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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PDX1
Full Name:
Pancreas/duodenum homeobox protein 1
Alias:
Glucose-sensitive factor;Insulin promoter factor 1;Insulin upstream factor 1;Islet/duodenum homeobox-1;Somatostatin-transactivating factor 1
Type:
Transcription protein
Mass (Da):
30771
Number AA:
283
UniProt ID:
P52945
International Prot ID:
IPI00006036
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0043565
GO:0003704
GO:0003700
PhosphoSite+
KinaseNET
Biological Process:
GO:0006091
GO:0030073
GO:0007263
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y8
M
N
G
E
E
Q
Y
Y
A
A
T
Q
L
Y
K
Site 2
T11
E
E
Q
Y
Y
A
A
T
Q
L
Y
K
D
P
C
Site 3
Y14
Y
Y
A
A
T
Q
L
Y
K
D
P
C
A
F
Q
Site 4
S29
R
G
P
A
P
E
F
S
A
S
P
P
A
C
L
Site 5
Y37
A
S
P
P
A
C
L
Y
M
G
R
Q
P
P
P
Site 6
S61
L
G
A
L
E
Q
G
S
P
P
D
I
S
P
Y
Site 7
S66
Q
G
S
P
P
D
I
S
P
Y
E
V
P
P
L
Site 8
Y68
S
P
P
D
I
S
P
Y
E
V
P
P
L
A
D
Site 9
S124
L
P
F
P
W
M
K
S
T
K
A
H
A
W
K
Site 10
T125
P
F
P
W
M
K
S
T
K
A
H
A
W
K
G
Site 11
T149
E
P
E
E
N
K
R
T
R
T
A
Y
T
R
A
Site 12
T151
E
E
N
K
R
T
R
T
A
Y
T
R
A
Q
L
Site 13
Y153
N
K
R
T
R
T
A
Y
T
R
A
Q
L
L
E
Site 14
Y170
K
E
F
L
F
N
K
Y
I
S
R
P
R
R
V
Site 15
S172
F
L
F
N
K
Y
I
S
R
P
R
R
V
E
L
Site 16
T213
D
K
K
R
G
G
G
T
A
V
G
G
G
G
V
Site 17
T230
P
E
Q
D
C
A
V
T
S
G
E
E
L
L
A
Site 18
S231
E
Q
D
C
A
V
T
S
G
E
E
L
L
A
L
Site 19
S266
G
R
L
P
P
G
L
S
A
S
P
Q
P
S
S
Site 20
S268
L
P
P
G
L
S
A
S
P
Q
P
S
S
V
A
Site 21
S272
L
S
A
S
P
Q
P
S
S
V
A
P
R
R
P
Site 22
S273
S
A
S
P
Q
P
S
S
V
A
P
R
R
P
Q
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation