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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
HDGF
Full Name:
Hepatoma-derived growth factor
Alias:
High-mobility group protein 1- like 2; High-mobility group protein 1-like; High-mobility group protein 1-like 2; HMG1L2; HMG-1L2
Type:
Secreted protein, growth factor
Mass (Da):
26788
Number AA:
240
UniProt ID:
P51858
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005615
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003677
GO:0008083
GO:0008201
PhosphoSite+
KinaseNET
Biological Process:
GO:0008283
GO:0045449
GO:0007165
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S2
_
_
_
_
_
_
M
S
R
S
N
R
Q
K
E
Site 2
Y10
R
S
N
R
Q
K
E
Y
K
C
G
D
L
V
F
Site 3
Y45
V
K
S
T
A
N
K
Y
Q
V
F
F
F
G
T
Site 4
Y66
G
P
K
D
L
F
P
Y
E
E
S
K
E
K
F
Site 5
T94
W
E
I
E
N
N
P
T
V
K
A
S
G
Y
Q
Site 6
S98
N
N
P
T
V
K
A
S
G
Y
Q
S
S
Q
K
Site 7
Y100
P
T
V
K
A
S
G
Y
Q
S
S
Q
K
K
S
Site 8
S102
V
K
A
S
G
Y
Q
S
S
Q
K
K
S
C
V
Site 9
S103
K
A
S
G
Y
Q
S
S
Q
K
K
S
C
V
E
Site 10
S107
Y
Q
S
S
Q
K
K
S
C
V
E
E
P
E
P
Site 11
S132
K
K
G
N
A
E
G
S
S
D
E
E
G
K
L
Site 12
S133
K
G
N
A
E
G
S
S
D
E
E
G
K
L
V
Site 13
S165
A
G
D
L
L
E
D
S
P
K
R
P
K
E
A
Site 14
S199
P
M
E
V
E
K
N
S
T
P
S
E
P
G
S
Site 15
T200
M
E
V
E
K
N
S
T
P
S
E
P
G
S
G
Site 16
S202
V
E
K
N
S
T
P
S
E
P
G
S
G
R
G
Site 17
S206
S
T
P
S
E
P
G
S
G
R
G
P
P
Q
E
Site 18
T225
E
D
E
E
E
E
A
T
K
E
D
A
E
A
P
Site 19
S239
P
G
I
R
D
H
E
S
L
_
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation