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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PPOX
Full Name:
Protoporphyrinogen oxidase
Alias:
Type:
Mass (Da):
50765
Number AA:
477
UniProt ID:
P50336
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S22
L
A
A
S
Y
H
L
S
R
A
P
C
P
P
K
Site 2
S35
P
K
V
V
L
V
E
S
S
E
R
L
G
G
W
Site 3
S45
R
L
G
G
W
I
R
S
V
R
G
P
N
G
A
Site 4
S119
L
R
G
L
L
R
P
S
P
P
F
S
K
P
L
Site 5
S123
L
R
P
S
P
P
F
S
K
P
L
F
W
A
G
Site 6
T135
W
A
G
L
R
E
L
T
K
P
R
G
K
E
P
Site 7
T145
R
G
K
E
P
D
E
T
V
H
S
F
A
Q
R
Site 8
S148
E
P
D
E
T
V
H
S
F
A
Q
R
R
L
G
Site 9
S175
R
G
V
F
A
G
N
S
R
E
L
S
I
R
S
Site 10
S179
A
G
N
S
R
E
L
S
I
R
S
C
F
P
S
Site 11
S182
S
R
E
L
S
I
R
S
C
F
P
S
L
F
Q
Site 12
S186
S
I
R
S
C
F
P
S
L
F
Q
A
E
Q
T
Site 13
T193
S
L
F
Q
A
E
Q
T
H
R
S
I
L
L
G
Site 14
S213
G
R
T
P
Q
P
D
S
A
L
I
R
Q
A
L
Site 15
S225
Q
A
L
A
E
R
W
S
Q
W
S
L
R
G
G
Site 16
S228
A
E
R
W
S
Q
W
S
L
R
G
G
L
E
M
Site 17
S250
H
L
T
S
R
G
V
S
V
L
R
G
Q
P
V
Site 18
S261
G
Q
P
V
C
G
L
S
L
Q
A
E
G
R
W
Site 19
S271
A
E
G
R
W
K
V
S
L
R
D
S
S
L
E
Site 20
S275
W
K
V
S
L
R
D
S
S
L
E
A
D
H
V
Site 21
S276
K
V
S
L
R
D
S
S
L
E
A
D
H
V
I
Site 22
S359
A
F
P
E
Q
D
G
S
P
P
G
L
R
V
T
Site 23
S385
E
A
S
G
C
V
L
S
Q
E
L
F
Q
Q
R
Site 24
T399
R
A
Q
E
A
A
A
T
Q
L
G
L
K
E
M
Site 25
S432
G
H
W
Q
K
L
E
S
A
R
Q
F
L
T
A
Site 26
T438
E
S
A
R
Q
F
L
T
A
H
R
L
P
L
T
Site 27
T445
T
A
H
R
L
P
L
T
L
A
G
A
S
Y
E
Site 28
S469
S
G
R
Q
A
A
V
S
V
L
G
T
E
P
N
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation