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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PEX5
Full Name:
Peroxisomal targeting signal 1 receptor
Alias:
Peroxin-5; Peroxismore receptor 1; Peroxisomal biogenesis factor 5; Peroxisomal C-terminal targeting signal import receptor; Peroxisome receptor 1; PTS1 receptor; PTS1-BP; PTS1R; PXR1
Type:
Membrane protein, integral; Receptor, protein translocating
Mass (Da):
70865
Number AA:
639
UniProt ID:
P50542
International Prot ID:
IPI00032931
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005829
GO:0019898
GO:0005782
Uniprot
OncoNet
Molecular Function:
GO:0005052
GO:0008022
GO:0047485
PhosphoSite+
KinaseNET
Biological Process:
GO:0016561
GO:0006625
GO:0051262
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T25
M
K
L
A
G
H
F
T
Q
D
K
A
L
R
Q
Site 2
S47
W
P
P
G
A
P
A
S
E
A
A
S
K
P
L
Site 3
S58
S
K
P
L
G
V
A
S
E
D
E
L
V
A
E
Site 4
T81
L
V
S
R
A
P
Q
T
F
K
M
D
D
L
L
Site 5
T132
A
G
D
A
V
D
V
T
Q
D
Y
N
E
T
D
Site 6
Y135
A
V
D
V
T
Q
D
Y
N
E
T
D
W
S
Q
Site 7
S153
S
E
V
T
D
P
L
S
V
S
P
A
R
W
A
Site 8
S155
V
T
D
P
L
S
V
S
P
A
R
W
A
E
E
Site 9
Y163
P
A
R
W
A
E
E
Y
L
E
Q
S
E
E
K
Site 10
S167
A
E
E
Y
L
E
Q
S
E
E
K
L
W
L
G
Site 11
T181
G
E
P
E
G
T
A
T
D
R
W
Y
D
E
Y
Site 12
Y185
G
T
A
T
D
R
W
Y
D
E
Y
H
P
E
E
Site 13
Y188
T
D
R
W
Y
D
E
Y
H
P
E
E
D
L
Q
Site 14
S199
E
D
L
Q
H
T
A
S
D
F
V
A
K
V
D
Site 15
S228
Q
I
G
E
G
Q
V
S
L
E
S
G
A
G
S
Site 16
S231
E
G
Q
V
S
L
E
S
G
A
G
S
G
R
A
Site 17
S235
S
L
E
S
G
A
G
S
G
R
A
Q
A
E
Q
Site 18
T262
D
A
W
V
D
Q
F
T
R
P
V
N
T
S
A
Site 19
S268
F
T
R
P
V
N
T
S
A
L
D
M
E
F
E
Site 20
S279
M
E
F
E
R
A
K
S
A
I
E
S
D
V
D
Site 21
S283
R
A
K
S
A
I
E
S
D
V
D
F
W
D
K
Site 22
S310
A
E
A
H
P
W
L
S
D
Y
D
D
L
T
S
Site 23
Y312
A
H
P
W
L
S
D
Y
D
D
L
T
S
A
T
Site 24
T316
L
S
D
Y
D
D
L
T
S
A
T
Y
D
K
G
Site 25
S317
S
D
Y
D
D
L
T
S
A
T
Y
D
K
G
Y
Site 26
Y324
S
A
T
Y
D
K
G
Y
Q
F
E
E
E
N
P
Site 27
Y374
K
H
M
E
A
W
Q
Y
L
G
T
T
Q
A
E
Site 28
T425
L
Q
R
Q
A
C
E
T
L
R
D
W
L
R
Y
Site 29
Y432
T
L
R
D
W
L
R
Y
T
P
A
Y
A
H
L
Site 30
T433
L
R
D
W
L
R
Y
T
P
A
Y
A
H
L
V
Site 31
T441
P
A
Y
A
H
L
V
T
P
A
E
E
G
A
G
Site 32
S485
A
V
R
L
D
P
T
S
I
D
P
D
V
Q
C
Site 33
S516
D
C
F
T
A
A
L
S
V
R
P
N
D
Y
L
Site 34
Y522
L
S
V
R
P
N
D
Y
L
L
W
N
K
L
G
Site 35
S538
T
L
A
N
G
N
Q
S
E
E
A
V
A
A
Y
Site 36
Y555
A
L
E
L
Q
P
G
Y
I
R
S
R
Y
N
L
Site 37
S558
L
Q
P
G
Y
I
R
S
R
Y
N
L
G
I
S
Site 38
Y560
P
G
Y
I
R
S
R
Y
N
L
G
I
S
C
I
Site 39
S589
A
L
N
M
Q
R
K
S
R
G
P
R
G
E
G
Site 40
S600
R
G
E
G
G
A
M
S
E
N
I
W
S
T
L
Site 41
Y620
M
L
G
Q
S
D
A
Y
G
A
A
D
A
R
D
Site 42
T630
A
D
A
R
D
L
S
T
L
L
T
M
F
G
L
Site 43
T633
R
D
L
S
T
L
L
T
M
F
G
L
P
Q
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation