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Updated November 2019
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Protein Info
Short Name:
ZNF142
Full Name:
Zinc finger protein 142
Alias:
HA4654; KIAA0236; PHZ-49; Zinc finger 142; ZN142
Type:
Transcription factor
Mass (Da):
187866
Number AA:
1687
UniProt ID:
P52746
International Prot ID:
IPI00005004
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003700
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0045449
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S8
M
T
D
P
L
L
D
S
Q
P
A
S
S
T
G
Site 2
S12
L
L
D
S
Q
P
A
S
S
T
G
E
M
D
G
Site 3
S42
G
I
L
G
P
V
Q
S
P
C
P
S
R
D
P
Site 4
S46
P
V
Q
S
P
C
P
S
R
D
P
A
P
I
P
Site 5
T66
L
L
V
E
A
T
A
T
E
E
G
P
G
N
M
Site 6
T85
E
T
V
A
G
T
L
T
P
G
A
P
G
E
T
Site 7
T92
T
P
G
A
P
G
E
T
P
A
P
K
L
P
P
Site 8
S105
P
P
G
E
R
E
P
S
Q
E
A
G
T
P
L
Site 9
T110
E
P
S
Q
E
A
G
T
P
L
P
G
Q
E
T
Site 10
S129
N
V
E
K
E
E
K
S
D
T
Q
K
D
S
Q
Site 11
T131
E
K
E
E
K
S
D
T
Q
K
D
S
Q
K
A
Site 12
S135
K
S
D
T
Q
K
D
S
Q
K
A
V
D
K
G
Site 13
S154
R
L
E
G
D
V
V
S
G
T
E
S
L
F
K
Site 14
S158
D
V
V
S
G
T
E
S
L
F
K
T
H
M
C
Site 15
T162
G
T
E
S
L
F
K
T
H
M
C
P
E
C
K
Site 16
S204
Q
K
F
F
T
S
K
S
K
L
K
T
H
L
L
Site 17
T208
T
S
K
S
K
L
K
T
H
L
L
R
E
L
G
Site 18
Y226
H
H
C
P
L
C
H
Y
S
A
V
E
R
N
A
Site 19
Y253
S
N
F
Y
S
D
T
Y
A
C
P
V
C
R
E
Site 20
S265
C
R
E
E
F
R
L
S
Q
A
L
K
E
H
L
Site 21
S274
A
L
K
E
H
L
K
S
H
T
A
A
A
A
A
Site 22
Y295
C
F
Q
E
G
C
S
Y
A
A
P
D
R
K
A
Site 23
S369
K
K
Q
G
H
P
G
S
E
E
L
R
C
T
F
Site 24
Y387
A
T
F
N
P
V
A
Y
Q
D
H
V
G
K
M
Site 25
T424
I
R
H
M
L
L
H
T
G
E
K
P
H
K
C
Site 26
Y443
F
T
C
R
D
V
S
Y
L
S
K
H
M
L
T
Site 27
S445
C
R
D
V
S
Y
L
S
K
H
M
L
T
H
S
Site 28
T450
Y
L
S
K
H
M
L
T
H
S
N
T
K
D
Y
Site 29
Y457
T
H
S
N
T
K
D
Y
M
C
T
E
C
G
Y
Site 30
Y471
Y
V
T
K
W
K
H
Y
L
R
V
H
M
R
K
Site 31
Y485
K
H
A
G
D
L
R
Y
Q
C
N
Q
C
S
Y
Site 32
S501
C
H
R
A
D
Q
L
S
S
H
K
L
R
H
Q
Site 33
Y525
A
F
A
C
K
R
K
Y
E
L
Q
K
H
M
A
Site 34
S533
E
L
Q
K
H
M
A
S
Q
H
H
P
G
T
P
Site 35
T539
A
S
Q
H
H
P
G
T
P
A
P
L
Y
P
C
Site 36
Y544
P
G
T
P
A
P
L
Y
P
C
H
Y
C
S
Y
Site 37
Y548
A
P
L
Y
P
C
H
Y
C
S
Y
Q
S
R
H
Site 38
T568
S
H
E
N
C
K
H
T
R
L
R
E
F
H
C
Site 39
T586
D
Y
R
T
F
S
N
T
T
L
L
F
H
K
R
Site 40
Y598
H
K
R
K
A
H
G
Y
V
P
G
D
Q
A
W
Site 41
Y609
D
Q
A
W
Q
L
R
Y
A
S
Q
E
P
E
G
Site 42
S611
A
W
Q
L
R
Y
A
S
Q
E
P
E
G
A
M
Site 43
T622
E
G
A
M
Q
G
P
T
P
P
P
D
S
E
P
Site 44
S627
G
P
T
P
P
P
D
S
E
P
S
N
Q
L
S
Site 45
S630
P
P
P
D
S
E
P
S
N
Q
L
S
A
R
P
Site 46
S634
S
E
P
S
N
Q
L
S
A
R
P
E
G
P
G
Site 47
T646
G
P
G
H
E
P
G
T
V
V
D
P
S
L
D
Site 48
S651
P
G
T
V
V
D
P
S
L
D
Q
A
L
P
E
Site 49
T665
E
M
S
E
E
V
N
T
G
R
Q
E
G
S
E
Site 50
S671
N
T
G
R
Q
E
G
S
E
A
P
H
G
G
D
Site 51
S682
H
G
G
D
L
G
G
S
P
S
P
A
E
V
E
Site 52
S684
G
D
L
G
G
S
P
S
P
A
E
V
E
E
G
Site 53
T694
E
V
E
E
G
S
C
T
L
H
L
E
A
L
G
Site 54
T708
G
V
E
L
E
S
V
T
E
P
P
L
E
E
V
Site 55
T718
P
L
E
E
V
T
E
T
A
P
M
E
F
R
P
Site 56
S740
G
L
E
G
P
E
L
S
S
F
E
G
I
G
T
Site 57
S741
L
E
G
P
E
L
S
S
F
E
G
I
G
T
S
Site 58
T747
S
S
F
E
G
I
G
T
S
D
L
G
A
E
E
Site 59
S748
S
F
E
G
I
G
T
S
D
L
G
A
E
E
N
Site 60
S763
P
L
L
E
K
P
V
S
E
P
S
T
N
P
P
Site 61
S766
E
K
P
V
S
E
P
S
T
N
P
P
S
L
E
Site 62
T767
K
P
V
S
E
P
S
T
N
P
P
S
L
E
E
Site 63
S771
E
P
S
T
N
P
P
S
L
E
E
A
P
N
N
Site 64
T782
A
P
N
N
W
V
G
T
F
K
T
T
P
P
A
Site 65
T785
N
W
V
G
T
F
K
T
T
P
P
A
E
T
A
Site 66
T786
W
V
G
T
F
K
T
T
P
P
A
E
T
A
P
Site 67
S800
P
L
P
P
L
P
E
S
E
S
L
L
K
A
L
Site 68
S802
P
P
L
P
E
S
E
S
L
L
K
A
L
R
R
Site 69
S874
L
C
P
E
C
G
A
S
F
K
Q
Q
R
G
L
Site 70
S882
F
K
Q
Q
R
G
L
S
T
H
L
L
K
K
C
Site 71
S904
K
G
L
P
R
P
D
S
P
I
P
L
Q
P
V
Site 72
T915
L
Q
P
V
L
P
G
T
Q
A
S
E
D
T
E
Site 73
S918
V
L
P
G
T
Q
A
S
E
D
T
E
S
G
K
Site 74
T921
G
T
Q
A
S
E
D
T
E
S
G
K
P
P
P
Site 75
S923
Q
A
S
E
D
T
E
S
G
K
P
P
P
A
S
Site 76
S930
S
G
K
P
P
P
A
S
Q
E
A
E
L
L
L
Site 77
T952
L
P
R
E
P
E
E
T
E
E
P
L
A
T
V
Site 78
T958
E
T
E
E
P
L
A
T
V
S
G
S
P
V
P
Site 79
S960
E
E
P
L
A
T
V
S
G
S
P
V
P
P
A
Site 80
T973
P
A
G
N
S
L
P
T
E
A
P
K
K
H
C
Site 81
S991
V
P
P
A
G
N
S
S
P
T
E
A
P
K
K
Site 82
T993
P
A
G
N
S
S
P
T
E
A
P
K
K
H
H
Site 83
S1011
V
P
P
A
G
N
S
S
P
T
E
A
L
K
K
Site 84
S1043
S
R
L
S
S
I
T
S
H
V
A
E
G
C
R
Site 85
T1061
G
G
G
G
K
R
G
T
P
Q
T
Q
P
D
V
Site 86
T1064
G
K
R
G
T
P
Q
T
Q
P
D
V
S
P
L
Site 87
S1069
P
Q
T
Q
P
D
V
S
P
L
S
N
G
D
S
Site 88
S1072
Q
P
D
V
S
P
L
S
N
G
D
S
A
P
P
Site 89
S1076
S
P
L
S
N
G
D
S
A
P
P
K
N
G
S
Site 90
S1083
S
A
P
P
K
N
G
S
T
E
S
S
S
G
D
Site 91
T1084
A
P
P
K
N
G
S
T
E
S
S
S
G
D
G
Site 92
S1086
P
K
N
G
S
T
E
S
S
S
G
D
G
D
T
Site 93
S1087
K
N
G
S
T
E
S
S
S
G
D
G
D
T
V
Site 94
S1088
N
G
S
T
E
S
S
S
G
D
G
D
T
V
L
Site 95
T1093
S
S
S
G
D
G
D
T
V
L
V
Q
K
Q
K
Site 96
S1105
K
Q
K
G
A
R
F
S
C
P
T
C
P
F
S
Site 97
S1138
E
S
G
E
L
H
C
S
L
C
P
F
T
A
P
Site 98
T1160
H
Q
K
R
R
H
P
T
A
A
P
A
R
G
P
Site 99
T1210
P
F
C
D
F
S
T
T
R
R
Y
R
L
E
A
Site 100
S1220
Y
R
L
E
A
H
Q
S
R
H
T
G
I
G
R
Site 101
T1223
E
A
H
Q
S
R
H
T
G
I
G
R
I
P
C
Site 102
S1231
G
I
G
R
I
P
C
S
S
C
P
Q
T
F
G
Site 103
S1232
I
G
R
I
P
C
S
S
C
P
Q
T
F
G
T
Site 104
T1236
P
C
S
S
C
P
Q
T
F
G
T
N
S
K
L
Site 105
T1239
S
C
P
Q
T
F
G
T
N
S
K
L
R
L
H
Site 106
S1241
P
Q
T
F
G
T
N
S
K
L
R
L
H
R
L
Site 107
T1254
R
L
R
V
H
D
K
T
P
T
H
F
C
P
L
Site 108
T1256
R
V
H
D
K
T
P
T
H
F
C
P
L
C
D
Site 109
Y1264
H
F
C
P
L
C
D
Y
S
G
Y
L
R
H
D
Site 110
Y1267
P
L
C
D
Y
S
G
Y
L
R
H
D
I
T
R
Site 111
T1283
V
N
S
C
H
Q
G
T
P
A
F
A
C
S
Q
Site 112
S1289
G
T
P
A
F
A
C
S
Q
C
E
A
Q
F
S
Site 113
S1296
S
Q
C
E
A
Q
F
S
S
E
T
A
L
K
Q
Site 114
S1319
P
A
Q
P
A
P
G
S
P
A
E
T
T
E
G
Site 115
T1323
A
P
G
S
P
A
E
T
T
E
G
P
L
H
C
Site 116
T1324
P
G
S
P
A
E
T
T
E
G
P
L
H
C
S
Site 117
S1339
R
C
G
L
L
C
P
S
P
A
S
L
R
G
H
Site 118
S1342
L
L
C
P
S
P
A
S
L
R
G
H
T
R
K
Site 119
T1347
P
A
S
L
R
G
H
T
R
K
Q
H
P
R
L
Site 120
Y1399
R
V
G
L
V
K
H
Y
L
E
Q
H
E
E
T
Site 121
Y1452
G
H
G
G
T
R
L
Y
K
C
T
D
C
A
Y
Site 122
T1455
G
T
R
L
Y
K
C
T
D
C
A
Y
S
T
K
Site 123
Y1459
Y
K
C
T
D
C
A
Y
S
T
K
N
R
Q
K
Site 124
T1475
T
W
H
S
R
I
H
T
G
E
K
P
Y
H
C
Site 125
Y1480
I
H
T
G
E
K
P
Y
H
C
H
L
C
P
Y
Site 126
Y1497
A
D
P
S
R
L
K
Y
H
M
R
I
H
K
E
Site 127
Y1508
I
H
K
E
E
R
K
Y
L
C
P
E
C
G
Y
Site 128
Y1536
K
H
T
G
L
K
P
Y
Q
C
P
E
C
E
Y
Site 129
Y1543
Y
Q
C
P
E
C
E
Y
C
T
N
R
A
D
A
Site 130
T1545
C
P
E
C
E
Y
C
T
N
R
A
D
A
L
R
Site 131
T1557
A
L
R
V
H
Q
E
T
R
H
R
E
A
R
A
Site 132
T1582
K
T
R
F
L
L
R
T
H
L
R
K
H
S
E
Site 133
S1588
R
T
H
L
R
K
H
S
E
A
K
P
Y
V
C
Site 134
Y1593
K
H
S
E
A
K
P
Y
V
C
N
V
C
H
R
Site 135
T1614
G
L
R
H
H
A
L
T
H
T
D
R
H
P
F
Site 136
T1616
R
H
H
A
L
T
H
T
D
R
H
P
F
F
C
Site 137
T1659
Q
G
V
G
K
D
P
T
T
P
T
V
H
L
H
Site 138
T1660
G
V
G
K
D
P
T
T
P
T
V
H
L
H
D
Site 139
T1662
G
K
D
P
T
T
P
T
V
H
L
H
D
V
Q
Site 140
S1674
D
V
Q
L
E
D
P
S
P
P
A
P
A
A
P
Site 141
T1683
P
A
P
A
A
P
H
T
G
P
E
G
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation