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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ERF
Full Name:
ETS domain-containing transcription factor ERF
Alias:
Ets2 repressor factor; ETS-domain transcription factor ERF; PE2; PE-2
Type:
Transcription protein
Mass (Da):
58703
Number AA:
548
UniProt ID:
P50548
International Prot ID:
IPI00032936
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003706
GO:0043565
GO:0003714
PhosphoSite+
KinaseNET
Biological Process:
GO:0008283
GO:0006357
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T3
_
_
_
_
_
M
K
T
P
A
D
T
G
F
A
Site 2
T7
_
M
K
T
P
A
D
T
G
F
A
F
P
D
W
Site 3
Y16
F
A
F
P
D
W
A
Y
K
P
E
S
S
P
G
Site 4
S20
D
W
A
Y
K
P
E
S
S
P
G
S
R
Q
I
Site 5
S21
W
A
Y
K
P
E
S
S
P
G
S
R
Q
I
Q
Site 6
S24
K
P
E
S
S
P
G
S
R
Q
I
Q
L
W
H
Site 7
Y42
E
L
L
R
K
E
E
Y
Q
G
V
I
A
W
Q
Site 8
Y52
V
I
A
W
Q
G
D
Y
G
E
F
V
I
K
D
Site 9
Y78
K
C
K
P
Q
M
N
Y
D
K
L
S
R
A
L
Site 10
Y88
L
S
R
A
L
R
Y
Y
Y
N
K
R
I
L
H
Site 11
Y89
S
R
A
L
R
Y
Y
Y
N
K
R
I
L
H
K
Site 12
T97
N
K
R
I
L
H
K
T
K
G
K
R
F
T
Y
Site 13
T103
K
T
K
G
K
R
F
T
Y
K
F
N
F
N
K
Site 14
Y104
T
K
G
K
R
F
T
Y
K
F
N
F
N
K
L
Site 15
S131
A
G
G
A
V
P
Q
S
A
P
P
V
P
S
G
Site 16
S137
Q
S
A
P
P
V
P
S
G
G
S
H
F
R
F
Site 17
S140
P
P
V
P
S
G
G
S
H
F
R
F
P
P
S
Site 18
S147
S
H
F
R
F
P
P
S
T
P
S
E
V
L
S
Site 19
T148
H
F
R
F
P
P
S
T
P
S
E
V
L
S
P
Site 20
S150
R
F
P
P
S
T
P
S
E
V
L
S
P
T
E
Site 21
S154
S
T
P
S
E
V
L
S
P
T
E
D
P
R
S
Site 22
T156
P
S
E
V
L
S
P
T
E
D
P
R
S
P
P
Site 23
S161
S
P
T
E
D
P
R
S
P
P
A
C
S
S
S
Site 24
S166
P
R
S
P
P
A
C
S
S
S
S
S
S
L
F
Site 25
S167
R
S
P
P
A
C
S
S
S
S
S
S
L
F
S
Site 26
S168
S
P
P
A
C
S
S
S
S
S
S
L
F
S
A
Site 27
S171
A
C
S
S
S
S
S
S
L
F
S
A
V
V
A
Site 28
S185
A
R
R
L
G
R
G
S
V
S
D
C
S
D
G
Site 29
S187
R
L
G
R
G
S
V
S
D
C
S
D
G
T
S
Site 30
S190
R
G
S
V
S
D
C
S
D
G
T
S
E
L
E
Site 31
S194
S
D
C
S
D
G
T
S
E
L
E
E
P
L
G
Site 32
Y235
D
P
G
V
F
R
V
Y
P
R
P
R
G
G
P
Site 33
S246
R
G
G
P
E
P
L
S
P
F
P
V
S
P
L
Site 34
S251
P
L
S
P
F
P
V
S
P
L
A
G
P
G
S
Site 35
T278
T
P
T
H
L
A
Y
T
P
S
P
T
L
S
P
Site 36
S280
T
H
L
A
Y
T
P
S
P
T
L
S
P
M
Y
Site 37
T282
L
A
Y
T
P
S
P
T
L
S
P
M
Y
P
S
Site 38
S284
Y
T
P
S
P
T
L
S
P
M
Y
P
S
G
G
Site 39
Y287
S
P
T
L
S
P
M
Y
P
S
G
G
G
G
P
Site 40
S289
T
L
S
P
M
Y
P
S
G
G
G
G
P
S
G
Site 41
S295
P
S
G
G
G
G
P
S
G
S
G
G
G
S
H
Site 42
S297
G
G
G
G
P
S
G
S
G
G
G
S
H
F
S
Site 43
S301
P
S
G
S
G
G
G
S
H
F
S
F
S
P
E
Site 44
S304
S
G
G
G
S
H
F
S
F
S
P
E
D
M
K
Site 45
S306
G
G
S
H
F
S
F
S
P
E
D
M
K
R
Y
Site 46
Y313
S
P
E
D
M
K
R
Y
L
Q
A
H
T
Q
S
Site 47
T318
K
R
Y
L
Q
A
H
T
Q
S
V
Y
N
Y
H
Site 48
Y322
Q
A
H
T
Q
S
V
Y
N
Y
H
L
S
P
R
Site 49
Y324
H
T
Q
S
V
Y
N
Y
H
L
S
P
R
A
F
Site 50
S327
S
V
Y
N
Y
H
L
S
P
R
A
F
L
H
Y
Site 51
T357
L
P
P
M
A
P
E
T
P
P
V
P
S
S
A
Site 52
S362
P
E
T
P
P
V
P
S
S
A
S
S
S
S
S
Site 53
S363
E
T
P
P
V
P
S
S
A
S
S
S
S
S
S
Site 54
S365
P
P
V
P
S
S
A
S
S
S
S
S
S
S
S
Site 55
S366
P
V
P
S
S
A
S
S
S
S
S
S
S
S
S
Site 56
S367
V
P
S
S
A
S
S
S
S
S
S
S
S
S
P
Site 57
S368
P
S
S
A
S
S
S
S
S
S
S
S
S
P
F
Site 58
S369
S
S
A
S
S
S
S
S
S
S
S
S
P
F
K
Site 59
S370
S
A
S
S
S
S
S
S
S
S
S
P
F
K
F
Site 60
S371
A
S
S
S
S
S
S
S
S
S
P
F
K
F
K
Site 61
S372
S
S
S
S
S
S
S
S
S
P
F
K
F
K
L
Site 62
S373
S
S
S
S
S
S
S
S
P
F
K
F
K
L
Q
Site 63
S431
Q
I
K
V
E
P
I
S
E
G
E
S
E
E
V
Site 64
S435
E
P
I
S
E
G
E
S
E
E
V
E
V
T
D
Site 65
T441
E
S
E
E
V
E
V
T
D
I
S
D
E
D
E
Site 66
S444
E
V
E
V
T
D
I
S
D
E
D
E
E
D
G
Site 67
T456
E
D
G
E
V
F
K
T
P
R
A
P
P
A
P
Site 68
S475
P
G
E
A
P
G
A
S
Q
C
M
P
L
K
L
Site 69
S489
L
R
F
K
R
R
W
S
E
D
C
R
L
E
G
Site 70
T526
G
E
A
G
G
P
L
T
P
R
R
V
S
S
D
Site 71
S531
P
L
T
P
R
R
V
S
S
D
L
Q
H
A
T
Site 72
S532
L
T
P
R
R
V
S
S
D
L
Q
H
A
T
A
Site 73
T538
S
S
D
L
Q
H
A
T
A
Q
L
S
L
E
H
Site 74
S542
Q
H
A
T
A
Q
L
S
L
E
H
R
D
S
_
Site 75
S548
L
S
L
E
H
R
D
S
_
_
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation