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Updated November 2019
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Protein Info
Short Name:
DGKE
Full Name:
Diacylglycerol kinase epsilon
Alias:
Diglyceride kinase epsilon
Type:
Mass (Da):
63927
Number AA:
567
UniProt ID:
P52429
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S11
E
R
R
P
A
P
G
S
P
S
E
G
L
F
A
Site 2
T65
S
K
H
G
W
R
D
T
D
L
F
S
Q
P
T
Site 3
S190
K
N
L
I
I
P
P
S
Y
L
T
S
I
N
Q
Site 4
S194
I
P
P
S
Y
L
T
S
I
N
Q
M
R
K
D
Site 5
T204
Q
M
R
K
D
K
K
T
D
Y
E
V
L
A
S
Site 6
Y206
R
K
D
K
K
T
D
Y
E
V
L
A
S
K
L
Site 7
S211
T
D
Y
E
V
L
A
S
K
L
G
K
Q
W
T
Site 8
S228
I
I
L
A
N
S
R
S
G
T
N
M
G
E
G
Site 9
T230
L
A
N
S
R
S
G
T
N
M
G
E
G
L
L
Site 10
T255
Q
V
F
D
V
T
K
T
P
P
I
K
A
L
Q
Site 11
Y301
K
I
K
G
Q
E
K
Y
I
P
Q
V
A
V
L
Site 12
S317
L
G
T
G
N
D
L
S
N
T
L
G
W
G
T
Site 13
T319
T
G
N
D
L
S
N
T
L
G
W
G
T
G
Y
Site 14
Y373
K
E
F
T
M
N
N
Y
F
S
V
G
P
D
A
Site 15
S395
A
H
R
E
K
A
P
S
L
F
S
S
R
I
L
Site 16
S398
E
K
A
P
S
L
F
S
S
R
I
L
N
K
A
Site 17
S399
K
A
P
S
L
F
S
S
R
I
L
N
K
A
V
Site 18
Y407
R
I
L
N
K
A
V
Y
L
F
Y
G
T
K
D
Site 19
Y467
E
G
M
G
D
E
T
Y
P
L
A
R
H
D
D
Site 20
T531
P
W
A
Q
G
P
C
T
V
T
I
T
H
K
T
Site 21
T533
A
Q
G
P
C
T
V
T
I
T
H
K
T
H
A
Site 22
Y544
K
T
H
A
M
M
L
Y
F
S
G
E
Q
T
D
Site 23
T550
L
Y
F
S
G
E
Q
T
D
D
D
I
S
S
T
Site 24
S555
E
Q
T
D
D
D
I
S
S
T
S
D
Q
E
D
Site 25
S556
Q
T
D
D
D
I
S
S
T
S
D
Q
E
D
I
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation