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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
DGKQ
Full Name:
Diacylglycerol kinase theta
Alias:
DAG kinase theta; DAGK; DAGK4; DAGK7; DGK-theta; Diacylglycerol kinase, theta 110kDa; Diglyceride kinase theta
Type:
Lipid Metabolism - glycerolipid; EC 2.7.1.107; Lipid Metabolism - glycerophospholipid; Kinase, lipid
Mass (Da):
101136
Number AA:
942
UniProt ID:
P52824
International Prot ID:
IPI00005565
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005856
GO:0005829
GO:0016607
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0004143
GO:0019900
PhosphoSite+
KinaseNET
Biological Process:
GO:0007205
GO:0070528
GO:0034339
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S17
R
A
W
L
G
G
G
S
P
R
P
G
S
P
A
Site 2
S22
G
G
S
P
R
P
G
S
P
A
C
S
P
V
L
Site 3
S26
R
P
G
S
P
A
C
S
P
V
L
G
S
G
G
Site 4
S31
A
C
S
P
V
L
G
S
G
G
R
A
R
P
G
Site 5
S62
P
A
A
A
P
G
H
S
F
R
K
V
T
L
T
Site 6
T67
G
H
S
F
R
K
V
T
L
T
K
P
T
F
C
Site 7
T69
S
F
R
K
V
T
L
T
K
P
T
F
C
H
L
Site 8
T72
K
V
T
L
T
K
P
T
F
C
H
L
C
S
D
Site 9
S193
W
R
E
G
N
L
P
S
G
A
R
C
E
V
C
Site 10
T203
R
C
E
V
C
R
K
T
C
G
S
S
D
V
L
Site 11
S257
R
L
L
P
G
G
F
S
K
T
Q
S
F
R
I
Site 12
T259
L
P
G
G
F
S
K
T
Q
S
F
R
I
V
E
Site 13
S261
G
G
F
S
K
T
Q
S
F
R
I
V
E
A
A
Site 14
S280
G
G
D
G
A
D
G
S
A
A
V
G
P
G
R
Site 15
T289
A
V
G
P
G
R
E
T
Q
A
T
P
E
S
G
Site 16
T292
P
G
R
E
T
Q
A
T
P
E
S
G
K
Q
T
Site 17
S295
E
T
Q
A
T
P
E
S
G
K
Q
T
L
K
I
Site 18
T299
T
P
E
S
G
K
Q
T
L
K
I
F
D
G
D
Site 19
S312
G
D
D
A
V
R
R
S
Q
F
R
L
V
T
V
Site 20
S320
Q
F
R
L
V
T
V
S
R
L
A
G
A
E
E
Site 21
S353
E
L
C
R
L
P
P
S
S
Q
A
C
D
A
W
Site 22
S354
L
C
R
L
P
P
S
S
Q
A
C
D
A
W
A
Site 23
S367
W
A
G
G
K
A
G
S
A
V
I
S
E
E
G
Site 24
S371
K
A
G
S
A
V
I
S
E
E
G
R
S
P
G
Site 25
S376
V
I
S
E
E
G
R
S
P
G
S
G
E
A
T
Site 26
S379
E
E
G
R
S
P
G
S
G
E
A
T
P
E
A
Site 27
T383
S
P
G
S
G
E
A
T
P
E
A
W
V
I
R
Site 28
Y412
W
L
K
V
G
V
A
Y
V
S
V
R
V
T
P
Site 29
T418
A
Y
V
S
V
R
V
T
P
K
S
T
A
R
S
Site 30
S440
L
L
G
R
Q
A
E
S
P
E
S
F
Q
L
V
Site 31
S443
R
Q
A
E
S
P
E
S
F
Q
L
V
E
V
A
Site 32
S478
L
Q
D
I
R
Q
M
S
V
R
Q
V
S
Q
T
Site 33
S483
Q
M
S
V
R
Q
V
S
Q
T
R
F
Y
V
A
Site 34
T485
S
V
R
Q
V
S
Q
T
R
F
Y
V
A
E
S
Site 35
Y488
Q
V
S
Q
T
R
F
Y
V
A
E
S
R
D
V
Site 36
S511
G
G
L
P
P
G
L
S
P
E
E
Y
S
S
L
Site 37
Y515
P
G
L
S
P
E
E
Y
S
S
L
L
H
E
A
Site 38
S517
L
S
P
E
E
Y
S
S
L
L
H
E
A
G
A
Site 39
S533
K
A
T
V
V
S
V
S
H
I
Y
S
S
Q
G
Site 40
S597
L
V
F
V
N
P
K
S
G
G
L
K
G
R
D
Site 41
S608
K
G
R
D
L
L
C
S
F
R
K
L
L
N
P
Site 42
T622
P
H
Q
V
F
D
L
T
N
G
G
P
L
P
G
Site 43
Y662
G
A
L
E
E
T
R
Y
R
L
A
C
P
E
P
Site 44
Y692
V
L
R
W
G
A
G
Y
S
G
E
D
P
F
S
Site 45
S693
L
R
W
G
A
G
Y
S
G
E
D
P
F
S
V
Site 46
S699
Y
S
G
E
D
P
F
S
V
L
L
S
V
D
E
Site 47
T731
A
G
S
A
E
N
D
T
A
D
A
E
P
P
K
Site 48
S755
I
G
I
D
A
E
L
S
L
D
F
H
Q
A
R
Site 49
Y779
R
L
H
N
K
G
V
Y
V
R
V
G
L
Q
K
Site 50
S788
R
V
G
L
Q
K
I
S
H
S
R
S
L
H
K
Site 51
S792
Q
K
I
S
H
S
R
S
L
H
K
Q
I
R
L
Site 52
S831
S
G
A
D
L
W
G
S
D
S
D
T
R
F
E
Site 53
S833
A
D
L
W
G
S
D
S
D
T
R
F
E
K
P
Site 54
T835
L
W
G
S
D
S
D
T
R
F
E
K
P
R
M
Site 55
S867
Q
V
Q
G
G
L
R
S
G
I
R
I
A
Q
G
Site 56
T885
R
V
T
L
L
K
A
T
P
V
Q
V
D
G
E
Site 57
T925
Q
K
P
R
R
A
G
T
T
R
D
A
R
A
D
Site 58
S939
D
A
A
P
A
P
E
S
D
P
R
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation