KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
ZNF84
Full Name:
Zinc finger protein 84
Alias:
HPF2; Zinc finger 84; Zinc finger HPF2
Type:
Intracellular protein
Mass (Da):
85457
Number AA:
738
UniProt ID:
P51523
International Prot ID:
IPI00333480
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003677
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0006355
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S7
_
M
T
M
L
Q
E
S
F
S
F
D
D
L
S
Site 2
S9
T
M
L
Q
E
S
F
S
F
D
D
L
S
V
D
Site 3
S14
S
F
S
F
D
D
L
S
V
D
F
T
Q
K
E
Site 4
T18
D
D
L
S
V
D
F
T
Q
K
E
W
Q
L
L
Site 5
S28
E
W
Q
L
L
D
P
S
Q
K
N
L
Y
K
D
Site 6
Y33
D
P
S
Q
K
N
L
Y
K
D
V
M
L
E
N
Site 7
S46
E
N
Y
S
S
L
V
S
L
G
Y
E
V
M
K
Site 8
S75
V
G
D
G
E
I
P
S
S
D
S
P
E
V
W
Site 9
S76
G
D
G
E
I
P
S
S
D
S
P
E
V
W
K
Site 10
S78
G
E
I
P
S
S
D
S
P
E
V
W
K
V
D
Site 11
S126
N
F
V
P
L
R
K
S
N
S
E
G
D
L
D
Site 12
S128
V
P
L
R
K
S
N
S
E
G
D
L
D
G
L
Site 13
Y150
L
L
I
P
K
G
D
Y
G
K
A
E
S
D
D
Site 14
S155
G
D
Y
G
K
A
E
S
D
D
F
N
V
F
D
Site 15
T173
L
H
S
K
P
E
D
T
D
T
W
L
K
Y
Y
Site 16
T175
S
K
P
E
D
T
D
T
W
L
K
Y
Y
D
C
Site 17
Y179
D
T
D
T
W
L
K
Y
Y
D
C
D
K
Y
K
Site 18
Y180
T
D
T
W
L
K
Y
Y
D
C
D
K
Y
K
E
Site 19
Y185
K
Y
Y
D
C
D
K
Y
K
E
S
Y
K
K
S
Site 20
Y197
K
K
S
Q
I
I
I
Y
H
R
N
R
L
G
E
Site 21
Y207
N
R
L
G
E
K
L
Y
E
C
S
E
C
R
K
Site 22
S210
G
E
K
L
Y
E
C
S
E
C
R
K
R
F
S
Site 23
S217
S
E
C
R
K
R
F
S
K
K
P
S
L
I
K
Site 24
S221
K
R
F
S
K
K
P
S
L
I
K
H
Q
S
R
Site 25
S227
P
S
L
I
K
H
Q
S
R
H
I
R
D
I
A
Site 26
S248
G
K
T
F
P
Q
K
S
Q
F
I
T
H
H
R
Site 27
T252
P
Q
K
S
Q
F
I
T
H
H
R
T
H
T
G
Site 28
T256
Q
F
I
T
H
H
R
T
H
T
G
E
K
P
Y
Site 29
T258
I
T
H
H
R
T
H
T
G
E
K
P
Y
N
C
Site 30
Y263
T
H
T
G
E
K
P
Y
N
C
S
Q
C
G
K
Site 31
S266
G
E
K
P
Y
N
C
S
Q
C
G
K
A
F
S
Site 32
S273
S
Q
C
G
K
A
F
S
Q
K
S
Q
L
T
S
Site 33
S276
G
K
A
F
S
Q
K
S
Q
L
T
S
H
Q
R
Site 34
S280
S
Q
K
S
Q
L
T
S
H
Q
R
T
H
T
G
Site 35
T284
Q
L
T
S
H
Q
R
T
H
T
G
E
K
P
Y
Site 36
T286
T
S
H
Q
R
T
H
T
G
E
K
P
Y
E
C
Site 37
Y291
T
H
T
G
E
K
P
Y
E
C
G
E
C
G
K
Site 38
S301
G
E
C
G
K
A
F
S
R
K
S
H
L
I
S
Site 39
S304
G
K
A
F
S
R
K
S
H
L
I
S
H
W
R
Site 40
S308
S
R
K
S
H
L
I
S
H
W
R
T
H
T
G
Site 41
T312
H
L
I
S
H
W
R
T
H
T
G
E
K
P
Y
Site 42
T314
I
S
H
W
R
T
H
T
G
E
K
P
Y
G
C
Site 43
Y319
T
H
T
G
E
K
P
Y
G
C
N
E
C
G
R
Site 44
S329
N
E
C
G
R
A
F
S
E
K
S
N
L
I
N
Site 45
S332
G
R
A
F
S
E
K
S
N
L
I
N
H
Q
R
Site 46
T342
I
N
H
Q
R
I
H
T
G
E
K
P
F
E
C
Site 47
S357
R
E
C
G
K
A
F
S
R
K
S
Q
L
V
T
Site 48
S360
G
K
A
F
S
R
K
S
Q
L
V
T
H
H
R
Site 49
T364
S
R
K
S
Q
L
V
T
H
H
R
T
H
T
G
Site 50
T370
V
T
H
H
R
T
H
T
G
T
K
P
F
G
C
Site 51
T372
H
H
R
T
H
T
G
T
K
P
F
G
C
S
D
Site 52
S388
R
K
A
F
F
E
K
S
E
L
I
R
H
Q
T
Site 53
T395
S
E
L
I
R
H
Q
T
I
H
T
G
E
K
P
Site 54
T398
I
R
H
Q
T
I
H
T
G
E
K
P
Y
E
C
Site 55
Y403
I
H
T
G
E
K
P
Y
E
C
S
E
C
R
K
Site 56
S406
G
E
K
P
Y
E
C
S
E
C
R
K
A
F
R
Site 57
S416
R
K
A
F
R
E
R
S
S
L
I
N
H
Q
R
Site 58
S417
K
A
F
R
E
R
S
S
L
I
N
H
Q
R
T
Site 59
T424
S
L
I
N
H
Q
R
T
H
T
G
E
K
P
H
Site 60
T426
I
N
H
Q
R
T
H
T
G
E
K
P
H
G
C
Site 61
S441
I
Q
C
G
K
A
F
S
Q
K
S
H
L
I
S
Site 62
S444
G
K
A
F
S
Q
K
S
H
L
I
S
H
Q
M
Site 63
S448
S
Q
K
S
H
L
I
S
H
Q
M
T
H
T
G
Site 64
T452
H
L
I
S
H
Q
M
T
H
T
G
E
K
P
F
Site 65
S462
G
E
K
P
F
I
C
S
K
C
G
K
A
F
S
Site 66
S469
S
K
C
G
K
A
F
S
R
K
S
Q
L
V
R
Site 67
S472
G
K
A
F
S
R
K
S
Q
L
V
R
H
Q
R
Site 68
T480
Q
L
V
R
H
Q
R
T
H
T
G
E
K
P
Y
Site 69
T482
V
R
H
Q
R
T
H
T
G
E
K
P
Y
E
C
Site 70
Y487
T
H
T
G
E
K
P
Y
E
C
S
E
C
G
K
Site 71
S490
G
E
K
P
Y
E
C
S
E
C
G
K
A
F
S
Site 72
S497
S
E
C
G
K
A
F
S
E
K
L
S
L
T
N
Site 73
S501
K
A
F
S
E
K
L
S
L
T
N
H
Q
R
I
Site 74
T503
F
S
E
K
L
S
L
T
N
H
Q
R
I
H
T
Site 75
T510
T
N
H
Q
R
I
H
T
G
E
K
P
Y
V
C
Site 76
Y515
I
H
T
G
E
K
P
Y
V
C
S
E
C
G
K
Site 77
T536
H
L
I
S
H
Q
R
T
H
T
G
E
K
P
Y
Site 78
T538
I
S
H
Q
R
T
H
T
G
E
K
P
Y
E
C
Site 79
S546
G
E
K
P
Y
E
C
S
E
C
G
K
A
F
G
Site 80
S556
G
K
A
F
G
E
K
S
S
L
A
T
H
Q
R
Site 81
S557
K
A
F
G
E
K
S
S
L
A
T
H
Q
R
T
Site 82
T560
G
E
K
S
S
L
A
T
H
Q
R
T
H
T
G
Site 83
T564
S
L
A
T
H
Q
R
T
H
T
G
E
K
P
Y
Site 84
T566
A
T
H
Q
R
T
H
T
G
E
K
P
Y
E
C
Site 85
Y571
T
H
T
G
E
K
P
Y
E
C
R
D
C
E
K
Site 86
S581
R
D
C
E
K
A
F
S
Q
K
S
Q
L
N
T
Site 87
S584
E
K
A
F
S
Q
K
S
Q
L
N
T
H
Q
R
Site 88
T588
S
Q
K
S
Q
L
N
T
H
Q
R
I
H
T
G
Site 89
T594
N
T
H
Q
R
I
H
T
G
E
K
P
Y
E
C
Site 90
S612
R
K
A
F
F
E
K
S
E
L
I
R
H
L
R
Site 91
T620
E
L
I
R
H
L
R
T
H
T
G
E
K
P
Y
Site 92
T622
I
R
H
L
R
T
H
T
G
E
K
P
Y
E
C
Site 93
Y627
T
H
T
G
E
K
P
Y
E
C
N
E
C
R
K
Site 94
S640
R
K
A
F
R
E
K
S
S
L
I
N
H
Q
R
Site 95
S658
G
E
K
P
F
E
C
S
E
C
G
K
A
F
S
Site 96
S665
S
E
C
G
K
A
F
S
R
K
S
H
L
I
P
Site 97
S668
G
K
A
F
S
R
K
S
H
L
I
P
H
Q
R
Site 98
T676
H
L
I
P
H
Q
R
T
H
T
G
E
K
P
Y
Site 99
T678
I
P
H
Q
R
T
H
T
G
E
K
P
Y
G
C
Site 100
S686
G
E
K
P
Y
G
C
S
E
C
R
K
A
F
S
Site 101
S693
S
E
C
R
K
A
F
S
Q
K
S
Q
L
V
N
Site 102
S696
R
K
A
F
S
Q
K
S
Q
L
V
N
H
Q
R
Site 103
T706
V
N
H
Q
R
I
H
T
G
E
K
P
Y
R
C
Site 104
Y711
I
H
T
G
E
K
P
Y
R
C
I
E
C
G
K
Site 105
S721
I
E
C
G
K
A
F
S
Q
K
S
Q
L
I
N
Site 106
S724
G
K
A
F
S
Q
K
S
Q
L
I
N
H
Q
R
Site 107
T734
I
N
H
Q
R
T
H
T
V
K
K
S
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation