PhosphoNET

           
Protein Info 
   
Short Name:  MMP16
Full Name:  Matrix metalloproteinase-16
Alias:  C8orf57; DKFZp761D112; Matrix metallopeptidase 16 (membrane-inserted); Matrix metalloproteinase-16; Membrane-type matrix metalloproteinase 3; Membrane-type-3 matrix metalloproteinase; MMP-16; MMPX2; MMP-X2; MT3MMP; MT3-MMP; MT-MMP 3; MT-MMP2; MTMMP3; MT-MMP3
Type:  EC 3.4.24.-; Protease
Mass (Da):  69521
Number AA:  607
UniProt ID:  P51512
International Prot ID:  IPI00019243
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0009986  GO:0005887  GO:0005578 Uniprot OncoNet
Molecular Function:  GO:0005509  GO:0008047  GO:0004222 PhosphoSite+ KinaseNET
Biological Process:  GO:0030574  GO:0006508   Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1T5___MILLTFSTGRRL
Site 2T8MILLTFSTGRRLDFV
Site 3Y50VEVWLQKYGYLPPTD
Site 4Y52VWLQKYGYLPPTDPR
Site 5T56KYGYLPPTDPRMSVL
Site 6S61PPTDPRMSVLRSAET
Site 7S65PRMSVLRSAETMQSA
Site 8S71RSAETMQSALAAMQQ
Site 9T92TGKVDRNTIDWMKKP
Site 10T107RCGVPDQTRGSSKFH
Site 11S110VPDQTRGSSKFHIRR
Site 12S111PDQTRGSSKFHIRRK
Site 13Y134WQHKHITYSIKNVTP
Site 14Y377NNRVMDGYPMQITYF
Site 15T382DGYPMQITYFWRGLP
Site 16T478PGYPKPITVWKGIPE
Site 17Y521ILKVEPGYPRSILKD
Site 18T592FQFKRKGTPRHILYC
Site 19Y598GTPRHILYCKRSMQE
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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