PhosphoNET

           
Protein Info 
   
Short Name:  GZMM
Full Name:  Granzyme M
Alias:  Met-1 serine protease;Met-ase;Natural killer cell granular protease
Type: 
Mass (Da):  27545
Number AA:  257
UniProt ID:  P51124
International Prot ID: 
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:      Uniprot OncoNet
Molecular Function:      PhosphoSite+ KinaseNET
Biological Process:      Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1T24SVGSSFGTQIIGGRE
Site 2S36GREVIPHSRPYMASL
Site 3Y39VIPHSRPYMASLQRN
Site 4S42HSRPYMASLQRNGSH
Site 5T83RLVLGLHTLDSPGLT
Site 6Y102AAIQHPRYKPVPALE
Site 7T126GKVKPSRTIRPLALP
Site 8S160THQGGRLSRVLRELD
Site 9T173LDLQVLDTRMCNNSR
Site 10S185NSRFWNGSLSPSMVC
Site 11S207QAPCKGDSGGPLVCG
Site 12S224RVLAGVLSFSSRVCT
Site 13S226LAGVLSFSSRVCTDI
Site 14T231SFSSRVCTDIFKPPV
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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