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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ADCY7
Full Name:
Adenylate cyclase type 7
Alias:
ATP pyrophosphate-lyase 7;Adenylate cyclase type VII;Adenylyl cyclase 7
Type:
Mass (Da):
120308
Number AA:
1080
UniProt ID:
P51828
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y7
_
M
P
A
K
G
R
Y
F
L
N
E
G
E
E
Site 2
Y22
G
P
D
Q
D
A
L
Y
E
K
Y
Q
L
T
S
Site 3
Y25
Q
D
A
L
Y
E
K
Y
Q
L
T
S
Q
H
G
Site 4
S29
Y
E
K
Y
Q
L
T
S
Q
H
G
P
L
L
L
Site 5
S60
A
F
S
Q
G
D
P
S
R
H
Q
A
I
L
G
Site 6
S154
A
V
A
V
G
A
V
S
T
A
S
H
L
L
V
Site 7
T155
V
A
V
G
A
V
S
T
A
S
H
L
L
V
L
Site 8
S157
V
G
A
V
S
T
A
S
H
L
L
V
L
G
S
Site 9
T210
D
A
S
R
D
L
F
T
Y
T
V
K
C
I
Q
Site 10
T212
S
R
D
L
F
T
Y
T
V
K
C
I
Q
I
R
Site 11
Y271
D
N
N
F
H
S
L
Y
V
K
R
H
Q
N
V
Site 12
S293
V
G
F
T
Q
L
A
S
D
C
S
P
K
E
L
Site 13
T365
I
K
Q
V
R
E
A
T
G
V
D
I
N
M
R
Site 14
Y392
I
G
L
R
K
W
Q
Y
D
V
W
S
H
D
V
Site 15
S400
D
V
W
S
H
D
V
S
L
A
N
R
M
E
A
Site 16
Y428
L
K
H
L
D
K
A
Y
E
V
E
D
G
H
G
Site 17
Y441
H
G
Q
Q
R
D
P
Y
L
K
E
M
N
I
R
Site 18
Y450
K
E
M
N
I
R
T
Y
L
V
I
D
P
R
S
Site 19
S457
Y
L
V
I
D
P
R
S
Q
Q
P
P
P
P
S
Site 20
S464
S
Q
Q
P
P
P
P
S
Q
H
L
P
R
P
K
Site 21
S481
A
A
L
K
M
R
A
S
V
R
M
T
R
Y
L
Site 22
T485
M
R
A
S
V
R
M
T
R
Y
L
E
S
W
G
Site 23
Y487
A
S
V
R
M
T
R
Y
L
E
S
W
G
A
A
Site 24
S505
A
H
L
N
H
R
E
S
V
S
S
G
E
T
H
Site 25
S508
N
H
R
E
S
V
S
S
G
E
T
H
V
P
N
Site 26
T511
E
S
V
S
S
G
E
T
H
V
P
N
G
R
R
Site 27
S521
P
N
G
R
R
P
K
S
V
P
Q
R
H
R
R
Site 28
T529
V
P
Q
R
H
R
R
T
P
D
R
S
M
S
P
Site 29
S533
H
R
R
T
P
D
R
S
M
S
P
K
G
R
S
Site 30
S535
R
T
P
D
R
S
M
S
P
K
G
R
S
E
D
Site 31
S540
S
M
S
P
K
G
R
S
E
D
D
S
Y
D
D
Site 32
S544
K
G
R
S
E
D
D
S
Y
D
D
E
M
L
S
Site 33
Y545
G
R
S
E
D
D
S
Y
D
D
E
M
L
S
A
Site 34
S551
S
Y
D
D
E
M
L
S
A
I
E
G
L
S
S
Site 35
S558
S
A
I
E
G
L
S
S
T
R
P
C
C
S
K
Site 36
S564
S
S
T
R
P
C
C
S
K
S
D
D
F
Y
T
Site 37
T571
S
K
S
D
D
F
Y
T
F
G
S
I
F
L
E
Site 38
Y585
E
K
G
F
E
R
E
Y
R
L
A
P
I
P
R
Site 39
T653
R
C
C
P
A
R
G
T
L
C
T
I
S
E
R
Site 40
T656
P
A
R
G
T
L
C
T
I
S
E
R
V
E
T
Site 41
S658
R
G
T
L
C
T
I
S
E
R
V
E
T
Q
P
Site 42
T663
T
I
S
E
R
V
E
T
Q
P
L
L
R
L
T
Site 43
T783
N
L
T
K
P
N
G
T
T
S
G
T
P
S
C
Site 44
S785
T
K
P
N
G
T
T
S
G
T
P
S
C
S
W
Site 45
T787
P
N
G
T
T
S
G
T
P
S
C
S
W
K
D
Site 46
S789
G
T
T
S
G
T
P
S
C
S
W
K
D
L
K
Site 47
S791
T
S
G
T
P
S
C
S
W
K
D
L
K
T
M
Site 48
Y819
T
L
S
R
Q
I
D
Y
Y
C
R
L
D
C
L
Site 49
Y820
L
S
R
Q
I
D
Y
Y
C
R
L
D
C
L
W
Site 50
T840
K
E
H
E
E
F
E
T
M
E
N
V
N
R
L
Site 51
Y871
D
K
L
N
E
D
W
Y
H
Q
S
Y
D
C
V
Site 52
Y892
V
P
D
F
K
V
F
Y
T
E
C
D
V
N
K
Site 53
S925
L
L
L
K
P
K
F
S
G
V
E
K
I
K
T
Site 54
T932
S
G
V
E
K
I
K
T
I
G
S
T
Y
M
A
Site 55
S982
L
D
G
I
N
R
H
S
F
N
S
F
R
L
R
Site 56
S985
I
N
R
H
S
F
N
S
F
R
L
R
V
G
I
Site 57
Y1009
I
G
A
R
K
P
Q
Y
D
I
W
G
N
T
V
Site 58
S1024
N
V
A
S
R
M
E
S
T
G
E
L
G
K
I
Site 59
Y1065
G
K
G
E
L
R
T
Y
F
V
C
T
D
T
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation