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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
Calponin 1
Full Name:
Calponin-1
Alias:
Basic calponin; calponin 1, basic, smooth muscle; Calponin H1, smooth muscle; CLP1; CNN1; Sm-Calp; SMCC
Type:
Contractile protein; Myosin binding protein; Actin binding protein
Mass (Da):
33170
Number AA:
297
UniProt ID:
P51911
International Prot ID:
IPI00021264
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0003779
GO:0005516
PhosphoSite+
KinaseNET
Biological Process:
GO:0031032
GO:0006940
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S2
_
_
_
_
_
_
M
S
S
A
H
F
N
R
G
Site 2
S3
_
_
_
_
_
M
S
S
A
H
F
N
R
G
P
Site 3
Y12
H
F
N
R
G
P
A
Y
G
L
S
A
E
V
K
Site 4
S15
R
G
P
A
Y
G
L
S
A
E
V
K
N
K
L
Site 5
Y26
K
N
K
L
A
Q
K
Y
D
H
Q
R
E
Q
E
Site 6
T42
R
E
W
I
E
G
V
T
G
R
R
I
G
N
N
Site 7
S71
I
N
K
L
Q
P
G
S
V
K
K
I
N
E
S
Site 8
Y98
F
I
K
A
I
T
K
Y
G
V
K
P
H
D
I
Site 9
T118
L
F
E
N
T
N
H
T
Q
V
Q
S
T
L
L
Site 10
T133
A
L
A
S
M
A
K
T
K
G
N
K
V
N
V
Site 11
Y144
K
V
N
V
G
V
K
Y
A
E
K
Q
E
R
K
Site 12
T170
I
I
G
L
Q
M
G
T
N
K
F
A
S
Q
Q
Site 13
S175
M
G
T
N
K
F
A
S
Q
Q
G
M
T
A
Y
Site 14
T180
F
A
S
Q
Q
G
M
T
A
Y
G
T
R
R
H
Site 15
Y182
S
Q
Q
G
M
T
A
Y
G
T
R
R
H
L
Y
Site 16
T184
Q
G
M
T
A
Y
G
T
R
R
H
L
Y
D
P
Site 17
Y189
Y
G
T
R
R
H
L
Y
D
P
K
L
G
T
D
Site 18
T203
D
Q
P
L
D
Q
A
T
I
S
L
Q
M
G
T
Site 19
S205
P
L
D
Q
A
T
I
S
L
Q
M
G
T
N
K
Site 20
S215
M
G
T
N
K
G
A
S
Q
A
G
M
T
A
P
Site 21
T224
A
G
M
T
A
P
G
T
K
R
Q
I
F
E
P
Site 22
S249
N
V
S
L
Q
M
G
S
N
K
G
A
S
Q
R
Site 23
S254
M
G
S
N
K
G
A
S
Q
R
G
M
T
V
Y
Site 24
T259
G
A
S
Q
R
G
M
T
V
Y
G
L
P
R
Q
Site 25
Y261
S
Q
R
G
M
T
V
Y
G
L
P
R
Q
V
Y
Site 26
Y268
Y
G
L
P
R
Q
V
Y
D
P
K
Y
C
L
T
Site 27
Y272
R
Q
V
Y
D
P
K
Y
C
L
T
P
E
Y
P
Site 28
T275
Y
D
P
K
Y
C
L
T
P
E
Y
P
E
L
G
Site 29
Y278
K
Y
C
L
T
P
E
Y
P
E
L
G
E
P
A
Site 30
Y293
H
N
H
H
A
H
N
Y
Y
N
S
A
_
_
_
Site 31
Y294
N
H
H
A
H
N
Y
Y
N
S
A
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation