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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ZNF135
Full Name:
Zinc finger protein 135
Alias:
Zinc finger protein 61;Zinc finger protein 78-like 1
Type:
Mass (Da):
75261
Number AA:
658
UniProt ID:
P52742
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S8
M
T
P
G
V
R
V
S
T
D
P
E
Q
V
T
Site 2
T9
T
P
G
V
R
V
S
T
D
P
E
Q
V
T
F
Site 3
T15
S
T
D
P
E
Q
V
T
F
E
D
V
V
V
D
Site 4
S24
E
D
V
V
V
D
F
S
Q
E
E
W
G
Q
L
Site 5
Y39
K
P
A
Q
R
T
L
Y
R
D
V
M
L
D
T
Site 6
S77
A
E
L
W
A
V
E
S
R
L
P
Q
G
V
Y
Site 7
Y84
S
R
L
P
Q
G
V
Y
P
D
L
E
T
R
P
Site 8
S96
T
R
P
K
V
K
L
S
V
L
K
Q
G
I
S
Site 9
S103
S
V
L
K
Q
G
I
S
E
E
I
S
N
S
V
Site 10
Y123
F
L
W
D
G
L
W
Y
C
R
G
E
D
T
E
Site 11
S136
T
E
G
H
W
E
W
S
C
E
S
L
E
S
L
Site 12
S139
H
W
E
W
S
C
E
S
L
E
S
L
A
V
P
Site 13
S170
N
G
F
G
E
N
I
S
L
N
P
D
L
P
H
Site 14
T181
D
L
P
H
Q
P
M
T
P
E
R
Q
S
P
H
Site 15
S186
P
M
T
P
E
R
Q
S
P
H
T
W
G
T
R
Site 16
T189
P
E
R
Q
S
P
H
T
W
G
T
R
G
K
R
Site 17
T207
D
L
N
V
L
Q
K
T
C
V
K
E
K
P
Y
Site 18
Y214
T
C
V
K
E
K
P
Y
K
C
Q
E
C
G
K
Site 19
S224
Q
E
C
G
K
A
F
S
H
S
S
A
L
I
E
Site 20
S226
C
G
K
A
F
S
H
S
S
A
L
I
E
H
H
Site 21
S227
G
K
A
F
S
H
S
S
A
L
I
E
H
H
R
Site 22
T235
A
L
I
E
H
H
R
T
H
T
G
E
R
P
Y
Site 23
T237
I
E
H
H
R
T
H
T
G
E
R
P
Y
E
C
Site 24
Y242
T
H
T
G
E
R
P
Y
E
C
H
E
C
L
K
Site 25
S254
C
L
K
G
F
R
N
S
S
A
L
T
K
H
Q
Site 26
S255
L
K
G
F
R
N
S
S
A
L
T
K
H
Q
R
Site 27
T258
F
R
N
S
S
A
L
T
K
H
Q
R
I
H
T
Site 28
T265
T
K
H
Q
R
I
H
T
G
E
K
P
Y
K
C
Site 29
T291
P
L
I
Q
H
Q
R
T
H
T
G
E
K
P
Y
Site 30
T293
I
Q
H
Q
R
T
H
T
G
E
K
P
Y
E
C
Site 31
Y298
T
H
T
G
E
K
P
Y
E
C
S
E
C
G
K
Site 32
S301
G
E
K
P
Y
E
C
S
E
C
G
K
S
F
S
Site 33
S306
E
C
S
E
C
G
K
S
F
S
F
R
S
S
F
Site 34
S308
S
E
C
G
K
S
F
S
F
R
S
S
F
S
Q
Site 35
S311
G
K
S
F
S
F
R
S
S
F
S
Q
H
E
R
Site 36
S312
K
S
F
S
F
R
S
S
F
S
Q
H
E
R
T
Site 37
S314
F
S
F
R
S
S
F
S
Q
H
E
R
T
H
T
Site 38
T319
S
F
S
Q
H
E
R
T
H
T
G
E
K
P
Y
Site 39
T321
S
Q
H
E
R
T
H
T
G
E
K
P
Y
E
C
Site 40
S329
G
E
K
P
Y
E
C
S
E
C
G
K
A
F
R
Site 41
T342
F
R
Q
S
I
H
L
T
Q
H
L
R
I
H
T
Site 42
T349
T
Q
H
L
R
I
H
T
G
E
K
P
Y
Q
C
Site 43
Y354
I
H
T
G
E
K
P
Y
Q
C
G
E
C
G
K
Site 44
S364
G
E
C
G
K
A
F
S
H
S
S
S
L
T
K
Site 45
S366
C
G
K
A
F
S
H
S
S
S
L
T
K
H
Q
Site 46
S367
G
K
A
F
S
H
S
S
S
L
T
K
H
Q
R
Site 47
S368
K
A
F
S
H
S
S
S
L
T
K
H
Q
R
I
Site 48
T370
F
S
H
S
S
S
L
T
K
H
Q
R
I
H
T
Site 49
T377
T
K
H
Q
R
I
H
T
G
E
K
P
Y
E
C
Site 50
Y382
I
H
T
G
E
K
P
Y
E
C
H
E
C
G
K
Site 51
T395
G
K
A
F
T
Q
I
T
P
L
I
Q
H
Q
R
Site 52
Y410
T
H
T
G
E
K
P
Y
E
C
G
E
C
G
K
Site 53
S420
G
E
C
G
K
A
F
S
Q
S
T
L
L
T
E
Site 54
T426
F
S
Q
S
T
L
L
T
E
H
R
R
I
H
T
Site 55
T433
T
E
H
R
R
I
H
T
G
E
K
P
Y
G
C
Site 56
Y438
I
H
T
G
E
K
P
Y
G
C
N
E
C
G
K
Site 57
T446
G
C
N
E
C
G
K
T
F
S
H
S
S
S
L
Site 58
S448
N
E
C
G
K
T
F
S
H
S
S
S
L
S
Q
Site 59
S450
C
G
K
T
F
S
H
S
S
S
L
S
Q
H
E
Site 60
S451
G
K
T
F
S
H
S
S
S
L
S
Q
H
E
R
Site 61
S452
K
T
F
S
H
S
S
S
L
S
Q
H
E
R
T
Site 62
S454
F
S
H
S
S
S
L
S
Q
H
E
R
T
H
T
Site 63
T459
S
L
S
Q
H
E
R
T
H
T
G
E
K
P
Y
Site 64
Y466
T
H
T
G
E
K
P
Y
E
C
S
Q
C
G
K
Site 65
S469
G
E
K
P
Y
E
C
S
Q
C
G
K
A
F
R
Site 66
T479
G
K
A
F
R
Q
S
T
H
L
T
Q
H
Q
R
Site 67
T489
T
Q
H
Q
R
I
H
T
G
E
K
P
Y
E
C
Site 68
Y494
I
H
T
G
E
K
P
Y
E
C
N
D
C
G
K
Site 69
S504
N
D
C
G
K
A
F
S
H
S
S
S
L
T
K
Site 70
Y522
I
H
T
G
E
K
P
Y
E
C
N
Q
C
G
R
Site 71
S532
N
Q
C
G
R
A
F
S
Q
L
A
P
L
I
Q
Site 72
T545
I
Q
H
Q
R
I
H
T
G
E
K
P
Y
E
C
Site 73
S560
N
Q
C
G
R
A
F
S
Q
S
S
L
L
I
E
Site 74
S562
C
G
R
A
F
S
Q
S
S
L
L
I
E
H
Q
Site 75
S563
G
R
A
F
S
Q
S
S
L
L
I
E
H
Q
R
Site 76
T573
I
E
H
Q
R
I
H
T
K
E
K
P
Y
G
C
Site 77
Y578
I
H
T
K
E
K
P
Y
G
C
N
E
C
G
K
Site 78
S586
G
C
N
E
C
G
K
S
F
S
H
S
S
S
L
Site 79
S588
N
E
C
G
K
S
F
S
H
S
S
S
L
S
Q
Site 80
S590
C
G
K
S
F
S
H
S
S
S
L
S
Q
H
E
Site 81
S591
G
K
S
F
S
H
S
S
S
L
S
Q
H
E
R
Site 82
S592
K
S
F
S
H
S
S
S
L
S
Q
H
E
R
T
Site 83
Y606
T
H
T
G
E
K
P
Y
E
C
H
D
C
G
K
Site 84
S618
C
G
K
S
F
R
Q
S
T
H
L
T
Q
H
R
Site 85
T619
G
K
S
F
R
Q
S
T
H
L
T
Q
H
R
R
Site 86
T622
F
R
Q
S
T
H
L
T
Q
H
R
R
I
H
T
Site 87
T629
T
Q
H
R
R
I
H
T
G
E
K
P
Y
A
C
Site 88
Y634
I
H
T
G
E
K
P
Y
A
C
R
D
C
G
K
Site 89
T644
R
D
C
G
K
A
F
T
H
S
S
S
L
T
K
Site 90
S646
C
G
K
A
F
T
H
S
S
S
L
T
K
H
Q
Site 91
S647
G
K
A
F
T
H
S
S
S
L
T
K
H
Q
R
Site 92
S648
K
A
F
T
H
S
S
S
L
T
K
H
Q
R
T
Site 93
T650
F
T
H
S
S
S
L
T
K
H
Q
R
T
H
T
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation