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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
AGFG1
Full Name:
Arf-GAP domain and FG repeats-containing protein 1
Alias:
ArfGAP with FG repeats 1; HIV-1 Rev-binding protein; HIV-1 Rev-interacting protein; HRB; Nucleoporin-like protein RIP; NUPL; RAB; Rev interacting protein; Rev/Rex activation domain-binding protein
Type:
RNA binding protein
Mass (Da):
58260
Number AA:
562
UniProt ID:
P52594
International Prot ID:
IPI00607616
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005794
GO:0016023
GO:0005643
Uniprot
OncoNet
Molecular Function:
GO:0008060
GO:0003677
GO:0003723
PhosphoSite+
KinaseNET
Biological Process:
GO:0030154
GO:0006406
GO:0007275
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T21
L
K
M
L
R
D
M
T
G
L
P
H
N
R
K
Site 2
T38
D
C
D
Q
R
G
P
T
Y
V
N
M
T
V
G
Site 3
Y39
C
D
Q
R
G
P
T
Y
V
N
M
T
V
G
S
Site 4
S55
V
C
T
S
C
S
G
S
L
R
G
L
N
P
P
Site 5
S67
N
P
P
H
R
V
K
S
I
S
M
T
T
F
T
Site 6
S69
P
H
R
V
K
S
I
S
M
T
T
F
T
Q
Q
Site 7
T71
R
V
K
S
I
S
M
T
T
F
T
Q
Q
E
I
Site 8
S101
L
G
L
F
D
D
R
S
S
A
I
P
D
F
R
Site 9
S102
G
L
F
D
D
R
S
S
A
I
P
D
F
R
D
Site 10
Y121
K
E
F
L
Q
E
K
Y
E
K
K
R
W
Y
V
Site 11
Y127
K
Y
E
K
K
R
W
Y
V
P
P
E
Q
A
K
Site 12
S144
A
S
V
H
A
S
I
S
G
S
S
A
S
S
T
Site 13
S146
V
H
A
S
I
S
G
S
S
A
S
S
T
S
S
Site 14
S147
H
A
S
I
S
G
S
S
A
S
S
T
S
S
T
Site 15
S149
S
I
S
G
S
S
A
S
S
T
S
S
T
P
E
Site 16
S150
I
S
G
S
S
A
S
S
T
S
S
T
P
E
V
Site 17
T151
S
G
S
S
A
S
S
T
S
S
T
P
E
V
K
Site 18
S152
G
S
S
A
S
S
T
S
S
T
P
E
V
K
P
Site 19
S153
S
S
A
S
S
T
S
S
T
P
E
V
K
P
L
Site 20
T154
S
A
S
S
T
S
S
T
P
E
V
K
P
L
K
Site 21
S162
P
E
V
K
P
L
K
S
L
L
G
D
S
A
P
Site 22
S167
L
K
S
L
L
G
D
S
A
P
T
L
H
L
N
Site 23
T170
L
L
G
D
S
A
P
T
L
H
L
N
K
G
T
Site 24
T177
T
L
H
L
N
K
G
T
P
S
Q
S
P
V
V
Site 25
S179
H
L
N
K
G
T
P
S
Q
S
P
V
V
G
R
Site 26
S181
N
K
G
T
P
S
Q
S
P
V
V
G
R
S
Q
Site 27
S201
K
K
Q
F
D
L
L
S
D
L
G
S
D
I
F
Site 28
S249
N
F
D
A
F
G
Q
S
S
G
S
S
N
F
G
Site 29
S250
F
D
A
F
G
Q
S
S
G
S
S
N
F
G
G
Site 30
S252
A
F
G
Q
S
S
G
S
S
N
F
G
G
F
P
Site 31
S253
F
G
Q
S
S
G
S
S
N
F
G
G
F
P
T
Site 32
T260
S
N
F
G
G
F
P
T
A
S
H
S
P
F
Q
Site 33
S262
F
G
G
F
P
T
A
S
H
S
P
F
Q
P
Q
Site 34
S264
G
F
P
T
A
S
H
S
P
F
Q
P
Q
T
T
Site 35
T270
H
S
P
F
Q
P
Q
T
T
G
G
S
A
A
S
Site 36
S277
T
T
G
G
S
A
A
S
V
N
A
N
F
A
H
Site 37
S291
H
F
D
N
F
P
K
S
S
S
A
D
F
G
T
Site 38
S293
D
N
F
P
K
S
S
S
A
D
F
G
T
F
N
Site 39
T298
S
S
S
A
D
F
G
T
F
N
T
S
Q
S
H
Site 40
S302
D
F
G
T
F
N
T
S
Q
S
H
Q
T
A
S
Site 41
S304
G
T
F
N
T
S
Q
S
H
Q
T
A
S
A
V
Site 42
S309
S
Q
S
H
Q
T
A
S
A
V
S
K
V
S
T
Site 43
T316
S
A
V
S
K
V
S
T
N
K
A
G
L
Q
T
Site 44
Y327
G
L
Q
T
A
D
K
Y
A
A
L
A
N
L
D
Site 45
S338
A
N
L
D
N
I
F
S
A
G
Q
G
G
D
Q
Site 46
S347
G
Q
G
G
D
Q
G
S
G
F
G
T
T
G
K
Site 47
T351
D
Q
G
S
G
F
G
T
T
G
K
A
P
V
G
Site 48
S362
A
P
V
G
S
V
V
S
V
P
S
Q
S
S
A
Site 49
S365
G
S
V
V
S
V
P
S
Q
S
S
A
S
S
D
Site 50
S367
V
V
S
V
P
S
Q
S
S
A
S
S
D
K
Y
Site 51
S368
V
S
V
P
S
Q
S
S
A
S
S
D
K
Y
A
Site 52
S371
P
S
Q
S
S
A
S
S
D
K
Y
A
A
L
A
Site 53
Y374
S
S
A
S
S
D
K
Y
A
A
L
A
E
L
D
Site 54
S385
A
E
L
D
S
V
F
S
S
A
A
T
S
S
N
Site 55
S386
E
L
D
S
V
F
S
S
A
A
T
S
S
N
A
Site 56
T389
S
V
F
S
S
A
A
T
S
S
N
A
Y
T
S
Site 57
S390
V
F
S
S
A
A
T
S
S
N
A
Y
T
S
T
Site 58
S391
F
S
S
A
A
T
S
S
N
A
Y
T
S
T
S
Site 59
Y394
A
A
T
S
S
N
A
Y
T
S
T
S
N
A
S
Site 60
T395
A
T
S
S
N
A
Y
T
S
T
S
N
A
S
S
Site 61
S396
T
S
S
N
A
Y
T
S
T
S
N
A
S
S
N
Site 62
T397
S
S
N
A
Y
T
S
T
S
N
A
S
S
N
V
Site 63
S398
S
N
A
Y
T
S
T
S
N
A
S
S
N
V
F
Site 64
S402
T
S
T
S
N
A
S
S
N
V
F
G
T
V
P
Site 65
S420
S
A
Q
T
Q
P
A
S
S
S
V
P
A
P
F
Site 66
S421
A
Q
T
Q
P
A
S
S
S
V
P
A
P
F
G
Site 67
S422
Q
T
Q
P
A
S
S
S
V
P
A
P
F
G
A
Site 68
S447
A
G
P
S
V
A
S
S
T
N
P
F
Q
T
N
Site 69
T459
Q
T
N
A
R
G
A
T
A
A
T
F
G
T
A
Site 70
T476
S
M
P
T
G
F
G
T
P
A
P
Y
S
L
P
Site 71
Y480
G
F
G
T
P
A
P
Y
S
L
P
T
S
F
S
Site 72
S481
F
G
T
P
A
P
Y
S
L
P
T
S
F
S
G
Site 73
S485
A
P
Y
S
L
P
T
S
F
S
G
S
F
Q
Q
Site 74
S487
Y
S
L
P
T
S
F
S
G
S
F
Q
Q
P
A
Site 75
S489
L
P
T
S
F
S
G
S
F
Q
Q
P
A
F
P
Site 76
S508
F
P
Q
Q
T
A
F
S
Q
Q
P
N
G
A
G
Site 77
T544
V
S
S
N
P
F
M
T
G
A
P
T
G
Q
F
Site 78
T553
A
P
T
G
Q
F
P
T
G
S
S
S
T
N
P
Site 79
S555
T
G
Q
F
P
T
G
S
S
S
T
N
P
F
L
Site 80
S557
Q
F
P
T
G
S
S
S
T
N
P
F
L
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation