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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
NUP153
Full Name:
Nuclear pore complex protein Nup153
Alias:
153 kDa nucleoporin; HNUP153; N153; NU153; nucleoporin 153kDa; Nucleoporin Nup153
Type:
Transport protein, facilitator
Mass (Da):
153938
Number AA:
1475
UniProt ID:
P49790
International Prot ID:
IPI00292059
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005643
GO:0005654
GO:0005643
Uniprot
OncoNet
Molecular Function:
GO:0003677
GO:0005515
GO:0005215
PhosphoSite+
KinaseNET
Biological Process:
GO:0051028
GO:0015031
GO:0055085
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S3
_
_
_
_
_
M
A
S
G
A
G
G
V
G
G
Site 2
T18
G
G
G
G
K
I
R
T
R
R
C
H
Q
G
P
Site 3
S41
Q
Q
H
Q
G
I
L
S
R
V
T
E
S
V
K
Site 4
Y58
V
P
G
W
L
Q
R
Y
F
N
K
N
E
D
V
Site 5
S67
N
K
N
E
D
V
C
S
C
S
T
D
T
S
E
Site 6
S69
N
E
D
V
C
S
C
S
T
D
T
S
E
V
P
Site 7
T70
E
D
V
C
S
C
S
T
D
T
S
E
V
P
R
Site 8
S73
C
S
C
S
T
D
T
S
E
V
P
R
W
P
E
Site 9
Y88
N
K
E
D
H
L
V
Y
A
D
E
E
S
S
N
Site 10
S93
L
V
Y
A
D
E
E
S
S
N
I
T
D
G
R
Site 11
S94
V
Y
A
D
E
E
S
S
N
I
T
D
G
R
I
Site 12
T97
D
E
E
S
S
N
I
T
D
G
R
I
T
P
E
Site 13
T102
N
I
T
D
G
R
I
T
P
E
P
A
V
S
N
Site 14
S108
I
T
P
E
P
A
V
S
N
T
E
E
P
S
T
Site 15
T110
P
E
P
A
V
S
N
T
E
E
P
S
T
T
S
Site 16
S114
V
S
N
T
E
E
P
S
T
T
S
T
A
S
N
Site 17
T115
S
N
T
E
E
P
S
T
T
S
T
A
S
N
Y
Site 18
T116
N
T
E
E
P
S
T
T
S
T
A
S
N
Y
P
Site 19
S117
T
E
E
P
S
T
T
S
T
A
S
N
Y
P
D
Site 20
T118
E
E
P
S
T
T
S
T
A
S
N
Y
P
D
V
Site 21
S120
P
S
T
T
S
T
A
S
N
Y
P
D
V
L
T
Site 22
Y122
T
T
S
T
A
S
N
Y
P
D
V
L
T
R
P
Site 23
T127
S
N
Y
P
D
V
L
T
R
P
S
L
H
R
S
Site 24
S130
P
D
V
L
T
R
P
S
L
H
R
S
H
L
N
Site 25
S134
T
R
P
S
L
H
R
S
H
L
N
F
S
M
L
Site 26
S139
H
R
S
H
L
N
F
S
M
L
E
S
P
A
L
Site 27
S143
L
N
F
S
M
L
E
S
P
A
L
H
C
Q
P
Site 28
S151
P
A
L
H
C
Q
P
S
T
S
S
A
F
P
I
Site 29
S154
H
C
Q
P
S
T
S
S
A
F
P
I
G
S
S
Site 30
S164
P
I
G
S
S
G
F
S
L
V
K
E
I
K
D
Site 31
S172
L
V
K
E
I
K
D
S
T
S
Q
H
D
D
D
Site 32
S174
K
E
I
K
D
S
T
S
Q
H
D
D
D
N
I
Site 33
S182
Q
H
D
D
D
N
I
S
T
T
S
G
F
S
S
Site 34
T183
H
D
D
D
N
I
S
T
T
S
G
F
S
S
R
Site 35
T184
D
D
D
N
I
S
T
T
S
G
F
S
S
R
A
Site 36
S185
D
D
N
I
S
T
T
S
G
F
S
S
R
A
S
Site 37
S188
I
S
T
T
S
G
F
S
S
R
A
S
D
K
D
Site 38
S189
S
T
T
S
G
F
S
S
R
A
S
D
K
D
I
Site 39
S192
S
G
F
S
S
R
A
S
D
K
D
I
T
V
S
Site 40
T197
R
A
S
D
K
D
I
T
V
S
K
N
T
S
L
Site 41
S199
S
D
K
D
I
T
V
S
K
N
T
S
L
P
P
Site 42
T202
D
I
T
V
S
K
N
T
S
L
P
P
L
W
S
Site 43
S203
I
T
V
S
K
N
T
S
L
P
P
L
W
S
P
Site 44
S209
T
S
L
P
P
L
W
S
P
E
A
E
R
S
H
Site 45
S215
W
S
P
E
A
E
R
S
H
S
L
S
Q
H
T
Site 46
S217
P
E
A
E
R
S
H
S
L
S
Q
H
T
A
T
Site 47
S219
A
E
R
S
H
S
L
S
Q
H
T
A
T
S
S
Site 48
T224
S
L
S
Q
H
T
A
T
S
S
K
K
P
A
F
Site 49
S225
L
S
Q
H
T
A
T
S
S
K
K
P
A
F
N
Site 50
S226
S
Q
H
T
A
T
S
S
K
K
P
A
F
N
L
Site 51
S234
K
K
P
A
F
N
L
S
A
F
G
T
L
S
P
Site 52
T238
F
N
L
S
A
F
G
T
L
S
P
S
L
G
N
Site 53
S240
L
S
A
F
G
T
L
S
P
S
L
G
N
S
S
Site 54
S242
A
F
G
T
L
S
P
S
L
G
N
S
S
I
L
Site 55
S246
L
S
P
S
L
G
N
S
S
I
L
K
T
S
Q
Site 56
S247
S
P
S
L
G
N
S
S
I
L
K
T
S
Q
L
Site 57
T251
G
N
S
S
I
L
K
T
S
Q
L
G
D
S
P
Site 58
S252
N
S
S
I
L
K
T
S
Q
L
G
D
S
P
F
Site 59
S257
K
T
S
Q
L
G
D
S
P
F
Y
P
G
K
T
Site 60
Y260
Q
L
G
D
S
P
F
Y
P
G
K
T
T
Y
G
Site 61
S276
A
A
A
A
V
R
Q
S
K
L
R
N
T
P
Y
Site 62
T281
R
Q
S
K
L
R
N
T
P
Y
Q
A
P
V
R
Site 63
Y283
S
K
L
R
N
T
P
Y
Q
A
P
V
R
R
Q
Site 64
S297
Q
M
K
A
K
Q
L
S
A
Q
S
Y
G
V
T
Site 65
S300
A
K
Q
L
S
A
Q
S
Y
G
V
T
S
S
T
Site 66
Y301
K
Q
L
S
A
Q
S
Y
G
V
T
S
S
T
A
Site 67
S305
A
Q
S
Y
G
V
T
S
S
T
A
R
R
I
L
Site 68
S306
Q
S
Y
G
V
T
S
S
T
A
R
R
I
L
Q
Site 69
T307
S
Y
G
V
T
S
S
T
A
R
R
I
L
Q
S
Site 70
S314
T
A
R
R
I
L
Q
S
L
E
K
M
S
S
P
Site 71
S319
L
Q
S
L
E
K
M
S
S
P
L
A
D
A
K
Site 72
S320
Q
S
L
E
K
M
S
S
P
L
A
D
A
K
R
Site 73
S330
A
D
A
K
R
I
P
S
I
V
S
S
P
L
N
Site 74
S333
K
R
I
P
S
I
V
S
S
P
L
N
S
P
L
Site 75
S334
R
I
P
S
I
V
S
S
P
L
N
S
P
L
D
Site 76
S338
I
V
S
S
P
L
N
S
P
L
D
R
S
G
I
Site 77
S343
L
N
S
P
L
D
R
S
G
I
D
I
T
D
F
Site 78
T348
D
R
S
G
I
D
I
T
D
F
Q
A
K
R
E
Site 79
S359
A
K
R
E
K
V
D
S
Q
Y
P
P
V
Q
R
Site 80
Y361
R
E
K
V
D
S
Q
Y
P
P
V
Q
R
L
M
Site 81
T369
P
P
V
Q
R
L
M
T
P
K
P
V
S
I
A
Site 82
T377
P
K
P
V
S
I
A
T
N
R
S
V
Y
F
K
Site 83
Y382
I
A
T
N
R
S
V
Y
F
K
P
S
L
T
P
Site 84
S386
R
S
V
Y
F
K
P
S
L
T
P
S
G
E
F
Site 85
T388
V
Y
F
K
P
S
L
T
P
S
G
E
F
R
K
Site 86
S390
F
K
P
S
L
T
P
S
G
E
F
R
K
T
N
Site 87
T396
P
S
G
E
F
R
K
T
N
Q
R
I
D
N
K
Site 88
T413
T
G
Y
E
K
N
M
T
P
G
Q
N
R
E
Q
Site 89
S423
Q
N
R
E
Q
R
E
S
G
F
S
Y
P
N
F
Site 90
S426
E
Q
R
E
S
G
F
S
Y
P
N
F
S
L
P
Site 91
Y427
Q
R
E
S
G
F
S
Y
P
N
F
S
L
P
A
Site 92
S440
P
A
A
N
G
L
S
S
G
V
G
G
G
G
G
Site 93
T454
G
K
M
R
R
E
R
T
R
F
V
A
S
K
P
Site 94
T486
I
T
S
S
S
L
P
T
F
N
F
S
S
P
E
Site 95
S490
S
L
P
T
F
N
F
S
S
P
E
I
T
T
S
Site 96
S491
L
P
T
F
N
F
S
S
P
E
I
T
T
S
S
Site 97
T495
N
F
S
S
P
E
I
T
T
S
S
P
S
P
I
Site 98
T496
F
S
S
P
E
I
T
T
S
S
P
S
P
I
N
Site 99
S497
S
S
P
E
I
T
T
S
S
P
S
P
I
N
S
Site 100
S498
S
P
E
I
T
T
S
S
P
S
P
I
N
S
S
Site 101
S500
E
I
T
T
S
S
P
S
P
I
N
S
S
Q
A
Site 102
S504
S
S
P
S
P
I
N
S
S
Q
A
L
T
N
K
Site 103
S505
S
P
S
P
I
N
S
S
Q
A
L
T
N
K
V
Site 104
T509
I
N
S
S
Q
A
L
T
N
K
V
Q
M
T
S
Site 105
T515
L
T
N
K
V
Q
M
T
S
P
S
S
T
G
S
Site 106
S516
T
N
K
V
Q
M
T
S
P
S
S
T
G
S
P
Site 107
S518
K
V
Q
M
T
S
P
S
S
T
G
S
P
M
F
Site 108
S519
V
Q
M
T
S
P
S
S
T
G
S
P
M
F
K
Site 109
T520
Q
M
T
S
P
S
S
T
G
S
P
M
F
K
F
Site 110
S522
T
S
P
S
S
T
G
S
P
M
F
K
F
S
S
Site 111
S528
G
S
P
M
F
K
F
S
S
P
I
V
K
S
T
Site 112
S529
S
P
M
F
K
F
S
S
P
I
V
K
S
T
E
Site 113
T535
S
S
P
I
V
K
S
T
E
A
N
V
L
P
P
Site 114
S560
V
A
K
T
A
E
L
S
G
S
S
S
T
L
E
Site 115
S562
K
T
A
E
L
S
G
S
S
S
T
L
E
P
I
Site 116
T565
E
L
S
G
S
S
S
T
L
E
P
I
I
S
S
Site 117
S571
S
T
L
E
P
I
I
S
S
S
A
H
H
V
T
Site 118
T578
S
S
S
A
H
H
V
T
T
V
N
S
T
N
C
Site 119
T588
N
S
T
N
C
K
K
T
P
P
E
D
C
E
G
Site 120
S607
A
E
I
L
K
E
G
S
V
L
D
I
L
K
S
Site 121
S614
S
V
L
D
I
L
K
S
P
G
F
A
S
P
K
Site 122
S619
L
K
S
P
G
F
A
S
P
K
I
D
S
V
A
Site 123
T630
D
S
V
A
A
Q
P
T
A
T
S
P
V
V
Y
Site 124
T632
V
A
A
Q
P
T
A
T
S
P
V
V
Y
T
R
Site 125
S633
A
A
Q
P
T
A
T
S
P
V
V
Y
T
R
P
Site 126
S644
Y
T
R
P
A
I
S
S
F
S
S
S
G
I
G
Site 127
S655
S
G
I
G
F
G
E
S
L
K
A
G
S
S
W
Site 128
S660
G
E
S
L
K
A
G
S
S
W
Q
C
D
T
C
Site 129
S661
E
S
L
K
A
G
S
S
W
Q
C
D
T
C
L
Site 130
S687
A
C
Q
A
A
K
L
S
P
R
D
T
A
K
Q
Site 131
T691
A
K
L
S
P
R
D
T
A
K
Q
T
G
I
E
Site 132
T699
A
K
Q
T
G
I
E
T
P
N
K
S
G
K
T
Site 133
S703
G
I
E
T
P
N
K
S
G
K
T
T
L
S
A
Site 134
T707
P
N
K
S
G
K
T
T
L
S
A
S
G
T
G
Site 135
S709
K
S
G
K
T
T
L
S
A
S
G
T
G
F
G
Site 136
S711
G
K
T
T
L
S
A
S
G
T
G
F
G
D
K
Site 137
T713
T
T
L
S
A
S
G
T
G
F
G
D
K
F
K
Site 138
T752
C
E
T
P
K
P
G
T
C
V
K
R
A
L
T
Site 139
T769
V
V
S
E
S
A
E
T
M
T
A
S
S
S
S
Site 140
T771
S
E
S
A
E
T
M
T
A
S
S
S
S
C
T
Site 141
S773
S
A
E
T
M
T
A
S
S
S
S
C
T
V
T
Site 142
S775
E
T
M
T
A
S
S
S
S
C
T
V
T
T
G
Site 143
S776
T
M
T
A
S
S
S
S
C
T
V
T
T
G
T
Site 144
T783
S
C
T
V
T
T
G
T
L
G
F
G
D
K
F
Site 145
S815
A
E
D
N
K
C
V
S
C
M
S
E
K
P
G
Site 146
S818
N
K
C
V
S
C
M
S
E
K
P
G
S
S
V
Site 147
S823
C
M
S
E
K
P
G
S
S
V
P
A
S
S
S
Site 148
S824
M
S
E
K
P
G
S
S
V
P
A
S
S
S
S
Site 149
S828
P
G
S
S
V
P
A
S
S
S
S
T
V
P
V
Site 150
S829
G
S
S
V
P
A
S
S
S
S
T
V
P
V
S
Site 151
S842
V
S
L
P
S
G
G
S
L
G
L
E
K
F
K
Site 152
S854
K
F
K
K
P
E
G
S
W
D
C
E
L
C
L
Site 153
S876
T
K
C
L
A
C
E
S
A
K
P
G
T
K
S
Site 154
S883
S
A
K
P
G
T
K
S
G
F
K
G
F
D
T
Site 155
T890
S
G
F
K
G
F
D
T
S
S
S
S
S
N
S
Site 156
S891
G
F
K
G
F
D
T
S
S
S
S
S
N
S
A
Site 157
S892
F
K
G
F
D
T
S
S
S
S
S
N
S
A
A
Site 158
S893
K
G
F
D
T
S
S
S
S
S
N
S
A
A
S
Site 159
S894
G
F
D
T
S
S
S
S
S
N
S
A
A
S
S
Site 160
S895
F
D
T
S
S
S
S
S
N
S
A
A
S
S
S
Site 161
S897
T
S
S
S
S
S
N
S
A
A
S
S
S
F
K
Site 162
S900
S
S
S
N
S
A
A
S
S
S
F
K
F
G
V
Site 163
S901
S
S
N
S
A
A
S
S
S
F
K
F
G
V
S
Site 164
S902
S
N
S
A
A
S
S
S
F
K
F
G
V
S
S
Site 165
S908
S
S
F
K
F
G
V
S
S
S
S
S
G
P
S
Site 166
S909
S
F
K
F
G
V
S
S
S
S
S
G
P
S
Q
Site 167
S910
F
K
F
G
V
S
S
S
S
S
G
P
S
Q
T
Site 168
S911
K
F
G
V
S
S
S
S
S
G
P
S
Q
T
L
Site 169
S912
F
G
V
S
S
S
S
S
G
P
S
Q
T
L
T
Site 170
S915
S
S
S
S
S
G
P
S
Q
T
L
T
S
T
G
Site 171
T917
S
S
S
G
P
S
Q
T
L
T
S
T
G
N
F
Site 172
T919
S
G
P
S
Q
T
L
T
S
T
G
N
F
K
F
Site 173
S920
G
P
S
Q
T
L
T
S
T
G
N
F
K
F
G
Site 174
S937
G
G
F
K
I
G
V
S
S
D
S
G
S
I
N
Site 175
S938
G
F
K
I
G
V
S
S
D
S
G
S
I
N
P
Site 176
S940
K
I
G
V
S
S
D
S
G
S
I
N
P
M
S
Site 177
S942
G
V
S
S
D
S
G
S
I
N
P
M
S
E
G
Site 178
S947
S
G
S
I
N
P
M
S
E
G
F
K
F
S
K
Site 179
S965
D
F
K
F
G
V
S
S
E
S
K
P
E
E
V
Site 180
S986
D
N
F
K
F
G
L
S
S
G
L
S
N
P
V
Site 181
S987
N
F
K
F
G
L
S
S
G
L
S
N
P
V
S
Site 182
T996
L
S
N
P
V
S
L
T
P
F
Q
F
G
V
S
Site 183
S1017
K
K
E
E
L
P
K
S
S
S
A
G
F
S
F
Site 184
S1018
K
E
E
L
P
K
S
S
S
A
G
F
S
F
G
Site 185
S1019
E
E
L
P
K
S
S
S
A
G
F
S
F
G
T
Site 186
S1023
K
S
S
S
A
G
F
S
F
G
T
G
V
I
N
Site 187
S1031
F
G
T
G
V
I
N
S
T
P
A
P
A
N
T
Site 188
T1038
S
T
P
A
P
A
N
T
I
V
T
S
E
N
K
Site 189
S1042
P
A
N
T
I
V
T
S
E
N
K
S
S
F
N
Site 190
S1046
I
V
T
S
E
N
K
S
S
F
N
L
G
T
I
Site 191
S1047
V
T
S
E
N
K
S
S
F
N
L
G
T
I
E
Site 192
T1052
K
S
S
F
N
L
G
T
I
E
T
K
S
A
S
Site 193
T1055
F
N
L
G
T
I
E
T
K
S
A
S
V
A
P
Site 194
S1059
T
I
E
T
K
S
A
S
V
A
P
F
T
C
K
Site 195
T1064
S
A
S
V
A
P
F
T
C
K
T
S
E
A
K
Site 196
T1078
K
K
E
E
M
P
A
T
K
G
G
F
S
F
G
Site 197
S1083
P
A
T
K
G
G
F
S
F
G
N
V
E
P
A
Site 198
T1103
S
V
F
V
L
G
R
T
E
E
K
Q
Q
E
P
Site 199
S1113
K
Q
Q
E
P
V
T
S
T
S
L
V
F
G
K
Site 200
S1115
Q
E
P
V
T
S
T
S
L
V
F
G
K
K
A
Site 201
S1134
P
K
C
Q
P
V
F
S
F
G
N
S
E
Q
T
Site 202
S1138
P
V
F
S
F
G
N
S
E
Q
T
K
D
E
N
Site 203
S1146
E
Q
T
K
D
E
N
S
S
K
S
T
F
S
F
Site 204
S1147
Q
T
K
D
E
N
S
S
K
S
T
F
S
F
S
Site 205
S1149
K
D
E
N
S
S
K
S
T
F
S
F
S
M
T
Site 206
T1150
D
E
N
S
S
K
S
T
F
S
F
S
M
T
K
Site 207
S1152
N
S
S
K
S
T
F
S
F
S
M
T
K
P
S
Site 208
S1154
S
K
S
T
F
S
F
S
M
T
K
P
S
E
K
Site 209
T1156
S
T
F
S
F
S
M
T
K
P
S
E
K
E
S
Site 210
S1159
S
F
S
M
T
K
P
S
E
K
E
S
E
Q
P
Site 211
S1163
T
K
P
S
E
K
E
S
E
Q
P
A
K
A
T
Site 212
S1191
G
A
A
K
P
V
F
S
F
L
N
N
S
S
S
Site 213
S1196
V
F
S
F
L
N
N
S
S
S
S
S
S
T
P
Site 214
S1197
F
S
F
L
N
N
S
S
S
S
S
S
T
P
A
Site 215
S1198
S
F
L
N
N
S
S
S
S
S
S
T
P
A
T
Site 216
S1200
L
N
N
S
S
S
S
S
S
T
P
A
T
S
A
Site 217
S1201
N
N
S
S
S
S
S
S
T
P
A
T
S
A
G
Site 218
T1202
N
S
S
S
S
S
S
T
P
A
T
S
A
G
G
Site 219
T1205
S
S
S
S
T
P
A
T
S
A
G
G
G
I
F
Site 220
S1206
S
S
S
T
P
A
T
S
A
G
G
G
I
F
G
Site 221
S1214
A
G
G
G
I
F
G
S
S
T
S
S
S
N
P
Site 222
S1215
G
G
G
I
F
G
S
S
T
S
S
S
N
P
P
Site 223
T1216
G
G
I
F
G
S
S
T
S
S
S
N
P
P
V
Site 224
S1217
G
I
F
G
S
S
T
S
S
S
N
P
P
V
A
Site 225
S1218
I
F
G
S
S
T
S
S
S
N
P
P
V
A
T
Site 226
S1219
F
G
S
S
T
S
S
S
N
P
P
V
A
T
F
Site 227
T1225
S
S
N
P
P
V
A
T
F
V
F
G
Q
S
S
Site 228
S1231
A
T
F
V
F
G
Q
S
S
N
P
V
S
S
S
Site 229
S1232
T
F
V
F
G
Q
S
S
N
P
V
S
S
S
A
Site 230
S1236
G
Q
S
S
N
P
V
S
S
S
A
F
G
N
T
Site 231
S1238
S
S
N
P
V
S
S
S
A
F
G
N
T
A
E
Site 232
T1243
S
S
S
A
F
G
N
T
A
E
S
S
T
S
Q
Site 233
S1246
A
F
G
N
T
A
E
S
S
T
S
Q
S
L
L
Site 234
S1247
F
G
N
T
A
E
S
S
T
S
Q
S
L
L
F
Site 235
S1249
N
T
A
E
S
S
T
S
Q
S
L
L
F
S
Q
Site 236
S1251
A
E
S
S
T
S
Q
S
L
L
F
S
Q
D
S
Site 237
S1255
T
S
Q
S
L
L
F
S
Q
D
S
K
L
A
T
Site 238
S1258
S
L
L
F
S
Q
D
S
K
L
A
T
T
S
S
Site 239
T1262
S
Q
D
S
K
L
A
T
T
S
S
T
G
T
A
Site 240
S1265
S
K
L
A
T
T
S
S
T
G
T
A
V
T
P
Site 241
S1281
V
F
G
P
G
A
S
S
N
N
T
T
T
S
G
Site 242
T1284
P
G
A
S
S
N
N
T
T
T
S
G
F
G
F
Site 243
T1285
G
A
S
S
N
N
T
T
T
S
G
F
G
F
G
Site 244
S1287
S
S
N
N
T
T
T
S
G
F
G
F
G
A
T
Site 245
T1294
S
G
F
G
F
G
A
T
T
T
S
S
S
A
G
Site 246
T1295
G
F
G
F
G
A
T
T
T
S
S
S
A
G
S
Site 247
T1296
F
G
F
G
A
T
T
T
S
S
S
A
G
S
S
Site 248
S1297
G
F
G
A
T
T
T
S
S
S
A
G
S
S
F
Site 249
S1302
T
T
S
S
S
A
G
S
S
F
V
F
G
T
G
Site 250
S1303
T
S
S
S
A
G
S
S
F
V
F
G
T
G
P
Site 251
S1314
G
T
G
P
S
A
P
S
A
S
P
A
F
G
A
Site 252
S1316
G
P
S
A
P
S
A
S
P
A
F
G
A
N
Q
Site 253
T1324
P
A
F
G
A
N
Q
T
P
T
F
G
Q
S
Q
Site 254
T1326
F
G
A
N
Q
T
P
T
F
G
Q
S
Q
G
A
Site 255
S1330
Q
T
P
T
F
G
Q
S
Q
G
A
S
Q
P
N
Site 256
S1334
F
G
Q
S
Q
G
A
S
Q
P
N
P
P
G
F
Site 257
S1343
P
N
P
P
G
F
G
S
I
S
S
S
T
A
L
Site 258
S1355
T
A
L
F
P
T
G
S
Q
P
A
P
P
T
F
Site 259
T1361
G
S
Q
P
A
P
P
T
F
G
T
V
S
S
S
Site 260
T1364
P
A
P
P
T
F
G
T
V
S
S
S
S
Q
P
Site 261
S1366
P
P
T
F
G
T
V
S
S
S
S
Q
P
P
V
Site 262
S1367
P
T
F
G
T
V
S
S
S
S
Q
P
P
V
F
Site 263
S1368
T
F
G
T
V
S
S
S
S
Q
P
P
V
F
G
Site 264
S1369
F
G
T
V
S
S
S
S
Q
P
P
V
F
G
Q
Site 265
S1379
P
V
F
G
Q
Q
P
S
Q
S
A
F
G
S
G
Site 266
S1381
F
G
Q
Q
P
S
Q
S
A
F
G
S
G
T
T
Site 267
S1385
P
S
Q
S
A
F
G
S
G
T
T
P
N
S
S
Site 268
T1387
Q
S
A
F
G
S
G
T
T
P
N
S
S
S
A
Site 269
T1388
S
A
F
G
S
G
T
T
P
N
S
S
S
A
F
Site 270
S1391
G
S
G
T
T
P
N
S
S
S
A
F
Q
F
G
Site 271
S1392
S
G
T
T
P
N
S
S
S
A
F
Q
F
G
S
Site 272
S1393
G
T
T
P
N
S
S
S
A
F
Q
F
G
S
S
Site 273
S1399
S
S
A
F
Q
F
G
S
S
T
T
N
F
N
F
Site 274
T1407
S
T
T
N
F
N
F
T
N
N
S
P
S
G
V
Site 275
S1410
N
F
N
F
T
N
N
S
P
S
G
V
F
T
F
Site 276
S1412
N
F
T
N
N
S
P
S
G
V
F
T
F
G
A
Site 277
T1416
N
S
P
S
G
V
F
T
F
G
A
N
S
S
T
Site 278
S1422
F
T
F
G
A
N
S
S
T
P
A
A
S
A
Q
Site 279
T1423
T
F
G
A
N
S
S
T
P
A
A
S
A
Q
P
Site 280
S1427
N
S
S
T
P
A
A
S
A
Q
P
S
G
S
G
Site 281
S1431
P
A
A
S
A
Q
P
S
G
S
G
G
F
P
F
Site 282
T1446
N
Q
S
P
A
A
F
T
V
G
S
N
G
K
N
Site 283
S1456
S
N
G
K
N
V
F
S
S
S
G
T
S
F
S
Site 284
S1457
N
G
K
N
V
F
S
S
S
G
T
S
F
S
G
Site 285
S1458
G
K
N
V
F
S
S
S
G
T
S
F
S
G
R
Site 286
T1460
N
V
F
S
S
S
G
T
S
F
S
G
R
K
I
Site 287
S1461
V
F
S
S
S
G
T
S
F
S
G
R
K
I
K
Site 288
S1463
S
S
S
G
T
S
F
S
G
R
K
I
K
T
A
Site 289
T1469
F
S
G
R
K
I
K
T
A
V
R
R
R
K
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation