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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CTCF
Full Name:
Transcriptional repressor CTCF
Alias:
11 zinc finger transcriptional repressor; 11-zinc finger protein; CCCTC-binding factor; CTCFL paralog
Type:
Transcription protein
Mass (Da):
82785
Number AA:
727
UniProt ID:
P49711
International Prot ID:
IPI00027988
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0000775
GO:0000793
GO:0005730
Uniprot
OncoNet
Molecular Function:
GO:0043035
GO:0010843
GO:0016563
PhosphoSite+
KinaseNET
Biological Process:
GO:0016568
GO:0007059
GO:0045892
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T15
A
I
V
E
E
S
E
T
F
I
K
G
K
E
R
Site 2
T24
I
K
G
K
E
R
K
T
Y
Q
R
R
R
E
G
Site 3
Y25
K
G
K
E
R
K
T
Y
Q
R
R
R
E
G
G
Site 4
T81
K
T
E
V
M
E
G
T
V
A
P
E
A
E
A
Site 5
S143
G
A
Y
E
N
E
V
S
K
E
G
L
A
E
S
Site 6
S150
S
K
E
G
L
A
E
S
E
P
M
I
C
H
T
Site 7
S190
L
P
P
Q
E
D
P
S
W
Q
K
D
P
D
Y
Site 8
Y197
S
W
Q
K
D
P
D
Y
Q
P
P
A
K
K
T
Site 9
T207
P
A
K
K
T
K
K
T
K
K
S
K
L
R
Y
Site 10
S210
K
T
K
K
T
K
K
S
K
L
R
Y
T
E
E
Site 11
Y214
T
K
K
S
K
L
R
Y
T
E
E
G
K
D
V
Site 12
T215
K
K
S
K
L
R
Y
T
E
E
G
K
D
V
D
Site 13
S224
E
G
K
D
V
D
V
S
V
Y
D
F
E
E
E
Site 14
S238
E
Q
Q
E
G
L
L
S
E
V
N
A
E
K
V
Site 15
T265
K
K
K
G
V
K
K
T
F
Q
C
E
L
C
S
Site 16
Y273
F
Q
C
E
L
C
S
Y
T
C
P
R
R
S
N
Site 17
T274
Q
C
E
L
C
S
Y
T
C
P
R
R
S
N
L
Site 18
S279
S
Y
T
C
P
R
R
S
N
L
D
R
H
M
K
Site 19
S287
N
L
D
R
H
M
K
S
H
T
D
E
R
P
H
Site 20
T289
D
R
H
M
K
S
H
T
D
E
R
P
H
K
C
Site 21
T305
L
C
G
R
A
F
R
T
V
T
L
L
R
N
H
Site 22
T307
G
R
A
F
R
T
V
T
L
L
R
N
H
L
N
Site 23
T315
L
L
R
N
H
L
N
T
H
T
G
T
R
P
H
Site 24
T317
R
N
H
L
N
T
H
T
G
T
R
P
H
K
C
Site 25
T319
H
L
N
T
H
T
G
T
R
P
H
K
C
P
D
Site 26
S334
C
D
M
A
F
V
T
S
G
E
L
V
R
H
R
Site 27
Y343
E
L
V
R
H
R
R
Y
K
H
T
H
E
K
P
Site 28
T346
R
H
R
R
Y
K
H
T
H
E
K
P
F
K
C
Site 29
Y358
F
K
C
S
M
C
D
Y
A
S
V
E
V
S
K
Site 30
S360
C
S
M
C
D
Y
A
S
V
E
V
S
K
L
K
Site 31
S364
D
Y
A
S
V
E
V
S
K
L
K
R
H
I
R
Site 32
T374
K
R
H
I
R
S
H
T
G
E
R
P
F
Q
C
Site 33
S382
G
E
R
P
F
Q
C
S
L
C
S
Y
A
S
R
Site 34
Y386
F
Q
C
S
L
C
S
Y
A
S
R
D
T
Y
K
Site 35
Y392
S
Y
A
S
R
D
T
Y
K
L
K
R
H
M
R
Site 36
T400
K
L
K
R
H
M
R
T
H
S
G
E
K
P
Y
Site 37
S402
K
R
H
M
R
T
H
S
G
E
K
P
Y
E
C
Site 38
Y407
T
H
S
G
E
K
P
Y
E
C
Y
I
C
H
A
Site 39
Y410
G
E
K
P
Y
E
C
Y
I
C
H
A
R
F
T
Site 40
T431
M
H
I
L
Q
K
H
T
E
N
V
A
K
F
H
Site 41
S450
D
T
V
I
A
R
K
S
D
L
G
V
H
L
R
Site 42
S461
V
H
L
R
K
Q
H
S
Y
I
E
Q
G
K
K
Site 43
Y462
H
L
R
K
Q
H
S
Y
I
E
Q
G
K
K
C
Site 44
Y471
E
Q
G
K
K
C
R
Y
C
D
A
V
F
H
E
Site 45
S488
A
L
I
Q
H
Q
K
S
H
K
N
E
K
R
F
Site 46
T516
H
M
I
M
H
K
R
T
H
T
G
E
K
P
Y
Site 47
T518
I
M
H
K
R
T
H
T
G
E
K
P
Y
A
C
Site 48
S526
G
E
K
P
Y
A
C
S
H
C
D
K
T
F
R
Site 49
T531
A
C
S
H
C
D
K
T
F
R
Q
K
Q
L
L
Site 50
Y545
L
D
M
H
F
K
R
Y
H
D
P
N
F
V
P
Site 51
S558
V
P
A
A
F
V
C
S
K
C
G
K
T
F
T
Site 52
T565
S
K
C
G
K
T
F
T
R
R
N
T
M
A
R
Site 53
T569
K
T
F
T
R
R
N
T
M
A
R
H
A
D
N
Site 54
S594
N
G
G
E
T
K
K
S
K
R
G
R
K
R
K
Site 55
S604
G
R
K
R
K
M
R
S
K
K
E
D
S
S
D
Site 56
S609
M
R
S
K
K
E
D
S
S
D
S
E
N
A
E
Site 57
S610
R
S
K
K
E
D
S
S
D
S
E
N
A
E
P
Site 58
S612
K
K
E
D
S
S
D
S
E
N
A
E
P
D
L
Site 59
T642
E
P
E
P
Q
P
V
T
P
A
P
P
P
A
K
Site 60
T659
R
G
R
P
P
G
R
T
N
Q
P
K
Q
N
Q
Site 61
T678
I
Q
V
E
D
Q
N
T
G
A
I
E
N
I
I
Site 62
T709
E
E
A
Q
P
A
A
T
D
A
P
N
G
D
L
Site 63
T717
D
A
P
N
G
D
L
T
P
E
M
I
L
S
M
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation