KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
CCT8
Full Name:
T-complex protein 1 subunit theta
Alias:
C21orf112; CCTQ; Chaperonin containing TCP1, subunit 8 (theta); KIAA0002; NY-REN-15; PRED71; TCPQ
Type:
Chaperone protein
Mass (Da):
59621
Number AA:
548
UniProt ID:
P50990
International Prot ID:
IPI00784090
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005829
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0042623
GO:0051082
PhosphoSite+
KinaseNET
Biological Process:
GO:0006457
GO:0000074
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S23
K
E
G
A
K
H
F
S
G
L
E
E
A
V
Y
Site 2
Y30
S
G
L
E
E
A
V
Y
R
N
I
Q
A
C
K
Site 3
T42
A
C
K
E
L
A
Q
T
T
R
T
A
Y
G
P
Site 4
T45
E
L
A
Q
T
T
R
T
A
Y
G
P
N
G
M
Site 5
Y47
A
Q
T
T
R
T
A
Y
G
P
N
G
M
N
K
Site 6
S162
R
D
I
D
E
V
S
S
L
L
R
T
S
I
M
Site 7
T166
E
V
S
S
L
L
R
T
S
I
M
S
K
Q
Y
Site 8
S167
V
S
S
L
L
R
T
S
I
M
S
K
Q
Y
G
Site 9
S170
L
L
R
T
S
I
M
S
K
Q
Y
G
N
E
V
Site 10
Y173
T
S
I
M
S
K
Q
Y
G
N
E
V
F
L
A
Site 11
T227
G
M
V
F
K
K
E
T
E
G
D
V
T
S
V
Site 12
T232
K
E
T
E
G
D
V
T
S
V
K
D
A
K
I
Site 13
S233
E
T
E
G
D
V
T
S
V
K
D
A
K
I
A
Site 14
Y242
K
D
A
K
I
A
V
Y
S
C
P
F
D
G
M
Site 15
T261
K
G
T
V
L
I
K
T
A
E
E
L
M
N
F
Site 16
S269
A
E
E
L
M
N
F
S
K
G
E
E
N
L
M
Site 17
S317
I
M
L
V
R
L
N
S
K
W
D
L
R
R
L
Site 18
S349
E
E
M
G
H
C
D
S
V
Y
L
S
E
V
G
Site 19
Y351
M
G
H
C
D
S
V
Y
L
S
E
V
G
D
T
Site 20
S353
H
C
D
S
V
Y
L
S
E
V
G
D
T
Q
V
Site 21
S380
S
T
I
V
L
R
G
S
T
D
N
L
M
D
D
Site 22
T381
T
I
V
L
R
G
S
T
D
N
L
M
D
D
I
Site 23
T398
A
V
D
D
G
V
N
T
F
K
V
L
T
R
D
Site 24
T415
L
V
P
G
G
G
A
T
E
I
E
L
A
K
Q
Site 25
Y426
L
A
K
Q
I
T
S
Y
G
E
T
C
P
G
L
Site 26
T429
Q
I
T
S
Y
G
E
T
C
P
G
L
E
Q
Y
Site 27
Y436
T
C
P
G
L
E
Q
Y
A
I
K
K
F
A
E
Site 28
Y468
N
E
V
I
S
K
L
Y
A
V
H
Q
E
G
N
Site 29
Y505
L
D
T
Y
L
G
K
Y
W
A
I
K
L
A
T
Site 30
T512
Y
W
A
I
K
L
A
T
N
A
A
V
T
V
L
Site 31
S537
A
G
G
P
K
P
P
S
G
K
K
D
W
D
D
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation