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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
GAIP
Full Name:
Regulator of G-protein signaling 19
Alias:
GAIP protein; G-alpha interacting protein; GNAI3IP; RGS19; RGSGAIP
Type:
GTPase-activating protein for G protein
Mass (Da):
24636
Number AA:
217
UniProt ID:
P49795
International Prot ID:
IPI00028108
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005794
GO:0031225
GO:0005624
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0004871
PhosphoSite+
KinaseNET
Biological Process:
GO:0007186
GO:0006914
GO:0009968
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S22
E
E
A
D
R
P
P
S
M
S
S
H
D
T
A
Site 2
S24
A
D
R
P
P
S
M
S
S
H
D
T
A
S
P
Site 3
T28
P
S
M
S
S
H
D
T
A
S
P
A
A
P
S
Site 4
S30
M
S
S
H
D
T
A
S
P
A
A
P
S
R
N
Site 5
S35
T
A
S
P
A
A
P
S
R
N
P
C
C
L
C
Site 6
S62
R
R
R
A
W
Q
A
S
R
E
S
K
L
Q
P
Site 7
S65
A
W
Q
A
S
R
E
S
K
L
Q
P
L
P
S
Site 8
S72
S
K
L
Q
P
L
P
S
C
E
V
C
A
T
P
Site 9
T78
P
S
C
E
V
C
A
T
P
S
P
E
E
V
Q
Site 10
S80
C
E
V
C
A
T
P
S
P
E
E
V
Q
S
W
Site 11
S86
P
S
P
E
E
V
Q
S
W
A
Q
S
F
D
K
Site 12
S90
E
V
Q
S
W
A
Q
S
F
D
K
L
M
H
S
Site 13
S97
S
F
D
K
L
M
H
S
P
A
G
R
S
V
F
Site 14
S102
M
H
S
P
A
G
R
S
V
F
R
A
F
L
R
Site 15
T110
V
F
R
A
F
L
R
T
E
Y
S
E
E
N
M
Site 16
Y112
R
A
F
L
R
T
E
Y
S
E
E
N
M
L
F
Site 17
Y143
D
E
K
A
R
L
I
Y
E
D
Y
V
S
I
L
Site 18
Y146
A
R
L
I
Y
E
D
Y
V
S
I
L
S
P
K
Site 19
S148
L
I
Y
E
D
Y
V
S
I
L
S
P
K
E
V
Site 20
S151
E
D
Y
V
S
I
L
S
P
K
E
V
S
L
D
Site 21
S156
I
L
S
P
K
E
V
S
L
D
S
R
V
R
E
Site 22
S159
P
K
E
V
S
L
D
S
R
V
R
E
G
I
N
Site 23
S192
Y
T
L
M
H
R
D
S
Y
P
R
F
L
S
S
Site 24
Y193
T
L
M
H
R
D
S
Y
P
R
F
L
S
S
P
Site 25
S198
D
S
Y
P
R
F
L
S
S
P
T
Y
R
A
L
Site 26
S199
S
Y
P
R
F
L
S
S
P
T
Y
R
A
L
L
Site 27
T201
P
R
F
L
S
S
P
T
Y
R
A
L
L
L
Q
Site 28
Y202
R
F
L
S
S
P
T
Y
R
A
L
L
L
Q
G
Site 29
S211
A
L
L
L
Q
G
P
S
Q
S
S
S
E
A
_
Site 30
S213
L
L
Q
G
P
S
Q
S
S
S
E
A
_
_
_
Site 31
S214
L
Q
G
P
S
Q
S
S
S
E
A
_
_
_
_
Site 32
S215
Q
G
P
S
Q
S
S
S
E
A
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation