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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
RORC
Full Name:
Nuclear receptor ROR-gamma
Alias:
Nuclear receptor RZR-gamma;Nuclear receptor subfamily 1 group F member 3;Retinoid-related orphan receptor-gamma
Type:
Mass (Da):
58195
Number AA:
518
UniProt ID:
P51449
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S12
P
Q
R
Q
H
R
A
S
R
E
L
L
A
A
K
Site 2
S24
A
A
K
K
T
H
T
S
Q
I
E
V
I
P
C
Site 3
Y43
D
K
S
S
G
I
H
Y
G
V
I
T
C
E
G
Site 4
Y65
S
Q
R
C
N
A
A
Y
S
C
T
R
Q
Q
N
Site 5
S107
A
V
K
F
G
R
M
S
K
K
Q
R
D
S
L
Site 6
S113
M
S
K
K
Q
R
D
S
L
H
A
E
V
Q
K
Site 7
T136
Q
Q
E
P
V
V
K
T
P
P
A
G
A
Q
G
Site 8
T148
A
Q
G
A
D
T
L
T
Y
T
L
G
L
P
D
Site 9
Y149
Q
G
A
D
T
L
T
Y
T
L
G
L
P
D
G
Site 10
S162
D
G
Q
L
P
L
G
S
S
P
D
L
P
E
A
Site 11
S163
G
Q
L
P
L
G
S
S
P
D
L
P
E
A
S
Site 12
S170
S
P
D
L
P
E
A
S
A
C
P
P
G
L
L
Site 13
S180
P
P
G
L
L
K
A
S
G
S
G
P
S
Y
S
Site 14
S182
G
L
L
K
A
S
G
S
G
P
S
Y
S
N
N
Site 15
S185
K
A
S
G
S
G
P
S
Y
S
N
N
L
A
K
Site 16
Y186
A
S
G
S
G
P
S
Y
S
N
N
L
A
K
A
Site 17
S187
S
G
S
G
P
S
Y
S
N
N
L
A
K
A
G
Site 18
S205
A
S
C
H
L
E
Y
S
P
E
R
G
K
A
E
Site 19
S216
G
K
A
E
G
R
E
S
F
Y
S
T
G
S
Q
Site 20
Y218
A
E
G
R
E
S
F
Y
S
T
G
S
Q
L
T
Site 21
S219
E
G
R
E
S
F
Y
S
T
G
S
Q
L
T
P
Site 22
T220
G
R
E
S
F
Y
S
T
G
S
Q
L
T
P
D
Site 23
S222
E
S
F
Y
S
T
G
S
Q
L
T
P
D
R
C
Site 24
T225
Y
S
T
G
S
Q
L
T
P
D
R
C
G
L
R
Site 25
S250
E
L
G
Q
G
P
D
S
Y
G
S
P
S
F
R
Site 26
Y251
L
G
Q
G
P
D
S
Y
G
S
P
S
F
R
S
Site 27
S253
Q
G
P
D
S
Y
G
S
P
S
F
R
S
T
P
Site 28
S255
P
D
S
Y
G
S
P
S
F
R
S
T
P
E
A
Site 29
S258
Y
G
S
P
S
F
R
S
T
P
E
A
P
Y
A
Site 30
T259
G
S
P
S
F
R
S
T
P
E
A
P
Y
A
S
Site 31
Y264
R
S
T
P
E
A
P
Y
A
S
L
T
E
I
E
Site 32
S266
T
P
E
A
P
Y
A
S
L
T
E
I
E
H
L
Site 33
T268
E
A
P
Y
A
S
L
T
E
I
E
H
L
V
Q
Site 34
S276
E
I
E
H
L
V
Q
S
V
C
K
S
Y
R
E
Site 35
S280
L
V
Q
S
V
C
K
S
Y
R
E
T
C
Q
L
Site 36
T284
V
C
K
S
Y
R
E
T
C
Q
L
R
L
E
D
Site 37
S297
E
D
L
L
R
Q
R
S
N
I
F
S
R
E
E
Site 38
S301
R
Q
R
S
N
I
F
S
R
E
E
V
T
G
Y
Site 39
Y308
S
R
E
E
V
T
G
Y
Q
R
K
S
M
W
E
Site 40
Y330
H
L
T
E
A
I
Q
Y
V
V
E
F
A
K
R
Site 41
S339
V
E
F
A
K
R
L
S
G
F
M
E
L
C
Q
Site 42
Y369
L
V
R
M
C
R
A
Y
N
A
D
N
R
T
V
Site 43
T375
A
Y
N
A
D
N
R
T
V
F
F
E
G
K
Y
Site 44
Y382
T
V
F
F
E
G
K
Y
G
G
M
E
L
F
R
Site 45
S408
F
D
F
S
H
S
L
S
A
L
H
F
S
E
D
Site 46
Y444
R
K
V
E
Q
L
Q
Y
N
L
E
L
A
F
H
Site 47
S461
L
C
K
T
H
R
Q
S
I
L
A
K
L
P
P
Site 48
S474
P
P
K
G
K
L
R
S
L
C
S
Q
H
V
E
Site 49
S477
G
K
L
R
S
L
C
S
Q
H
V
E
R
L
Q
Site 50
Y502
Q
A
A
F
P
P
L
Y
K
E
L
F
S
T
E
Site 51
S507
P
L
Y
K
E
L
F
S
T
E
T
E
S
P
V
Site 52
T508
L
Y
K
E
L
F
S
T
E
T
E
S
P
V
G
Site 53
T510
K
E
L
F
S
T
E
T
E
S
P
V
G
L
S
Site 54
S512
L
F
S
T
E
T
E
S
P
V
G
L
S
K
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation