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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
VPS41
Full Name:
Vacuolar protein sorting-associated protein 41 homolog
Alias:
HVSP41; S53; vacuolar assembly protein 41; vacuolar assembly protein VPS41; vacuolar protein sorting 41
Type:
Vesicle protein
Mass (Da):
98536
Number AA:
854
UniProt ID:
P49754
International Prot ID:
IPI00028051
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005798
GO:0030897
GO:0005829
Uniprot
OncoNet
Molecular Function:
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0048193
GO:0006886
GO:0016192
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T9
A
E
A
E
E
Q
E
T
G
S
L
E
E
S
T
Site 2
S11
A
E
E
Q
E
T
G
S
L
E
E
S
T
D
E
Site 3
S15
E
T
G
S
L
E
E
S
T
D
E
S
E
E
E
Site 4
S19
L
E
E
S
T
D
E
S
E
E
E
E
S
E
E
Site 5
S24
D
E
S
E
E
E
E
S
E
E
E
P
K
L
K
Site 6
Y32
E
E
E
P
K
L
K
Y
E
R
L
S
N
G
V
Site 7
S36
K
L
K
Y
E
R
L
S
N
G
V
T
E
I
L
Site 8
T40
E
R
L
S
N
G
V
T
E
I
L
Q
K
D
A
Site 9
Y68
G
T
H
Y
G
K
V
Y
L
L
D
V
Q
G
N
Site 10
S83
I
T
Q
K
F
D
V
S
P
V
K
I
N
Q
I
Site 11
S91
P
V
K
I
N
Q
I
S
L
D
E
S
G
E
H
Site 12
S95
N
Q
I
S
L
D
E
S
G
E
H
M
G
V
C
Site 13
S115
V
Q
V
F
G
L
Y
S
G
E
E
F
H
E
T
Site 14
T122
S
G
E
E
F
H
E
T
F
D
C
P
I
K
I
Site 15
S176
E
G
E
G
N
I
R
S
V
K
W
R
G
H
L
Site 16
T204
I
I
S
K
Q
R
I
T
N
V
P
R
D
D
I
Site 17
S212
N
V
P
R
D
D
I
S
L
R
P
D
M
Y
P
Site 18
Y218
I
S
L
R
P
D
M
Y
P
C
S
L
C
W
K
Site 19
S249
S
V
K
E
R
H
A
S
E
M
R
D
L
P
S
Site 20
S256
S
E
M
R
D
L
P
S
R
Y
V
E
I
V
S
Site 21
Y258
M
R
D
L
P
S
R
Y
V
E
I
V
S
Q
F
Site 22
S263
S
R
Y
V
E
I
V
S
Q
F
E
T
E
F
Y
Site 23
Y286
D
Q
L
V
V
L
S
Y
V
K
E
I
S
E
K
Site 24
T294
V
K
E
I
S
E
K
T
E
R
E
Y
C
A
R
Site 25
Y298
S
E
K
T
E
R
E
Y
C
A
R
P
R
L
D
Site 26
S319
E
T
C
E
E
I
S
S
D
A
L
T
V
R
G
Site 27
T323
E
I
S
S
D
A
L
T
V
R
G
F
Q
E
N
Site 28
Y335
Q
E
N
E
C
R
D
Y
H
L
E
Y
S
E
G
Site 29
Y339
C
R
D
Y
H
L
E
Y
S
E
G
E
S
L
F
Site 30
S340
R
D
Y
H
L
E
Y
S
E
G
E
S
L
F
Y
Site 31
S344
L
E
Y
S
E
G
E
S
L
F
Y
I
V
S
P
Site 32
Y347
S
E
G
E
S
L
F
Y
I
V
S
P
R
D
V
Site 33
Y375
W
L
L
E
K
K
K
Y
E
E
A
L
M
A
A
Site 34
S385
A
L
M
A
A
E
I
S
Q
K
N
I
K
R
H
Site 35
Y411
H
L
V
E
R
G
D
Y
D
I
A
A
R
K
C
Site 36
Y431
K
N
A
A
L
W
E
Y
E
V
Y
K
F
K
E
Site 37
Y434
A
L
W
E
Y
E
V
Y
K
F
K
E
I
G
Q
Site 38
S446
I
G
Q
L
K
A
I
S
P
Y
L
P
R
G
D
Site 39
Y448
Q
L
K
A
I
S
P
Y
L
P
R
G
D
P
V
Site 40
S471
I
L
H
E
F
L
E
S
D
Y
E
G
F
A
T
Site 41
Y473
H
E
F
L
E
S
D
Y
E
G
F
A
T
L
I
Site 42
T478
S
D
Y
E
G
F
A
T
L
I
R
E
W
P
G
Site 43
Y488
R
E
W
P
G
D
L
Y
N
N
S
V
I
V
Q
Site 44
S491
P
G
D
L
Y
N
N
S
V
I
V
Q
A
V
R
Site 45
S505
R
D
H
L
K
K
D
S
Q
N
K
T
L
L
K
Site 46
T509
K
K
D
S
Q
N
K
T
L
L
K
T
L
A
E
Site 47
T513
Q
N
K
T
L
L
K
T
L
A
E
L
Y
T
Y
Site 48
Y518
L
K
T
L
A
E
L
Y
T
Y
D
K
N
Y
G
Site 49
Y520
T
L
A
E
L
Y
T
Y
D
K
N
Y
G
N
A
Site 50
Y524
L
Y
T
Y
D
K
N
Y
G
N
A
L
E
I
Y
Site 51
Y531
Y
G
N
A
L
E
I
Y
L
T
L
R
H
K
D
Site 52
T533
N
A
L
E
I
Y
L
T
L
R
H
K
D
V
F
Site 53
S551
H
K
H
N
L
F
S
S
I
K
D
K
I
V
L
Site 54
S579
L
D
N
E
D
K
I
S
I
K
K
V
V
E
E
Site 55
Y597
R
P
E
L
Q
H
V
Y
L
H
K
L
F
K
R
Site 56
Y612
D
H
H
K
G
Q
R
Y
H
E
K
Q
I
S
L
Site 57
S618
R
Y
H
E
K
Q
I
S
L
Y
A
E
Y
D
R
Site 58
Y620
H
E
K
Q
I
S
L
Y
A
E
Y
D
R
P
N
Site 59
Y623
Q
I
S
L
Y
A
E
Y
D
R
P
N
L
L
P
Site 60
S635
L
L
P
F
L
R
D
S
T
H
C
P
L
E
K
Site 61
T636
L
P
F
L
R
D
S
T
H
C
P
L
E
K
A
Site 62
T656
Q
R
N
F
V
E
E
T
V
Y
L
L
S
R
M
Site 63
Y658
N
F
V
E
E
T
V
Y
L
L
S
R
M
G
N
Site 64
S661
E
E
T
V
Y
L
L
S
R
M
G
N
S
R
S
Site 65
S668
S
R
M
G
N
S
R
S
A
L
K
M
I
M
E
Site 66
S742
E
I
P
N
L
R
D
S
L
V
K
I
L
Q
D
Site 67
Y750
L
V
K
I
L
Q
D
Y
N
L
Q
I
L
L
R
Site 68
S801
C
L
S
P
I
L
P
S
D
A
A
K
P
F
S
Site 69
S827
K
E
C
L
P
M
P
S
M
N
S
A
A
Q
F
Site 70
S847
A
K
N
R
G
P
G
S
A
I
L
E
M
K
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation