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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ZNF143
Full Name:
Zinc finger protein 143
Alias:
PHZ-1; SBF; SPH-binding factor; Staf; ZN143
Type:
Transcription factor
Mass (Da):
68896
Number AA:
638
UniProt ID:
P52747
International Prot ID:
IPI00305316
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003677
GO:0003709
GO:0003704
PhosphoSite+
KinaseNET
Biological Process:
GO:0006357
GO:0006359
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S10
L
A
Q
I
N
R
D
S
Q
G
M
T
E
F
P
Site 2
T14
N
R
D
S
Q
G
M
T
E
F
P
G
G
G
M
Site 3
Y87
L
E
D
G
S
A
A
Y
V
Q
H
V
P
I
P
Site 4
S96
Q
H
V
P
I
P
K
S
T
G
D
S
L
R
L
Site 5
S100
I
P
K
S
T
G
D
S
L
R
L
E
D
G
Q
Site 6
T115
A
V
Q
L
E
D
G
T
T
A
F
I
H
H
T
Site 7
T116
V
Q
L
E
D
G
T
T
A
F
I
H
H
T
S
Site 8
S126
I
H
H
T
S
K
D
S
Y
D
Q
S
A
L
Q
Site 9
Y127
H
H
T
S
K
D
S
Y
D
Q
S
A
L
Q
A
Site 10
S130
S
K
D
S
Y
D
Q
S
A
L
Q
A
V
Q
L
Site 11
T141
A
V
Q
L
E
D
G
T
T
A
Y
I
H
H
A
Site 12
T142
V
Q
L
E
D
G
T
T
A
Y
I
H
H
A
V
Site 13
T175
G
L
H
T
G
D
A
T
I
D
P
D
T
I
S
Site 14
T180
D
A
T
I
D
P
D
T
I
S
A
L
E
Q
Y
Site 15
S182
T
I
D
P
D
T
I
S
A
L
E
Q
Y
A
A
Site 16
S192
E
Q
Y
A
A
K
V
S
I
D
G
S
E
S
V
Site 17
S196
A
K
V
S
I
D
G
S
E
S
V
A
G
T
G
Site 18
T202
G
S
E
S
V
A
G
T
G
M
I
G
E
N
E
Site 19
T226
Q
G
H
A
T
R
V
T
A
K
S
Q
Q
S
G
Site 20
S229
A
T
R
V
T
A
K
S
Q
Q
S
G
E
K
A
Site 21
Y241
E
K
A
F
R
C
E
Y
D
G
C
G
K
L
Y
Site 22
Y248
Y
D
G
C
G
K
L
Y
T
T
A
H
H
L
K
Site 23
T249
D
G
C
G
K
L
Y
T
T
A
H
H
L
K
V
Site 24
T262
K
V
H
E
R
S
H
T
G
D
R
P
Y
Q
C
Site 25
Y267
S
H
T
G
D
R
P
Y
Q
C
E
H
A
G
C
Site 26
Y282
G
K
A
F
A
T
G
Y
G
L
K
S
H
V
R
Site 27
S286
A
T
G
Y
G
L
K
S
H
V
R
T
H
T
G
Site 28
T290
G
L
K
S
H
V
R
T
H
T
G
E
K
P
Y
Site 29
T292
K
S
H
V
R
T
H
T
G
E
K
P
Y
R
C
Site 30
S300
G
E
K
P
Y
R
C
S
E
D
N
C
T
K
S
Site 31
T305
R
C
S
E
D
N
C
T
K
S
F
K
T
S
G
Site 32
S307
S
E
D
N
C
T
K
S
F
K
T
S
G
D
L
Site 33
S311
C
T
K
S
F
K
T
S
G
D
L
Q
K
H
I
Site 34
T322
Q
K
H
I
R
T
H
T
G
E
R
P
F
K
C
Site 35
S337
P
F
E
G
C
G
R
S
F
T
T
S
N
I
R
Site 36
T339
E
G
C
G
R
S
F
T
T
S
N
I
R
K
V
Site 37
S341
C
G
R
S
F
T
T
S
N
I
R
K
V
H
V
Site 38
T352
K
V
H
V
R
T
H
T
G
E
R
P
Y
Y
C
Site 39
Y357
T
H
T
G
E
R
P
Y
Y
C
T
E
P
G
C
Site 40
Y358
H
T
G
E
R
P
Y
Y
C
T
E
P
G
C
G
Site 41
T360
G
E
R
P
Y
Y
C
T
E
P
G
C
G
R
A
Site 42
Y374
A
F
A
S
A
T
N
Y
K
N
H
V
R
I
H
Site 43
T382
K
N
H
V
R
I
H
T
G
E
K
P
Y
V
C
Site 44
Y387
I
H
T
G
E
K
P
Y
V
C
T
V
P
G
C
Site 45
T390
G
E
K
P
Y
V
C
T
V
P
G
C
D
K
R
Site 46
T399
P
G
C
D
K
R
F
T
E
Y
S
S
L
Y
K
Site 47
S402
D
K
R
F
T
E
Y
S
S
L
Y
K
H
H
V
Site 48
Y405
F
T
E
Y
S
S
L
Y
K
H
H
V
V
H
T
Site 49
S430
G
K
T
Y
K
Q
I
S
T
L
A
M
H
K
R
Site 50
S468
G
E
D
V
L
K
G
S
Q
I
T
Y
V
T
G
Site 51
Y472
L
K
G
S
Q
I
T
Y
V
T
G
V
E
G
D
Site 52
T490
S
T
Q
V
A
T
V
T
Q
S
G
L
S
Q
Q
Site 53
T499
S
G
L
S
Q
Q
V
T
L
I
S
Q
D
G
T
Site 54
S502
S
Q
Q
V
T
L
I
S
Q
D
G
T
Q
H
V
Site 55
T506
T
L
I
S
Q
D
G
T
Q
H
V
N
I
S
Q
Site 56
T531
T
M
V
T
Q
D
G
T
P
I
T
V
P
A
H
Site 57
T534
T
Q
D
G
T
P
I
T
V
P
A
H
D
A
V
Site 58
T575
Q
D
L
A
A
F
H
T
A
S
S
E
M
G
H
Site 59
T598
T
T
E
T
R
P
L
T
L
V
A
T
S
N
G
Site 60
S617
V
Q
L
G
E
Q
P
S
L
E
E
A
I
R
I
Site 61
S626
E
E
A
I
R
I
A
S
R
I
Q
Q
G
E
T
Site 62
T633
S
R
I
Q
Q
G
E
T
P
G
L
D
D
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation