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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SERPINB8
Full Name:
Serpin B8
Alias:
Cytoplasmic antiproteinase 2;Peptidase inhibitor 8
Type:
Mass (Da):
42767
Number AA:
374
UniProt ID:
P50452
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S25
I
L
G
E
E
D
N
S
R
N
V
F
F
S
P
Site 2
S31
N
S
R
N
V
F
F
S
P
M
S
I
S
S
A
Site 3
T50
F
M
G
A
K
G
S
T
A
A
Q
M
S
Q
A
Site 4
S55
G
S
T
A
A
Q
M
S
Q
A
L
C
L
Y
K
Site 5
Y61
M
S
Q
A
L
C
L
Y
K
D
G
D
I
H
R
Site 6
S72
D
I
H
R
G
F
Q
S
L
L
S
E
V
N
R
Site 7
S75
R
G
F
Q
S
L
L
S
E
V
N
R
T
G
T
Site 8
T80
L
L
S
E
V
N
R
T
G
T
Q
Y
L
L
R
Site 9
T82
S
E
V
N
R
T
G
T
Q
Y
L
L
R
T
A
Site 10
Y84
V
N
R
T
G
T
Q
Y
L
L
R
T
A
N
R
Site 11
T97
N
R
L
F
G
E
K
T
C
D
F
L
P
D
F
Site 12
S120
Q
A
E
L
E
E
L
S
F
A
E
D
T
E
E
Site 13
T125
E
L
S
F
A
E
D
T
E
E
C
R
K
H
I
Site 14
T140
N
D
W
V
A
E
K
T
E
G
K
I
S
E
V
Site 15
S145
E
K
T
E
G
K
I
S
E
V
L
D
A
G
T
Site 16
Y179
N
E
Q
F
D
R
K
Y
T
R
G
M
L
F
K
Site 17
T180
E
Q
F
D
R
K
Y
T
R
G
M
L
F
K
T
Site 18
T187
T
R
G
M
L
F
K
T
N
E
E
K
K
T
V
Site 19
T193
K
T
N
E
E
K
K
T
V
Q
M
M
F
K
E
Site 20
Y220
T
Q
V
L
E
L
P
Y
V
E
E
E
L
S
M
Site 21
T246
A
V
V
E
K
A
L
T
Y
E
K
F
K
A
W
Site 22
S256
K
F
K
A
W
T
N
S
E
K
L
T
K
S
K
Site 23
T260
W
T
N
S
E
K
L
T
K
S
K
V
Q
V
F
Site 24
S262
N
S
E
K
L
T
K
S
K
V
Q
V
F
L
P
Site 25
S276
P
R
L
K
L
E
E
S
Y
D
L
E
P
F
L
Site 26
S300
D
E
A
K
A
D
F
S
G
M
S
T
E
K
N
Site 27
T304
A
D
F
S
G
M
S
T
E
K
N
V
P
L
S
Site 28
S311
T
E
K
N
V
P
L
S
K
V
A
H
K
C
F
Site 29
S338
A
T
A
V
V
R
N
S
R
C
S
R
M
E
P
Site 30
S341
V
V
R
N
S
R
C
S
R
M
E
P
R
F
C
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation