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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
GDI2
Full Name:
Rab GDP dissociation inhibitor beta
Alias:
GDI-2; GDIB; GDP dissociation inhibitor 2; Guanosine diphosphate dissociation inhibitor 2; Rab GDI beta; Rab GDP-dissociation; RABGDIB
Type:
G protein regulator, misc.
Mass (Da):
50663
Number AA:
445
UniProt ID:
P50395
International Prot ID:
IPI00031461
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0009986
GO:0005737
GO:0019898
Uniprot
OncoNet
Molecular Function:
GO:0005096
GO:0005093
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0015031
GO:0043087
GO:0007165
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y38
L
H
M
D
R
N
P
Y
Y
G
G
E
S
A
S
Site 2
Y39
H
M
D
R
N
P
Y
Y
G
G
E
S
A
S
I
Site 3
T47
G
G
E
S
A
S
I
T
P
L
E
D
L
Y
K
Site 4
Y53
I
T
P
L
E
D
L
Y
K
R
F
K
I
P
G
Site 5
S61
K
R
F
K
I
P
G
S
P
P
E
S
M
G
R
Site 6
S65
I
P
G
S
P
P
E
S
M
G
R
G
R
D
W
Site 7
Y93
Q
L
V
K
M
L
L
Y
T
E
V
T
R
Y
L
Site 8
T94
L
V
K
M
L
L
Y
T
E
V
T
R
Y
L
D
Site 9
Y99
L
Y
T
E
V
T
R
Y
L
D
F
K
V
T
E
Site 10
T105
R
Y
L
D
F
K
V
T
E
G
S
F
V
Y
K
Site 11
S108
D
F
K
V
T
E
G
S
F
V
Y
K
G
G
K
Site 12
Y111
V
T
E
G
S
F
V
Y
K
G
G
K
I
Y
K
Site 13
Y117
V
Y
K
G
G
K
I
Y
K
V
P
S
T
E
A
Site 14
S121
G
K
I
Y
K
V
P
S
T
E
A
E
A
L
A
Site 15
T122
K
I
Y
K
V
P
S
T
E
A
E
A
L
A
S
Site 16
Y146
R
F
R
K
F
L
V
Y
V
A
N
F
D
E
K
Site 17
T157
F
D
E
K
D
P
R
T
F
E
G
I
D
P
K
Site 18
T166
E
G
I
D
P
K
K
T
T
M
R
D
V
Y
K
Site 19
T167
G
I
D
P
K
K
T
T
M
R
D
V
Y
K
K
Site 20
Y172
K
T
T
M
R
D
V
Y
K
K
F
D
L
G
Q
Site 21
Y192
T
G
H
A
L
A
L
Y
R
T
D
D
Y
L
D
Site 22
Y197
A
L
Y
R
T
D
D
Y
L
D
Q
P
C
Y
E
Site 23
Y203
D
Y
L
D
Q
P
C
Y
E
T
I
N
R
I
K
Site 24
T205
L
D
Q
P
C
Y
E
T
I
N
R
I
K
L
Y
Site 25
Y212
T
I
N
R
I
K
L
Y
S
E
S
L
A
R
Y
Site 26
S213
I
N
R
I
K
L
Y
S
E
S
L
A
R
Y
G
Site 27
S215
R
I
K
L
Y
S
E
S
L
A
R
Y
G
K
S
Site 28
Y219
Y
S
E
S
L
A
R
Y
G
K
S
P
Y
L
Y
Site 29
S222
S
L
A
R
Y
G
K
S
P
Y
L
Y
P
L
Y
Site 30
Y224
A
R
Y
G
K
S
P
Y
L
Y
P
L
Y
G
L
Site 31
Y226
Y
G
K
S
P
Y
L
Y
P
L
Y
G
L
G
E
Site 32
Y229
S
P
Y
L
Y
P
L
Y
G
L
G
E
L
P
Q
Site 33
S242
P
Q
G
F
A
R
L
S
A
I
Y
G
G
T
Y
Site 34
Y249
S
A
I
Y
G
G
T
Y
M
L
N
K
P
I
E
Site 35
S270
G
K
V
I
G
V
K
S
E
G
E
I
A
R
C
Site 36
S285
K
Q
L
I
C
D
P
S
Y
V
K
D
R
V
E
Site 37
Y286
Q
L
I
C
D
P
S
Y
V
K
D
R
V
E
K
Site 38
Y333
V
N
R
K
S
D
I
Y
V
C
M
I
S
F
A
Site 39
Y349
N
V
A
A
Q
G
K
Y
I
A
I
V
S
T
T
Site 40
S354
G
K
Y
I
A
I
V
S
T
T
V
E
T
K
E
Site 41
T355
K
Y
I
A
I
V
S
T
T
V
E
T
K
E
P
Site 42
S382
P
I
E
Q
K
F
V
S
I
S
D
L
L
V
P
Site 43
T394
L
V
P
K
D
L
G
T
E
S
Q
I
F
I
S
Site 44
S396
P
K
D
L
G
T
E
S
Q
I
F
I
S
R
T
Site 45
T403
S
Q
I
F
I
S
R
T
Y
D
A
T
T
H
F
Site 46
Y404
Q
I
F
I
S
R
T
Y
D
A
T
T
H
F
E
Site 47
T407
I
S
R
T
Y
D
A
T
T
H
F
E
T
T
C
Site 48
T408
S
R
T
Y
D
A
T
T
H
F
E
T
T
C
D
Site 49
Y421
C
D
D
I
K
N
I
Y
K
R
M
T
G
S
E
Site 50
T425
K
N
I
Y
K
R
M
T
G
S
E
F
D
F
E
Site 51
S427
I
Y
K
R
M
T
G
S
E
F
D
F
E
E
M
Site 52
Y442
K
R
K
K
N
D
I
Y
G
E
D
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation