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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ENaC beta
Full Name:
Amiloride-sensitive sodium channel subunit beta
Alias:
Beta-NaCH;Epithelial Na(+) channel subunit beta;Nonvoltage-gated sodium channel 1 subunit beta;SCNEB
Type:
Channel protein
Mass (Da):
72659
Number AA:
640
UniProt ID:
P51168
International Prot ID:
IPI00178024
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0050699
GO:0015280
GO:0031402
PhosphoSite+
KinaseNET
Biological Process:
GO:0007588
GO:0050909
GO:0006814
Phosida
TranscriptoNet
STRING
Kinexus Products
Amiloride-sensitive sodium channel subunit beta pan-specific antibody AB-NN317-1#http://www.kinexusproducts.ca/ProductInfo_Antibody.aspx?Product_Number=AB-NN317-1#Amiloride sensitive sodium channel subunit beta pan-specific antibody AB-NN317-2#http://www.kinexusproducts.ca/ProductInfo_Antibody.aspx?Product_Number=AB-NN317-2
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y20
R
L
Q
K
G
P
G
Y
T
Y
K
E
L
L
V
Site 2
S561
K
L
V
A
L
A
K
S
L
R
Q
R
R
A
Q
Site 3
S570
R
Q
R
R
A
Q
A
S
Y
A
G
P
P
P
T
Site 4
Y571
Q
R
R
A
Q
A
S
Y
A
G
P
P
P
T
V
Site 5
T586
A
E
L
V
E
A
H
T
N
F
G
F
Q
P
D
Site 6
T594
N
F
G
F
Q
P
D
T
A
P
R
S
P
N
T
Site 7
S598
Q
P
D
T
A
P
R
S
P
N
T
G
P
Y
P
Site 8
T601
T
A
P
R
S
P
N
T
G
P
Y
P
S
E
Q
Site 9
Y604
R
S
P
N
T
G
P
Y
P
S
E
Q
A
L
P
Site 10
S606
P
N
T
G
P
Y
P
S
E
Q
A
L
P
I
P
Site 11
T615
Q
A
L
P
I
P
G
T
P
P
P
N
Y
D
S
Site 12
Y620
P
G
T
P
P
P
N
Y
D
S
L
R
L
Q
P
Site 13
S622
T
P
P
P
N
Y
D
S
L
R
L
Q
P
L
D
Site 14
S633
Q
P
L
D
V
I
E
S
D
S
E
G
D
A
I
Site 15
S635
L
D
V
I
E
S
D
S
E
G
D
A
I
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation