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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ARSE
Full Name:
Arylsulfatase E
Alias:
Type:
Mass (Da):
65669
Number AA:
589
UniProt ID:
P51690
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S30
L
S
L
A
P
S
A
S
S
D
I
S
A
S
R
Site 2
S31
S
L
A
P
S
A
S
S
D
I
S
A
S
R
P
Site 3
S34
P
S
A
S
S
D
I
S
A
S
R
P
N
I
L
Site 4
Y56
G
I
G
D
I
G
C
Y
G
N
N
T
M
R
T
Site 5
T63
Y
G
N
N
T
M
R
T
P
N
I
D
R
L
A
Site 6
T77
A
E
D
G
V
K
L
T
Q
H
I
S
A
A
S
Site 7
S81
V
K
L
T
Q
H
I
S
A
A
S
L
C
T
P
Site 8
S84
T
Q
H
I
S
A
A
S
L
C
T
P
S
R
A
Site 9
T95
P
S
R
A
A
F
L
T
G
R
Y
P
V
R
S
Site 10
S102
T
G
R
Y
P
V
R
S
G
M
V
S
S
I
G
Site 11
T116
G
Y
R
V
L
Q
W
T
G
A
S
G
G
L
P
Site 12
T127
G
G
L
P
T
N
E
T
T
F
A
K
I
L
K
Site 13
T128
G
L
P
T
N
E
T
T
F
A
K
I
L
K
E
Site 14
Y138
K
I
L
K
E
K
G
Y
A
T
G
L
I
G
K
Site 15
T260
C
F
L
M
R
N
H
T
I
T
E
Q
P
M
C
Site 16
S281
L
I
L
Q
E
V
A
S
F
L
K
R
N
K
H
Site 17
S314
M
E
N
F
L
G
K
S
L
H
G
L
Y
G
D
Site 18
Y319
G
K
S
L
H
G
L
Y
G
D
N
V
E
E
M
Site 19
Y349
L
S
N
S
T
L
I
Y
F
T
S
D
H
G
G
Site 20
S352
S
T
L
I
Y
F
T
S
D
H
G
G
S
L
E
Site 21
S357
F
T
S
D
H
G
G
S
L
E
N
Q
L
G
N
Site 22
Y367
N
Q
L
G
N
T
Q
Y
G
G
W
N
G
I
Y
Site 23
Y374
Y
G
G
W
N
G
I
Y
K
G
G
K
G
M
G
Site 24
S448
L
L
G
T
A
Q
H
S
D
H
E
F
L
M
H
Site 25
Y493
P
E
G
A
G
A
C
Y
G
R
K
V
C
P
C
Site 26
S517
P
P
L
L
F
D
L
S
R
D
P
S
E
T
H
Site 27
S521
F
D
L
S
R
D
P
S
E
T
H
I
L
T
P
Site 28
T523
L
S
R
D
P
S
E
T
H
I
L
T
P
A
S
Site 29
T527
P
S
E
T
H
I
L
T
P
A
S
E
P
V
F
Site 30
Y535
P
A
S
E
P
V
F
Y
Q
V
M
E
R
V
Q
Site 31
T551
A
V
W
E
H
Q
R
T
L
S
P
V
P
L
Q
Site 32
S553
W
E
H
Q
R
T
L
S
P
V
P
L
Q
L
D
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation