
H
F
N
K
Y
L
T
R
A
R
R
V
Site 44
T255
F
H
F
N
K
Y
L
T
R
A
R
R
V
E
I
Site 45
S265
R
R
V
E
I
A
A
S
L
Q
L
N
E
T
Q
Site 46
T271
A
S
L
Q
L
N
E
T
Q
V
K
I
W
F
Q
Site 47
S296
K
E
G
L
L
P
I
S
P
A
T
P
P
G
N
Site 48
T299
L
L
P
I
S
P
A
T
P
P
G
N
D
E
K
Site 49
S310
N
D
E
K
A
E
E
S
S
E
K
S
S
S
S
Site 50
S311
D
E
K
A
E
E
S
S
E
K
S
S
S
S
P
Site 51
S314
A
E
E
S
S
E
K
S
S
S
S
P
C
V
P
Site 52
S315
E
E
S
S
E
K
S
S
S
S
P
C
V
P
S
Site 53
S316
E
S
S
E
K
S
S
S
S
P
C
V
P
S
P
Site 54
S317
S
S
E
K
S
S
S
S
P
C
V
P
S
P
G
Site 55
S322
S
S
S
P
C
V
P
S
P
G
S
S
T
S
D
Site 56
S325
P
C
V
P
S
P
G
S
S
T
S
D
T
L
T
Site 57
S326
C
V
P
S
P
G
S
S
T
S
D
T
L
T
T
Site 58
S328
P
S
P
G
S
S
T
S
D
T
L
T
T
S
H
Site 59
T330
P
G
S
S
T
S
D
T
L
T
T
S
H
_
_
Site 60
S334
T
S
D
T
L
T
T
S
H
_
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation