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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
GPR143
Full Name:
G-protein coupled receptor 143
Alias:
G protein-coupled receptor 143; GP143; OA1; Ocular albinism 1 (Nettleship-Falls); Ocular albinism type 1; Ocular albinism type 1 protein
Type:
Mass (Da):
43860
Number AA:
404
UniProt ID:
P51810
International Prot ID:
IPI00218565
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0016021
GO:0005624
Uniprot
OncoNet
Molecular Function:
GO:0004930
PhosphoSite+
KinaseNET
Biological Process:
GO:0007186
GO:0006726
GO:0007601
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T8
M
A
S
P
R
L
G
T
F
C
C
P
T
R
D
Site 2
S59
R
R
P
A
G
P
G
S
P
A
T
S
P
P
A
Site 3
T62
A
G
P
G
S
P
A
T
S
P
P
A
S
V
R
Site 4
S63
G
P
G
S
P
A
T
S
P
P
A
S
V
R
I
Site 5
S101
G
F
P
N
F
V
D
S
V
S
D
M
N
H
T
Site 6
S103
P
N
F
V
D
S
V
S
D
M
N
H
T
E
I
Site 7
Y157
G
L
S
T
I
L
L
Y
H
I
M
A
W
G
L
Site 8
Y177
V
E
G
A
A
M
L
Y
Y
P
S
V
S
R
C
Site 9
Y178
E
G
A
A
M
L
Y
Y
P
S
V
S
R
C
E
Site 10
S180
A
A
M
L
Y
Y
P
S
V
S
R
C
E
R
G
Site 11
S182
M
L
Y
Y
P
S
V
S
R
C
E
R
G
L
D
Site 12
T216
N
P
I
L
F
Q
K
T
V
T
A
V
A
S
L
Site 13
T218
I
L
F
Q
K
T
V
T
A
V
A
S
L
L
K
Site 14
S222
K
T
V
T
A
V
A
S
L
L
K
G
R
Q
G
Site 15
Y231
L
K
G
R
Q
G
I
Y
T
E
N
E
R
R
M
Site 16
T232
K
G
R
Q
G
I
Y
T
E
N
E
R
R
M
G
Site 17
T286
G
S
L
K
P
V
R
T
A
A
K
T
T
W
F
Site 18
S322
G
C
S
L
G
F
Q
S
P
R
K
E
I
Q
W
Site 19
S331
R
K
E
I
Q
W
E
S
L
T
T
S
A
A
E
Site 20
T334
I
Q
W
E
S
L
T
T
S
A
A
E
G
A
H
Site 21
S335
Q
W
E
S
L
T
T
S
A
A
E
G
A
H
P
Site 22
S343
A
A
E
G
A
H
P
S
P
L
M
P
H
E
N
Site 23
S353
M
P
H
E
N
P
A
S
G
K
V
S
Q
V
G
Site 24
S357
N
P
A
S
G
K
V
S
Q
V
G
G
Q
T
S
Site 25
S364
S
Q
V
G
G
Q
T
S
D
E
A
L
S
M
L
Site 26
S369
Q
T
S
D
E
A
L
S
M
L
S
E
G
S
D
Site 27
T379
S
E
G
S
D
A
S
T
I
E
I
H
T
A
S
Site 28
T384
A
S
T
I
E
I
H
T
A
S
E
S
C
N
K
Site 29
S386
T
I
E
I
H
T
A
S
E
S
C
N
K
N
E
Site 30
S388
E
I
H
T
A
S
E
S
C
N
K
N
E
G
D
Site 31
T400
E
G
D
P
A
L
P
T
H
G
D
L
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation