PhosphoNET

           
Protein Info 
   
Short Name:  UBE2E1
Full Name:  Ubiquitin-conjugating enzyme E2 E1
Alias:  UB2E1; UB2E1, ubiquitin-protein ligase E1; UbcH6; Ubiquitin carrier protein E1; Ubiquitin-conjugating enzyme E2E 1 (UBC4/5); Ubiquitin-protein ligase E1
Type:  EC 6.3.2.19; Ubiquitin conjugating system; Ubiquitin ligase; Ligase
Mass (Da):  21404
Number AA:  193
UniProt ID:  P51965
International Prot ID:  IPI00021346
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005829  GO:0005654  GO:0000151 Uniprot OncoNet
Molecular Function:  GO:0005524  GO:0042296  GO:0005515 PhosphoSite+ KinaseNET
Biological Process:  GO:0032020  GO:0031145  GO:0033523 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S2______MSDDDSRAS
Site 2S6__MSDDDSRASTSSS
Site 3S9SDDDSRASTSSSSSS
Site 4T10DDDSRASTSSSSSSS
Site 5S11DDSRASTSSSSSSSS
Site 6S12DSRASTSSSSSSSSN
Site 7S13SRASTSSSSSSSSNQ
Site 8S14RASTSSSSSSSSNQQ
Site 9S15ASTSSSSSSSSNQQT
Site 10S16STSSSSSSSSNQQTE
Site 11S17TSSSSSSSSNQQTEK
Site 12S18SSSSSSSSNQQTEKE
Site 13T22SSSSNQQTEKETNTP
Site 14T28QTEKETNTPKKKESK
Site 15S34NTPKKKESKVSMSKN
Site 16S37KKKESKVSMSKNSKL
Site 17S39KESKVSMSKNSKLLS
Site 18S42KVSMSKNSKLLSTSA
Site 19S46SKNSKLLSTSAKRIQ
Site 20T60QKELADITLDPPPNC
Site 21S68LDPPPNCSAGPKGDN
Site 22Y77GPKGDNIYEWRSTIL
Site 23S81DNIYEWRSTILGPPG
Site 24T82NIYEWRSTILGPPGS
Site 25Y106DITFTPEYPFKPPKV
Site 26T114PFKPPKVTFRTRIYH
Site 27Y120VTFRTRIYHCNINSQ
Site 28S140DILKDNWSPALTISK
Site 29Y173VGSIATQYMTNRAEH
Site 30T175SIATQYMTNRAEHDR
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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